Detail


Protein	PDZ domain-containing protein 2
Gene	PDZD2
Status	Reviewed
Source	Colorectal tumors; OVCAR-3 cell line (Ovarian cancer); Pancreatic islets; Prostate tumor; Urine
Years	2007-2015

Site	Identified Peptides	Year(Publication ID)
839	EAnSSPGLGTPLK	2007(unpublished);2007(unpublished);2007;
1058	nLTDSAEAPK	2015(1);
1144	RSEAEAKPSGSQTVnLTGR	2009(68);
1522	LSnYSR	2012(48);
2403	SLSSCSEnQSEAGTLLPQMAK	2009(68);

Sequence

1	11	21	31	41	51	61	71	81	91
MPITQDNAVL	HLPLLYQWLQ	NSLQEGGDGP	EQRLCQAAIQ	KLQEYIQLNF	AVDESTVPPD	HSPPEMEICT	VYLTKELGDT	ETVGLSFGNI	PVFGDYGEKR
101	111	121	131	141	151	161	171	181	191
RGGKKRKTHQ	GPVLDVGCIW	VTELRKNSPA	GKSGKVRLRD	EILSLNGQLM	VGVDVSGASY	LAEQCWNGGF	IYLIMLRRFK	HKAHSTYNGN	SSNSSEPGET
201	211	221	231	241	251	261	271	281	291
PTLELGDRTA	KKGKRTRKFG	VISRPPANKA	PEESKGSAGC	EVSSDPSTEL	ENGPDPELGN	GHVFQLENGP	DSLKEVAGPH	LERSEVDRGT	EHRIPKTDAP
301	311	321	331	341	351	361	371	381	391
LTTSNDKRRF	SKGGKTDFQS	SDCLAREEVG	RIWKMELLKE	SDGLGIQVSG	GRGSKRSPHA	IVVTQVKEGG	AAHRDGRLSL	GDELLVINGH	LLVGLSHEEA
401	411	421	431	441	451	461	471	481	491
VAILRSATGM	VQLVVASKEN	SAEDLLRLTS	KSLPDLTSSV	EDVSSWTDNE	DQEADGEEDE	GTSSSVQRAM	PGTDEPQDVC	GAEESKGNLE	SPKQGSNKIK
501	511	521	531	541	551	561	571	581	591
LKSRLSGGVH	RLESVEEYNE	LMVRNGDPRI	RMLEVSRDGR	KHSLPQLLDS	SSASQEYHIV	KKSTRSLSTT	QVESPWRLIR	PSVISIIGLY	KEKGKGLGFS
601	611	621	631	641	651	661	671	681	691
IAGGRDCIRG	QMGIFVKTIF	PNGSAAEDGR	LKEGDEILDV	NGIPIKGLTF	QEAIHTFKQI	RSGLFVLTVR	TKLVSPSLTP	CSTPTHMSRS	ASPNFNTSGG
701	711	721	731	741	751	761	771	781	791
ASAGGSDEGS	SSSLGRKTPG	PKDRIVMEVT	LNKEPRVGLG	IGACCLALEN	SPPGIYIHSL	APGSVAKMES	NLSRGDQILE	VNSVNVRHAA	LSKVHAILSK
801	811	821	831	841	851	861	871	881	891
CPPGPVRLVI	GRHPNPKVSE	QEMDEVIARS	TYQESKEANS	SPGLGTPLKS	PSLAKKDSLI	SESELSQYFA	HDVPGPLSDF	MVAGSEDEDH	PGSGCSTSEE
901	911	921	931	941	951	961	971	981	991
GSLPPSTSTH	KEPGKPRANS	LVTLGSHRAS	GLFHKQVTVA	RQASLPGSPQ	ALRNPLLRQR	KVGCYDANDA	SDEEEFDREG	DCISLPGALP	GPIRPLSEDD
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
PRRVSISSSK	GMDVHNQEER	PRKTLVSKAI	SAPLLGSSVD	LEESIPEGMV	DAASYAANLT	DSAEAPKGSP	GSWWKKELSG	SSSAPKLEYT	VRTDTQSPTN
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
TGSPSSPQQK	SEGLGSRHRP	VARVSPHCKR	SEAEAKPSGS	QTVNLTGRAN	DPCDLDSRVQ	ATSVKVTVAG	FQPGGAVEKE	SLGKLTTGDA	CVSTSCELAS
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
ALSHLDASHL	TENLPKAASE	LGQQPMTELD	SSSDLISSPG	KKGAAHPDPS	KTSVDTGQVS	RPENPSQPAS	PRVTKCKARS	PVRLPHEGSP	SPGEKAAAPP
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
DYSKTRSASE	TSTPHNTRRV	AALRGAGPGA	EGMTPAGAVL	PGDPLTSQEQ	RQGAPGNHSK	ALEMTGIHAP	ESSQEPSLLE	GADSVSSRAP	QASLSMLPST
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
DNTKEACGHV	SGHCCPGGSR	ESPVTDIDSF	IKELDASAAR	SPSSQTGDSG	SQEGSAQGHP	PAGAGGGSSC	RAEPVPGGQT	SSPRRAWAAG	APAYPQWASQ
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
PSVLDSINPD	KHFTVNKNFL	SNYSRNFSSF	HEDSTSLSGL	GDSTEPSLSS	MYGDAEDSSS	DPESLTEAPR	ASARDGWSPP	RSRVSLHKED	PSESEEEQIE
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
ICSTRGCPNP	PSSPAHLPTQ	AAICPASAKV	LSLKYSTPRE	SVASPREKAA	CLPGSYTSGP	DSSQPSSLLE	MSSQEHETHA	DISTSQNHRP	SCAEETTEVT
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
SASSAMENSP	LSKVARHFHS	PPIILSSPNM	VNGLEHDLLD	DETLNQYETS	INAAASLSSF	SVDVPKNGES	VLENLHISES	QDLDDLLQKP	KMIARRPIMA
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
WFKEINKHNQ	GTHLRSKTEK	EQPLMPARSP	DSKIQMVSSS	QKKGVTVPHS	PPQPKTNLEN	KDLSKKSPAE	MLLTNGQKAK	CGPKLKRLSL	KGKAKVNSEA
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
PAANAVKAGG	TDHRKPLISP	QTSHKTLSKA	VSQRLHVADH	EDPDRNTTAA	PRSPQCVLES	KPPLATSGPL	KPSVSDTSIR	TFVSPLTSPK	PVPEQGMWSR
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
FHMAVLSEPD	RGCPTTPKSP	KCRAEGRAPR	ADSGPVSPAA	SRNGMSVAGN	RQSEPRLASH	VAADTAQPRP	TGEKGGNIMA	SDRLERTNQL	KIVEISAEAV
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
SETVCGNKPA	ESDRRGGCLA	QGNCQEKSEI	RLYRQVAESS	TSHPSSLPSH	ASQAEQEMSR	SFSMAKLASS	SSSLQTAIRK	AEYSQGKSSL	MSDSRGVPRN
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
SIPGGPSGED	HLYFTPRPAT	RTYSMPAQFS	SHFGREGHPP	HSLGRSRDSQ	VPVTSSVVPE	AKASRGGLPS	LANGQGIYSV	KPLLDTSRNL	PATDEGDIIS
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
VQETSCLVTD	KIKVTRRHYC	YEQNWPHEST	SFFSVKQRIK	SFENLANADR	PVAKSGASPF	LSVSSKPPIG	RRSSGSIVSG	SLGHPGDAAA	RLLRRSLSSC
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
SENQSEAGTL	LPQMAKSPSI	MTLTISRQNP	PETSSKGSDS	ELKKSLGPLG	IPTPTMTLAS	PVKRNKSSVR	HTQPSPVSRS	KLQELRALSM	PDLDKLCSED
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
YSAGPSAVLF	KTELEITPRR	SPGPPAGGVS	CPEKGGNRAC	PGGSGPKTSA	AETPSSASDT	GEAAQDLPFR	RSWSVNLDQL	LVSAGDQQRL	QSVLSSVGSK
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
STILTLIQEA	KAQSENEEDV	CFIVLNRKEG	SGLGFSVAGG	TDVEPKSITV	HRVFSQGAAS	QEGTMNRGDF	LLSVNGASLA	GLAHGNVLKV	LHQAQLHKDA
2701	2711	2721	2731	2741	2751	2761	2771	2781	2791
LVVIKKGMDQ	PRPSARQEPP	TANGKGLLSR	KTIPLEPGIG	RSVAVHDALC	VEVLKTSAGL	GLSLDGGKSS	VTGDGPLVIK	RVYKGGAAEQ	AGIIEAGDEI
2801	2811	2821	2831
LAINGKPLVG	LMHFDAWNIM	KSVPEGPVQL	LIRKHRNSS

UniProtKB-O15018

Glycosites

Sequence

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
68	Zhang L, Xu Y, Yao H, Xie L, Yao J, Lu H, Yang P: Boronic Acid Functionalized Core-Satellite Composite Nanoparticles for Advanced Enrichment of Glycopeptides and Glycoproteins. Chemistry-a European Journal 2009, 15:10158-10166.