Detail

Contains

UniProtKB-A8MVW0


Protein	Protein FAM171A2
Gene	FAM171A2
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); HEK293 cell line (embryonic kidney); Liver; Lymphocytes; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Pancreatic islets; Prostate tumor
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
66	ASVDVFGnR	2014(15); 2014(16); 2014(18); 2014(33); 2015(1); 2015(unpublished);2007(unpublished);2007;
66	SVDVFGnRTIIAA	2013(37);
221	LLTGnGTEVPLSGPIHLSLPVPSETR	2007(unpublished);2007(unpublished);
265	nGTGVIR	2015(unpublished);
265	FDPKSGLWVRnGTGVIR	2012(48);

Sequence

1	11	21	31	41	51	61	71	81	91
MPPASGPSVL	ARLLPLLGLL	LGSASRAPGK	SPPEPPSPQE	ILIKVQVYVS	GELVPLARAS	VDVFGNRTLL	AAGTTDSEGV	ATLPLSYRLG	TWVLVTAARP
101	111	121	131	141	151	161	171	181	191
GFLTNSVPWR	VDKLPLYASV	SLYLLPERPA	TLILYEDLVH	ILLGSPGARS	QPLVQFQRRA	ARLPVSSTYS	QLWASLTPAS	TQQEMRAFPA	FLGTEASSSG
201	211	221	231	241	251	261	271	281	291
NGSWLELMPL	TAVSVHLLTG	NGTEVPLSGP	IHLSLPVPSE	TRALTVGTSI	PAWRFDPKSG	LWVRNGTGVI	RKEGRQLYWT	FVSPQLGYWV	AAMASPTAGL
301	311	321	331	341	351	361	371	381	391
VTITSGIQDI	GTYHTIFLLT	ILAALALLVL	ILLCLLIYYC	RRRCLKPRQQ	HRKLQLSGPS	DGNKRDQATS	MSQLHLICGG	PLEPAPSGDP	EAPPPGPLHS
401	411	421	431	441	451	461	471	481	491
AFSSSRDLAS	SRDDFFRTKP	RSASRPAAEP	SGARGGESAG	LKGARSAEGP	GGLEPGLEEH	RRGPSGAAAF	LHEPPSPPPP	FDHYLGHKGA	AEGKTPDFLL
501	511	521	531	541	551	561	571	581	591
SQSVDQLARP	PSLGQAGQLI	FCGSIDHLKD	NVYRNVMPTL	VIPAHYVRLG	GEAGAAGVGD	EPAPPEGTAP	GPARAFPQPD	PQRPQMPGHS	GPGGEGGGGG
601	611	621	631	641	651	661	671	681	691
GEGWGAGRAA	PVSGSVTIPV	LFNESTMAQL	NGELQALTEK	KLLELGVKPH	PRAWFVSLDG	RSNSQVRHSY	IDLQAGGGAR	STDASLDSGV	DVHEARPARR
701	711	721	731	741	751	761	771	781	791
RPAREERERA	PPAAPPPPPA	PPRLALSEDT	EPSSSESRTG	LCSPEDNSLT	PLLDEVAAPE	GRAATVPRGR	GRSRGDSSRS	SASELRRDSL	TSPEDELGAE
801	811	821
VGDEAGDKKS	PWQRREERPL	MVFNVK

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
15	Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.