Detail


Protein	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Gene	INPPL1
Status	Reviewed
Source	LNCap/PC3 cell lines (Prostate cancer); OVCAR-3 cell line (Ovarian cancer)
Years	2015-2015

Site	Identified Peptides	Year(Publication ID)
551	nGTSFGFVNCHLTSGNEK	2015(1);
551	TGIANTLGNKGAVGVSFMFnGTSFGFVNCHLTSGNEKTAR	2015(2);

Sequence

1	11	21	31	41	51	61	71	81	91
MASACGAPGP	GGALGSQAPS	WYHRDLSRAA	AEELLARAGR	DGSFLVRDSE	SVAGAFALCV	LYQKHVHTYR	ILPDGEDFLA	VQTSQGVPVR	RFQTLGELIG
101	111	121	131	141	151	161	171	181	191
LYAQPNQGLV	CALLLPVEGE	REPDPPDDRD	ASDGEDEKPP	LPPRSGSTSI	SAPTGPSSPL	PAPETPTAPA	AESAPNGLST	VSHDYLKGSY	GLDLEAVRGG
201	211	221	231	241	251	261	271	281	291
ASHLPHLTRT	LATSCRRLHS	EVDKVLSGLE	ILSKVFDQQS	SPMVTRLLQQ	QNLPQTGEQE	LESLVLKLSV	LKDFLSGIQK	KALKALQDMS	STAPPAPQPS
301	311	321	331	341	351	361	371	381	391
TRKAKTIPVQ	AFEVKLDVTL	GDLTKIGKSQ	KFTLSVDVEG	GRLVLLRRQR	DSQEDWTTFT	HDRIRQLIKS	QRVQNKLGVV	FEKEKDRTQR	KDFIFVSARK
401	411	421	431	441	451	461	471	481	491
REAFCQLLQL	MKNKHSKQDE	PDMISVFIGT	WNMGSVPPPK	NVTSWFTSKG	LGKTLDEVTV	TIPHDIYVFG	TQENSVGDRE	WLDLLRGGLK	ELTDLDYRPI
501	511	521	531	541	551	561	571	581	591
AMQSLWNIKV	AVLVKPEHEN	RISHVSTSSV	KTGIANTLGN	KGAVGVSFMF	NGTSFGFVNC	HLTSGNEKTA	RRNQNYLDIL	RLLSLGDRQL	NAFDISLRFT
601	611	621	631	641	651	661	671	681	691
HLFWFGDLNY	RLDMDIQEIL	NYISRKEFEP	LLRVDQLNLE	REKHKVFLRF	SEEEISFPPT	YRYERGSRDT	YAWHKQKPTG	VRTNVPSWCD	RILWKSYPET
701	711	721	731	741	751	761	771	781	791
HIICNSYGCT	DDIVTSDHSP	VFGTFEVGVT	SQFISKKGLS	KTSDQAYIEF	ESIEAIVKTA	SRTKFFIEFY	STCLEEYKKS	FENDAQSSDN	INFLKVQWSS
801	811	821	831	841	851	861	871	881	891
RQLPTLKPIL	ADIEYLQDQH	LLLTVKSMDG	YESYGECVVA	LKSMIGSTAQ	QFLTFLSHRG	EETGNIRGSM	KVRVPTERLG	TRERLYEWIS	IDKDEAGAKS
901	911	921	931	941	951	961	971	981	991
KAPSVSRGSQ	EPRSGSRKPA	FTEASCPLSR	LFEEPEKPPP	TGRPPAPPRA	APREEPLTPR	LKPEGAPEPE	GVAAPPPKNS	FNNPAYYVLE	GVPHQLLPPE
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
PPSPARAPVP	SATKNKVAIT	VPAPQLGHHR	HPRVGEGSSS	DEESGGTLPP	PDFPPPPLPD	SAIFLPPSLD	PLPGPVVRGR	GGAEARGPPP	PKAHPRPPLP
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
PGPSPASTFL	GEVASGDDRS	CSVLQMAKTL	SEVDYAPAGP	ARSALLPGPL	ELQPPRGLPS	DYGRPLSFPP	PRIRESIQED	LAEEAPCLQG	GRASGLGEAG
1201	1211	1221	1231	1241	1251
MSAWLRAIGL	ERYEEGLVHN	GWDDLEFLSD	ITEEDLEEAG	VQDPAHKRLL	LDTLQLSK

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.

UniProtKB-O15357

Glycosites

Sequence

Reference