Contains      

UniProtKB-O14498

Protein Immunoglobulin superfamily containing leucine-rich repeat protein
Gene ISLR
Status Reviewed
Source Breast cancer xenografts; Breast tumor; Cerebrospinal fluid; Liver; Ovarian tumor; Platelet; Prostate tumor; Serum; Urine
Years 2007-2015

Glycosites

Site Identified Peptides Year(Publication ID)
51 DLESVPPGFPAnVTTLSLSANR 2007(unpublished);2015(unpublished);2015(unpublished);2015;2015;2015;2015;2007;2007;2007;
51 DLESVPPGFPAnVTTLSLSANRLPGLPEGAFR 2015(unpublished);
120 SLDLSHNLISDFAWSDLHnLSALQLLK 2014(33); 2015(10); 2015(unpublished);2015(unpublished);2007(unpublished);2007(unpublished);2007;2007;
309 AnGSLLIPDFGK 2015(unpublished);
309 FQAFAnGSLLIPD 2014(33);
309 FQAFAnGSLLIPDFGK 2007(45); 2013(33); 2014(10); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015;2015;2007;2007;2007;2007;2007;

Sequence

1112131415161718191
MQELHLLWWALLLGLAQACPEPCDCGEKYGFQIADCAYRDLESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHL
101111121131141151161171181191
KSLDLSHNLISDFAWSDLHNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWALTTAV
201211221231241251261271281291
SIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQLSYQPSQDGAELRPGFVLALHCDVDGQPAPQLHWHIQIPSGIVEITSPNVGTDGRALPGTPVASS
301311321331341351361371381391
QPRFQAFANGSLLIPDFGKLEEGTYSCLATNELGSAESSVDVALATPGEGGEDTLGRRFHGKAVEGKGCYTVDNEVQPSGPEDNVVIIYLSRAGNPEAAV
401411421
AEGVPGQLPPGLLLLGQSLLLFFFLTSF

Reference

ID Publication
10Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
45Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.