Detail


Protein	Filamin-B
Gene	FLNB
Status	Reviewed
Source	Breast cancer xenografts; Colorectal tumors; Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Serum; Urine
Years	2007-2015

Site	Identified Peptides	Year(Publication ID)
79	QMQLEnVSVALEFLDR	2007(unpublished);2007(unpublished);2007;
1001	VVPCLVTPVTGREnSTAK	2009(68);
2125	nSSDMSAHVTSPSGR	2015(1);
2125	IPEInSSDMSAHVTSPSGR	2015(unpublished);
2362	FnGSHVVGSPFK	2014(33);
2483	nETSSILVESVTR	2015(1);
2570	HVGNQQYnVTYVVKER	2007(unpublished);2007(unpublished);2007(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MPVTEKDLAE	DAPWKKIQQN	TFTRWCNEHL	KCVNKRIGNL	QTDLSDGLRL	IALLEVLSQK	RMYRKYHQRP	TFRQMQLENV	SVALEFLDRE	SIKLVSIDSK
101	111	121	131	141	151	161	171	181	191
AIVDGNLKLI	LGLVWTLILH	YSISMPVWED	EGDDDAKKQT	PKQRLLGWIQ	NKIPYLPITN	FNQNWQDGKA	LGALVDSCAP	GLCPDWESWD	PQKPVDNARE
201	211	221	231	241	251	261	271	281	291
AMQQADDWLG	VPQVITPEEI	IHPDVDEHSV	MTYLSQFPKA	KLKPGAPLKP	KLNPKKARAY	GRGIEPTGNM	VKQPAKFTVD	TISAGQGDVM	VFVEDPEGNK
301	311	321	331	341	351	361	371	381	391
EEAQVTPDSD	KNKTYSVEYL	PKVTGLHKVT	VLFAGQHISK	SPFEVSVDKA	QGDASKVTAK	GPGLEAVGNI	ANKPTYFDIY	TAGAGVGDIG	VEVEDPQGKN
401	411	421	431	441	451	461	471	481	491
TVELLVEDKG	NQVYRCVYKP	MQPGPHVVKI	FFAGDTIPKS	PFVVQVGEAC	NPNACRASGR	GLQPKGVRIR	ETTDFKVDTK	AAGSGELGVT	MKGPKGLEEL
501	511	521	531	541	551	561	571	581	591
VKQKDFLDGV	YAFEYYPSTP	GRYSIAITWG	GHHIPKSPFE	VQVGPEAGMQ	KVRAWGPGLH	GGIVGRSADF	VVESIGSEVG	SLGFAIEGPS	QAKIEYNDQN
601	611	621	631	641	651	661	671	681	691
DGSCDVKYWP	KEPGEYAVHI	MCDDEDIKDS	PYMAFIHPAT	GGYNPDLVRA	YGPGLEKSGC	IVNNLAEFTV	DPKDAGKAPL	KIFAQDGEGQ	RIDIQMKNRM
701	711	721	731	741	751	761	771	781	791
DGTYACSYTP	VKAIKHTIAV	VWGGVNIPHS	PYRVNIGQGS	HPQKVKVFGP	GVERSGLKAN	EPTHFTVDCT	EAGEGDVSVG	IKCDARVLSE	DEEDVDFDII
801	811	821	831	841	851	861	871	881	891
HNANDTFTVK	YVPPAAGRYT	IKVLFASQEI	PASPFRVKVD	PSHDASKVKA	EGPGLSKAGV	ENGKPTHFTV	YTKGAGKAPL	NVQFNSPLPG	DAVKDLDIID
901	911	921	931	941	951	961	971	981	991
NYDYSHTVKY	TPTQQGNMQV	LVTYGGDPIP	KSPFTVGVAA	PLDLSKIKLN	GLENRVEVGK	DQEFTVDTRG	AGGQGKLDVT	ILSPSRKVVP	CLVTPVTGRE
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
NSTAKFIPRE	EGLYAVDVTY	DGHPVPGSPY	TVEASLPPDP	SKVKAHGPGL	EGGLVGKPAE	FTIDTKGAGT	GGLGLTVEGP	CEAKIECSDN	GDGTCSVSYL
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
PTKPGEYFVN	ILFEEVHIPG	SPFKADIEMP	FDPSKVVASG	PGLEHGKVGE	AGLLSVDCSE	AGPGALGLEA	VSDSGTKAEV	SIQNNKDGTY	AVTYVPLTAG
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
MYTLTMKYGG	ELVPHFPARV	KVEPAVDTSR	IKVFGPGIEG	KDVFREATTD	FTVDSRPLTQ	VGGDHIKAHI	ANPSGASTEC	FVTDNADGTY	QVEYTPFEKG
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
LHVVEVTYDD	VPIPNSPFKV	AVTEGCQPSR	VQAQGPGLKE	AFTNKPNVFT	VVTRGAGIGG	LGITVEGPSE	SKINCRDNKD	GSCSAEYIPF	APGDYDVNIT
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
YGGAHIPGSP	FRVPVKDVVD	PSKVKIAGPG	LGSGVRARVL	QSFTVDSSKA	GLAPLEVRVL	GPRGLVEPVN	VVDNGDGTHT	VTYTPSQEGP	YMVSVKYADE
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
EIPRSPFKVK	VLPTYDASKV	TASGPGLSSY	GVPASLPVDF	AIDARDAGEG	LLAVQITDQE	GKPKRAIVHD	NKDGTYAVTY	IPDKTGRYMI	GVTYGGDDIP
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
LSPYRIRATQ	TGDASKCLAT	GPGIASTVKT	GEEVGFVVDA	KTAGKGKVTC	TVLTPDGTEA	EADVIENEDG	TYDIFYTAAK	PGTYVIYVRF	GGVDIPNSPF
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
TVMATDGEVT	AVEEAPVNAC	PPGFRPWVTE	EAYVPVSDMN	GLGFKPFDLV	IPFAVRKGEI	TGEVHMPSGK	TATPEIVDNK	DGTVTVRYAP	TEVGLHEMHI
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
KYMGSHIPES	PLQFYVNYPN	SGSVSAYGPG	LVYGVANKTA	TFTIVTEDAG	EGGLDLAIEG	PSKAEISCID	NKDGTCTVTY	LPTLPGDYSI	LVKYNDKHIP
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
GSPFTAKITD	DSRRCSQVKL	GSAADFLLDI	SETDLSSLTA	SIKAPSGRDE	PCLLKRLPNN	HIGISFIPRE	VGEHLVSIKK	NGNHVANSPV	SIMVVQSEIG
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
DARRAKVYGR	GLSEGRTFEM	SDFIVDTRDA	GYGGISLAVE	GPSKVDIQTE	DLEDGTCKVS	YFPTVPGVYI	VSTKFADEHV	PGSPFTVKIS	GEGRVKESIT
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
RTSRAPSVAT	VGSICDLNLK	IPEINSSDMS	AHVTSPSGRV	TEAEIVPMGK	NSHCVRFVPQ	EMGVHTVSVK	YRGQHVTGSP	FQFTVGPLGE	GGAHKVRAGG
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
PGLERGEAGV	PAEFSIWTRE	AGAGGLSIAV	EGPSKAEITF	DDHKNGSCGV	SYIAQEPGNY	EVSIKFNDEH	IPESPYLVPV	IAPSDDARRL	TVMSLQESGL
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
KVNQPASFAI	RLNGAKGKID	AKVHSPSGAV	EECHVSELEP	DKYAVRFIPH	ENGVHTIDVK	FNGSHVVGSP	FKVRVGEPGQ	AGNPALVSAY	GTGLEGGTTG
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
IQSEFFINTT	RAGPGTLSVT	IEGPSKVKMD	CQETPEGYKV	MYTPMAPGNY	LISVKYGGPN	HIVGSPFKAK	VTGQRLVSPG	SANETSSILV	ESVTRSSTET
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
CYSAIPKASS	DASKVTSKGA	GLSKAFVGQK	SSFLVDCSKA	GSNMLLIGVH	GPTTPCEEVS	MKHVGNQQYN	VTYVVKERGD	YVLAVKWGEE	HIPGSPFHVT
2601
VP

UniProtKB-O75369

Glycosites

Sequence

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
68	Zhang L, Xu Y, Yao H, Xie L, Yao J, Lu H, Yang P: Boronic Acid Functionalized Core-Satellite Composite Nanoparticles for Advanced Enrichment of Glycopeptides and Glycoproteins. Chemistry-a European Journal 2009, 15:10158-10166.