| Protein | Tissue-type plasminogen activator |
| Gene | PLAT |
| Status | Reviewed |
| Source | Breast Cancer cell lines; DRO-1 Cell Line (Thyroid Cance); HCC cell lines (Liver); Liver; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Prostate tumor; Urine |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 152 | AECTNWnSSAIAQ | 2013(37); |
| 152 | nSSALAQKPYSGR | 2015(1); |
| 152 | STAESGAECTNWnSSALAQKPY | 2014(33); |
| 152 | GTWSTAESGAECTNWnSSALAQKPYSGR | 2009(62); 2014(18); 2015(unpublished);2015;2007; |
| 219 | SDCYFGnGSAYRG | 2013(37); |
| 219 | GNSDCYFGnGSAYR | 2014(33); |
| 219 | YSSEFCSTPACSEGNSDCYFGnGSAYR | 2014(18); 2007(unpublished); |
| 219 | AGKYSSEFCSTPACSEGNSDCYFGnGSAYR | 2014(18); |
| 483 | CTSQHLLnR | 2013(40); 2014(33); |
| 483 | TSQHIInRTVTDN | 2013(37); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MDAMKRGLCC | VLLLCGAVFV | SPSQEIHARF | RRGARSYQVI | CRDEKTQMIY | QQHQSWLRPV | LRSNRVEYCW | CNSGRAQCHS | VPVKSCSEPR | CFNGGTCQQA |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| LYFSDFVCQC | PEGFAGKCCE | IDTRATCYED | QGISYRGTWS | TAESGAECTN | WNSSALAQKP | YSGRRPDAIR | LGLGNHNYCR | NPDRDSKPWC | YVFKAGKYSS |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| EFCSTPACSE | GNSDCYFGNG | SAYRGTHSLT | ESGASCLPWN | SMILIGKVYT | AQNPSAQALG | LGKHNYCRNP | DGDAKPWCHV | LKNRRLTWEY | CDVPSCSTCG |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| LRQYSQPQFR | IKGGLFADIA | SHPWQAAIFA | KHRRSPGERF | LCGGILISSC | WILSAAHCFQ | ERFPPHHLTV | ILGRTYRVVP | GEEEQKFEVE | KYIVHKEFDD |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| DTYDNDIALL | QLKSDSSRCA | QESSVVRTVC | LPPADLQLPD | WTECELSGYG | KHEALSPFYS | ERLKEAHVRL | YPSSRCTSQH | LLNRTVTDNM | LCAGDTRSGG |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | |||
| PQANLHDACQ | GDSGGPLVCL | NDGRMTLVGI | ISWGLGCGQK | DVPGVYTKVT | NYLDWIRDNM | RP |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 18 | Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |
| 62 | Arcinas A, Yen T-Y, Kebebew E, Macher BA: Cell Surface and Secreted Protein Profiles of Human Thyroid Cancer Cell Lines Reveal Distinct Glycoprotein Patterns. Journal of Proteome Research 2009, 8:3958-3968. |