Contains      

UniProtKB-O43451

Protein Maltase-glucoamylase, intestinal
Gene MGAM
Status Reviewed
Source Breast Cancer cell lines; Breast cancer xenografts; Human; Liver; Prostate; Prostate tumor; Spermatozoa; Urine
Years 2007-2015

Glycosites

Site Identified Peptides Year(Publication ID)
135 nHSYHVEGNLVNTNAGFTAR 2015(unpublished);2015(unpublished);
295 IFNRDTTPNGnGTNLYGAQT 2015(6);
457 LVIIVDPAISnNSSSSKPYGPYDR 2007(unpublished);2015(unpublished);2015;2015;2007;2007;
458 LVIIVDPAISNnSSSSKPYGPYDR 2007(unpublished);2015(unpublished);2015;2015;2007;2007;
707 DQDPASFGADSLLLnSSR 2015(unpublished);2015(unpublished);2015(unpublished);
707 NHNGQGYKDQDPASFGADSLLLnSSR 2007(unpublished);2015(unpublished);2015;2015;2007;2007;
827 GGYIFPTQQPnTTTLASR 2007(unpublished);2015(unpublished);2015;2007;2007;
827 GGYIFPTQQPnTTTLASRKN 2015(6);
885 LEVnISQSTYK 2007(14); 2014(unpublished);2015(unpublished);2015;2015;2007;2007;
885 LEVnISQSTYKDPNNLAFNEIK 2015(unpublished);2015(unpublished);2015(unpublished);
912 ILGTEEPSnVTVK 2007(14); 2014(unpublished);2015(unpublished);2015;2007;2007;
977 IDCYPDENGASAEnCTAR 2007(45); 2013(unpublished);2015(unpublished);2015;2007;2007;
977 IRDEEKIDCYPDENGASAEnCTAR 2015(unpublished);2015(unpublished);
1323 DPAISGnETQPYP 2013(37);
1323 VIIIIDPAISGnETQPYPAFTR 2014(32);
1323 VILILDPAISGnETQPYPAFTR 2007(45); 2013(33); 2014(unpublished);2015(unpublished);2015;2015;2007;2007;
1388 AYVAFPDFFRnSTAK 2007(unpublished);2007(unpublished);2007;
1603 QDPVSWDVAFVnISR 2007(33); 2014(unpublished);2015(unpublished);2015;2015;2007;2007;
1603 RQDPVSWDVAFVnISR 2013(43); 2015(unpublished);2015(unpublished);2015(unpublished);
1672 nVTAYFPR 2007(45); 2013(33); 2014(unpublished);2015(unpublished);2015;2007;2007;
1842 nISLHNFTSL 2007(unpublished);2007(unpublished);2007;
1847 NISLHnFTSL 2007(unpublished);2007(unpublished);2007;

Sequence

1112131415161718191
MARKKLKKFTTLEIVLSVLLLVLFIISIVLIVLLAKESLKSTAPDPGTTGTPDPGTTGTPDPGTTGTTHARTTGPPDPGTTGTTPVSAECPVVNELERIN
101111121131141151161171181191
CIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHE
201211221231241251261271281291
HVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLY
301311321331341351361371381391
GAQTFFLCLEDASGLSFGVFLMNSNAMEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERN
401411421431441451461471481491
RAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPD
501511521531541551561571581591
YTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKT
601611621631641651661671681691
VFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFG
701711721731741751761771781791
ADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQ
801811821831841851861871881891
KVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFN
901911921931941951961971981991
EIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIRDEEKIDCYPDENGASAENCTARGCIWEASNSSGVPFCYFVN
1001101110211031104110511061107110811091
DLYSVSDVQYNSHGATADISLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTPEGQLYDVLIKKNPFGIEIRRKS
1101111111211131114111511161117111811191
TGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGFGETEHRSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPL
1201121112211231124112511261127112811291
PALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPA
1301131113211331134113511361137113811391
LINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYVAFPDFFRNSTAKWWKREIEE
1401141114211431144114511461147114811491
LYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQEV
1501151115211531154115511561157115811591
TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVA
1601161116211631164116511661167116811691
FVNISRTVLQTRYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRARWYDYYTGVDINARGEWKTL
1701171117211731174117511761177117811791
PAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIE
180118111821183118411851
IWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL

Reference

ID Publication
6Kim DS, Hahn Y: The acquisition of novel N-glycosylation sites in conserved proteins during human evolution. Bmc Bioinformatics 2015, 16.
14Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
32Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
37Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
43Wang GG, Wu YB, Zhou T, Guo YS, Zheng B, Wang J, Bi Y, Liu FJ, Zhou ZM, Guo XJ, Sha JH: Mapping of the N-Linked Glycoproteome of Human Spermatozoa. Journal of Proteome Research 2013, 12:5750-5759.
45Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.