Detail

UniProtKB-O75339


Protein	Cartilage intermediate layer protein 1
Gene	CILP
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer xenografts; Breast tumor; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
129	nCSNYTVR	2015(1);
129	EQRPGQnCSNYTV	2013(37);
129	EQRPGQnCSNYTVR	2013(34); 2014(16); 2014(22); 2015(unpublished);2015(unpublished);2015;2015;2015;2007;2007;
132	NCSnYTVR	2015(1);
132	EQRPGQNCSnYTV	2013(37);
132	EQRPGQNCSnYTVR	2013(34); 2014(16); 2014(22); 2015(unpublished);2015(unpublished);2015;2015;2015;2007;2007;
346	nDTLLDPSLYK	2015(1);
346	YFWYHnDTLLDPSLYK	2015(unpublished);2015(1);
420	nATNSFYYDVGR	2015(1);
420	IPHDCFQnATNSFYYDVGR	2014(16);
420	LPHDCFQnATNSFYYDVGR	2007(34); 2013(33); 2014(unpublished);2015(unpublished);2015;2015;2007;2007;
550	FVnTTK	2015(unpublished);
631	nISTATAAQTDLNFINDEGDTFPLR	2015(unpublished);
1056	ASVNPMLHEYLVNHLPLAVNnDTSEYTM	2007(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MVGTKAWVFS	FLVLEVTSVL	GRQTMLTQSV	RRVQPGKKNP	SIFAKPADTL	ESPGEWTTWF	NIDYPGGKGD	YERLDAIRFY	YGDRVCARPL	RLEARTTDWT
101	111	121	131	141	151	161	171	181	191
PAGSTGQVVH	GSPREGFWCL	NREQRPGQNC	SNYTVRFLCP	PGSLRRDTER	IWSPWSPWSK	CSAACGQTGV	QTRTRICLAE	MVSLCSEASE	EGQHCMGQDC
201	211	221	231	241	251	261	271	281	291
TACDLTCPMG	QVNADCDACM	CQDFMLHGAV	SLPGGAPASG	AAIYLLTKTP	KLLTQTDSDG	RFRIPGLCPD	GKSILKITKV	KFAPIVLTMP	KTSLKAATIK
301	311	321	331	341	351	361	371	381	391
AEFVRAETPY	MVMNPETKAR	RAGQSVSLCC	KATGKPRPDK	YFWYHNDTLL	DPSLYKHESK	LVLRKLQQHQ	AGEYFCKAQS	DAGAVKSKVA	QLIVIASDET
401	411	421	431	441	451	461	471	481	491
PCNPVPESYL	IRLPHDCFQN	ATNSFYYDVG	RCPVKTCAGQ	QDNGIRCRDA	VQNCCGISKT	EEREIQCSGY	TLPTKVAKEC	SCQRCTETRS	IVRGRVSAAD
501	511	521	531	541	551	561	571	581	591
NGEPMRFGHV	YMGNSRVSMT	GYKGTFTLHV	PQDTERLVLT	FVDRLQKFVN	TTKVLPFNKK	GSAVFHEIKM	LRRKKPITLE	AMETNIIPLG	EVVGEDPMAE
601	611	621	631	641	651	661	671	681	691
LEIPSRSFYR	QNGEPYIGKV	KASVTFLDPR	NISTATAAQT	DLNFINDEGD	TFPLRTYGMF	SVDFRDEVTS	EPLNAGKVKV	HLDSTQVKMP	EHISTVKLWS
701	711	721	731	741	751	761	771	781	791
LNPDTGLWEE	EGDFKFENQR	RNKREDRTFL	VGNLEIRERR	LFNLDVPESR	RCFVKVRAYR	SERFLPSEQI	QGVVISVINL	EPRTGFLSNP	RAWGRFDSVI
801	811	821	831	841	851	861	871	881	891
TGPNGACVPA	FCDDQSPDAY	SAYVLASLAG	EELQAVESSP	KFNPNAIGVP	QPYLNKLNYR	RTDHEDPRVK	KTAFQISMAK	PRPNSAEESN	GPIYAFENLR
901	911	921	931	941	951	961	971	981	991
ACEEAPPSAA	HFRFYQIEGD	RYDYNTVPFN	EDDPMSWTED	YLAWWPKPME	FRACYIKVKI	VGPLEVNVRS	RNMGGTHRQT	VGKLYGIRDV	RSTRDRDQPN
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
VSAACLEFKC	SGMLYDQDRV	DRTLVKVIPQ	GSCRRASVNP	MLHEYLVNHL	PLAVNNDTSE	YTMLAPLDPL	GHNYGIYTVT	DQDPRTAKEI	ALGRCFDGTS
1101	1111	1121	1131	1141	1151	1161	1171	1181
DGSSRIMKSN	VGVALTFNCV	ERQVGRQSAF	QYLQSTPAQS	PAAGTVQGRV	PSRRQQRASR	GGQRQGGVVA	SLRFPRVAQQ	PLIN

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.