Detail

Contains

UniProtKB-O43318


Protein	Mitogen-activated protein kinase kinase kinase 7
Gene	MAP3K7
Status	Reviewed
Source	OVCAR-3 cell line (Ovarian cancer); Prostate; Prostate tumor; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
245	nGTRPPLIK	2015(1);
326	MDIASTnTSNK	2014(14);
329	MDIASTNTSnK	2014(14);
342	SDTNMEQVPATnDTIKR	2007(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MSTASAASSS	SSSSAGEMIE	APSQVLNFEE	IDYKEIEVEE	VVGRGAFGVV	CKAKWRAKDV	AIKQIESESE	RKAFIVELRQ	LSRVNHPNIV	KLYGACLNPV
101	111	121	131	141	151	161	171	181	191
CLVMEYAEGG	SLYNVLHGAE	PLPYYTAAHA	MSWCLQCSQG	VAYLHSMQPK	ALIHRDLKPP	NLLLVAGGTV	LKICDFGTAC	DIQTHMTNNK	GSAAWMAPEV
201	211	221	231	241	251	261	271	281	291
FEGSNYSEKC	DVFSWGIILW	EVITRRKPFD	EIGGPAFRIM	WAVHNGTRPP	LIKNLPKPIE	SLMTRCWSKD	PSQRPSMEEI	VKIMTHLMRY	FPGADEPLQY
301	311	321	331	341	351	361	371	381	391
PCQYSDEGQS	NSATSTGSFM	DIASTNTSNK	SDTNMEQVPA	TNDTIKRLES	KLLKNQAKQQ	SESGRLSLGA	SRGSSVESLP	PTSEGKRMSA	DMSEIEARIA
401	411	421	431	441	451	461	471	481	491
ATTAYSKPKR	GHRKTASFGN	ILDVPEIVIS	GNGQPRRRSI	QDLTVTGTEP	GQVSSRSSSP	SVRMITTSGP	TSEKPTRSHP	WTPDDSTDTN	GSDNSIPMAY
501	511	521	531	541	551	561	571	581	591
LTLDHQLQPL	APCPNSKESM	AVFEQHCKMA	QEYMKVQTEI	ALLLQRKQEL	VAELDQDEKD	QQNTSRLVQE	HKKLLDENKS	LSTYYQQCKK	QLEVIRSQQQ
601
KRQGTS

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.