| Protein | Coagulation factor VIII |
| Gene | F8 |
| Status | Reviewed |
| Source | Liver; Lung tumor; Plasma; Serum; Urine |
| Years | 2005-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 60 | SFPFnTSVVYK | 2015(10); |
| 601 | NVILFSVFDEnR | 2005(81); |
| 803 | IQnVSSSDLLMLLR | 2014(33); |
| 982 | LLESGLMNSQESSWGKnVSSTESGR | 2015(unpublished);2015(unpublished); |
| 1020 | DNALFKVSISLLKTnK | 2012(49); |
| 1074 | MLMDKnATALR | 2015(unpublished); |
| 1085 | LNHMSnK | 2015(10); |
| 1204 | NLFLTNLDNLHEnNTHNQEK | 2014(33); |
| 1301 | KGEEENLEGLGnQTK | 2014(33); 2015(10); |
| 1431 | QDnSSHLPAASY | 2014(33); |
| 1431 | VLFQDnSSHLPAASYR | 2014(33); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MQIELSTCFF | LCLLRFCFSA | TRRYYLGAVE | LSWDYMQSDL | GELPVDARFP | PRVPKSFPFN | TSVVYKKTLF | VEFTDHLFNI | AKPRPPWMGL | LGPTIQAEVY |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| DTVVITLKNM | ASHPVSLHAV | GVSYWKASEG | AEYDDQTSQR | EKEDDKVFPG | GSHTYVWQVL | KENGPMASDP | LCLTYSYLSH | VDLVKDLNSG | LIGALLVCRE |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| GSLAKEKTQT | LHKFILLFAV | FDEGKSWHSE | TKNSLMQDRD | AASARAWPKM | HTVNGYVNRS | LPGLIGCHRK | SVYWHVIGMG | TTPEVHSIFL | EGHTFLVRNH |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| RQASLEISPI | TFLTAQTLLM | DLGQFLLFCH | ISSHQHDGME | AYVKVDSCPE | EPQLRMKNNE | EAEDYDDDLT | DSEMDVVRFD | DDNSPSFIQI | RSVAKKHPKT |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| WVHYIAAEEE | DWDYAPLVLA | PDDRSYKSQY | LNNGPQRIGR | KYKKVRFMAY | TDETFKTREA | IQHESGILGP | LLYGEVGDTL | LIIFKNQASR | PYNIYPHGIT |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| DVRPLYSRRL | PKGVKHLKDF | PILPGEIFKY | KWTVTVEDGP | TKSDPRCLTR | YYSSFVNMER | DLASGLIGPL | LICYKESVDQ | RGNQIMSDKR | NVILFSVFDE |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| NRSWYLTENI | QRFLPNPAGV | QLEDPEFQAS | NIMHSINGYV | FDSLQLSVCL | HEVAYWYILS | IGAQTDFLSV | FFSGYTFKHK | MVYEDTLTLF | PFSGETVFMS |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| MENPGLWILG | CHNSDFRNRG | MTALLKVSSC | DKNTGDYYED | SYEDISAYLL | SKNNAIEPRS | FSQNSRHPST | RQKQFNATTI | PENDIEKTDP | WFAHRTPMPK |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| IQNVSSSDLL | MLLRQSPTPH | GLSLSDLQEA | KYETFSDDPS | PGAIDSNNSL | SEMTHFRPQL | HHSGDMVFTP | ESGLQLRLNE | KLGTTAATEL | KKLDFKVSST |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| SNNLISTIPS | DNLAAGTDNT | SSLGPPSMPV | HYDSQLDTTL | FGKKSSPLTE | SGGPLSLSEE | NNDSKLLESG | LMNSQESSWG | KNVSSTESGR | LFKGKRAHGP |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| ALLTKDNALF | KVSISLLKTN | KTSNNSATNR | KTHIDGPSLL | IENSPSVWQN | ILESDTEFKK | VTPLIHDRML | MDKNATALRL | NHMSNKTTSS | KNMEMVQQKK |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| EGPIPPDAQN | PDMSFFKMLF | LPESARWIQR | THGKNSLNSG | QGPSPKQLVS | LGPEKSVEGQ | NFLSEKNKVV | VGKGEFTKDV | GLKEMVFPSS | RNLFLTNLDN |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| LHENNTHNQE | KKIQEEIEKK | ETLIQENVVL | PQIHTVTGTK | NFMKNLFLLS | TRQNVEGSYD | GAYAPVLQDF | RSLNDSTNRT | KKHTAHFSKK | GEEENLEGLG |
| 1301 | 1311 | 1321 | 1331 | 1341 | 1351 | 1361 | 1371 | 1381 | 1391 |
| NQTKQIVEKY | ACTTRISPNT | SQQNFVTQRS | KRALKQFRLP | LEETELEKRI | IVDDTSTQWS | KNMKHLTPST | LTQIDYNEKE | KGAITQSPLS | DCLTRSHSIP |
| 1401 | 1411 | 1421 | 1431 | 1441 | 1451 | 1461 | 1471 | 1481 | 1491 |
| QANRSPLPIA | KVSSFPSIRP | IYLTRVLFQD | NSSHLPAASY | RKKDSGVQES | SHFLQGAKKN | NLSLAILTLE | MTGDQREVGS | LGTSATNSVT | YKKVENTVLP |
| 1501 | 1511 | 1521 | 1531 | 1541 | 1551 | 1561 | 1571 | 1581 | 1591 |
| KPDLPKTSGK | VELLPKVHIY | QKDLFPTETS | NGSPGHLDLV | EGSLLQGTEG | AIKWNEANRP | GKVPFLRVAT | ESSAKTPSKL | LDPLAWDNHY | GTQIPKEEWK |
| 1601 | 1611 | 1621 | 1631 | 1641 | 1651 | 1661 | 1671 | 1681 | 1691 |
| SQEKSPEKTA | FKKKDTILSL | NACESNHAIA | AINEGQNKPE | IEVTWAKQGR | TERLCSQNPP | VLKRHQREIT | RTTLQSDQEE | IDYDDTISVE | MKKEDFDIYD |
| 1701 | 1711 | 1721 | 1731 | 1741 | 1751 | 1761 | 1771 | 1781 | 1791 |
| EDENQSPRSF | QKKTRHYFIA | AVERLWDYGM | SSSPHVLRNR | AQSGSVPQFK | KVVFQEFTDG | SFTQPLYRGE | LNEHLGLLGP | YIRAEVEDNI | MVTFRNQASR |
| 1801 | 1811 | 1821 | 1831 | 1841 | 1851 | 1861 | 1871 | 1881 | 1891 |
| PYSFYSSLIS | YEEDQRQGAE | PRKNFVKPNE | TKTYFWKVQH | HMAPTKDEFD | CKAWAYFSDV | DLEKDVHSGL | IGPLLVCHTN | TLNPAHGRQV | TVQEFALFFT |
| 1901 | 1911 | 1921 | 1931 | 1941 | 1951 | 1961 | 1971 | 1981 | 1991 |
| IFDETKSWYF | TENMERNCRA | PCNIQMEDPT | FKENYRFHAI | NGYIMDTLPG | LVMAQDQRIR | WYLLSMGSNE | NIHSIHFSGH | VFTVRKKEEY | KMALYNLYPG |
| 2001 | 2011 | 2021 | 2031 | 2041 | 2051 | 2061 | 2071 | 2081 | 2091 |
| VFETVEMLPS | KAGIWRVECL | IGEHLHAGMS | TLFLVYSNKC | QTPLGMASGH | IRDFQITASG | QYGQWAPKLA | RLHYSGSINA | WSTKEPFSWI | KVDLLAPMII |
| 2101 | 2111 | 2121 | 2131 | 2141 | 2151 | 2161 | 2171 | 2181 | 2191 |
| HGIKTQGARQ | KFSSLYISQF | IIMYSLDGKK | WQTYRGNSTG | TLMVFFGNVD | SSGIKHNIFN | PPIIARYIRL | HPTHYSIRST | LRMELMGCDL | NSCSMPLGME |
| 2201 | 2211 | 2221 | 2231 | 2241 | 2251 | 2261 | 2271 | 2281 | 2291 |
| SKAISDAQIT | ASSYFTNMFA | TWSPSKARLH | LQGRSNAWRP | QVNNPKEWLQ | VDFQKTMKVT | GVTTQGVKSL | LTSMYVKEFL | ISSSQDGHQW | TLFFQNGKVK |
| 2301 | 2311 | 2321 | 2331 | 2341 | 2351 | ||||
| VFQGNQDSFT | PVVNSLDPPL | LTRYLRIHPQ | SWVHQIALRM | EVLGCEAQDL | Y |
| ID | Publication |
|---|---|
| 10 | Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 49 | Kim JY, Kim S-K, Kang D, Moon MH: Dual Lectin-Based Size Sorting Strategy to Enrich Targeted N-Glycopeptides by Asymmetrical Flow Field-Flow Fractionation: Profiling Lung Cancer Biomarkers. Analytical Chemistry 2012, 84:5343-5350. |
| 81 | Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Journal of Proteome Research 2005, 4:2070-2080. |