Detail

Contains

UniProtKB-O95980


Protein	Reversion-inducing cysteine-rich protein with Kazal motifs
Gene	RECK
Status	Reviewed
Source	Breast Cancer cell lines; Liver; OVCAR-3 cell line (Ovarian cancer); Prostate tumor; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
86	nSSLPGVFK	2015(1);
200	NYCASISPQLIHCVNnYTQSYPMR	2014(33);
297	HCCSKAnTSTCREL	2014(33);
352	CQIGCRnITYCTN	2013(37);
352	nLTYCTNFNNRPTELFR	2007(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MATVRASLRG	ALLLLLAVAG	VAEVAGGLAP	GSAGALCCNH	SKDNQMCRDV	CEQIFSSKSE	SRLKHLLQRA	PDYCPETMVE	IWNCMNSSLP	GVFKKSDGWV
101	111	121	131	141	151	161	171	181	191
GLGCCELAIA	LECRQACKQA	SSKNDISKVC	RKEYENALFS	CISRNEMGSV	CCSYAGHHTN	CREYCQAIFR	TDSSPGPSQI	KAVENYCASI	SPQLIHCVNN
201	211	221	231	241	251	261	271	281	291
YTQSYPMRNP	TDSLYCCDRA	EDHACQNACK	RILMSKKTEM	EIVDGLIEGC	KTQPLPQDPL	WQCFLESSQS	VHPGVTVHPP	PSTGLDGAKL	HCCSKANTST
301	311	321	331	341	351	361	371	381	391
CRELCTKLYS	MSWGNTQSWQ	EFDRFCEYNP	VEVSMLTCLA	DVREPCQLGC	RNLTYCTNFN	NRPTELFRSC	NAQSDQGAMN	DMKLWEKGSI	KMPFINIPVL
401	411	421	431	441	451	461	471	481	491
DIKKCQPEMW	KAIACSLQIK	PCHSKSRGSI	ICKSDCVEIL	KKCGDQNKFP	EDHTAESICE	LLSPTDDLKN	CIPLDTYLRP	STLGNIVEEV	THPCNPNPCP
501	511	521	531	541	551	561	571	581	591
ANELCEVNRK	GCPSGDPCLP	YFCVQGCKLG	EASDFIVRQG	TLIQVPSSAG	EVGCYKICSC	GQSGLLENCM	EMHCIDLQKS	CIVGGKRKSH	GTSFSIDCNV
601	611	621	631	641	651	661	671	681	691
CSCFAGNLVC	STRLCLSEHS	SEDDRRTFTG	LPCNCADQFV	PVCGQNGRTY	PSACIARCVG	LQDHQFEFGS	CMSKDPCNPN	PCQKNQRCIP	KPQVCLTTFD
701	711	721	731	741	751	761	771	781	791
KFGCSQYECV	PRQLACDQVQ	DPVCDTDHME	HNNLCTLYQR	GKSLSYKGPC	QPFCRATEPV	CGHNGETYSS	VCAAYSDRVA	VDYYGDCQAV	GVLSEHSSVA
801	811	821	831	841	851	861	871	881	891
ECASVKCPSL	LAAGCKPIIP	PGACCPLCAG	MLRVLFDKEK	LDTIAKVTNK	KPITVLEILQ	KIRMHVSVPQ	CDVFGYFSIE	SEIVILIIPV	DHYPKALQIE
901	911	921	931	941	951	961	971
ACNKEAEKIE	SLINSDSPTL	ASHVPLSALI	ISQVQVSSSV	PSAGVRARPS	CHSLLLPLSL	GLALHLLWTY	N

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.