Detail

UniProtKB-P02461


Protein	Collagen alpha-1(III) chain
Gene	COL3A1
Status	Reviewed
Source	Breast cancer xenografts; HCC cell lines (Liver); Hela cell line (cervical cancer); Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian cancer cell lines; Ovarian tumor; Prostate tumor
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
389	AGAQGPPGPPGInGSPGGK	2014(33);
389	GEPGPQGHAGAQGPPGPPGInGSPGGKGE	2014(33);
389	GEPGPQGHAGAQGPPGPPGInGSPGGKGEMGPAGIPGAPGLMGAR	2014(33);
1037	nGSPGAPGAPGHPGPPGPVGPAGK	2014(33);
1037	GEnGSPGAPGAPGHPGPPGPVGPAGK	2014(33);
1037	GDRGEnGSPGAPGAPGHPGPPGPVGPAGK	2014(33);
1037	GEnGSPGAPGAPGHPGPPGPVGPAGKSGDRGE	2014(33);
1037	DGSPGGKGDRGEnGSPGAPGAPGHPGPPGPVGPAGK	2014(33);
1367	nITYHCK	2015(1);
1367	ASQnITYHCK	2013(34); 2013(40); 2014(32); 2014(33); 2015(12); 2015(unpublished);2007(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MMSFVQKGSW	LLLALLHPTI	ILAQQEAVEG	GCSHLGQSYA	DRDVWKPEPC	QICVCDSGSV	LCDDIICDDQ	ELDCPNPEIP	FGECCAVCPQ	PPTAPTRPPN
101	111	121	131	141	151	161	171	181	191
GQGPQGPKGD	PGPPGIPGRN	GDPGIPGQPG	SPGSPGPPGI	CESCPTGPQN	YSPQYDSYDV	KSGVAVGGLA	GYPGPAGPPG	PPGPPGTSGH	PGSPGSPGYQ
201	211	221	231	241	251	261	271	281	291
GPPGEPGQAG	PSGPPGPPGA	IGPSGPAGKD	GESGRPGRPG	ERGLPGPPGI	KGPAGIPGFP	GMKGHRGFDG	RNGEKGETGA	PGLKGENGLP	GENGAPGPMG
301	311	321	331	341	351	361	371	381	391
PRGAPGERGR	PGLPGAAGAR	GNDGARGSDG	QPGPPGPPGT	AGFPGSPGAK	GEVGPAGSPG	SNGAPGQRGE	PGPQGHAGAQ	GPPGPPGING	SPGGKGEMGP
401	411	421	431	441	451	461	471	481	491
AGIPGAPGLM	GARGPPGPAG	ANGAPGLRGG	AGEPGKNGAK	GEPGPRGERG	EAGIPGVPGA	KGEDGKDGSP	GEPGANGLPG	AAGERGAPGF	RGPAGPNGIP
501	511	521	531	541	551	561	571	581	591
GEKGPAGERG	APGPAGPRGA	AGEPGRDGVP	GGPGMRGMPG	SPGGPGSDGK	PGPPGSQGES	GRPGPPGPSG	PRGQPGVMGF	PGPKGNDGAP	GKNGERGGPG
601	611	621	631	641	651	661	671	681	691
GPGPQGPPGK	NGETGPQGPP	GPTGPGGDKG	DTGPPGPQGL	QGLPGTGGPP	GENGKPGEPG	PKGDAGAPGA	PGGKGDAGAP	GERGPPGLAG	APGLRGGAGP
701	711	721	731	741	751	761	771	781	791
PGPEGGKGAA	GPPGPPGAAG	TPGLQGMPGE	RGGLGSPGPK	GDKGEPGGPG	ADGVPGKDGP	RGPTGPIGPP	GPAGQPGDKG	EGGAPGLPGI	AGPRGSPGER
801	811	821	831	841	851	861	871	881	891
GETGPPGPAG	FPGAPGQNGE	PGGKGERGAP	GEKGEGGPPG	VAGPPGGSGP	AGPPGPQGVK	GERGSPGGPG	AAGFPGARGL	PGPPGSNGNP	GPPGPSGSPG
901	911	921	931	941	951	961	971	981	991
KDGPPGPAGN	TGAPGSPGVS	GPKGDAGQPG	EKGSPGAQGP	PGAPGPLGIA	GITGARGLAG	PPGMPGPRGS	PGPQGVKGES	GKPGANGLSG	ERGPPGPQGL
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
PGLAGTAGEP	GRDGNPGSDG	LPGRDGSPGG	KGDRGENGSP	GAPGAPGHPG	PPGPVGPAGK	SGDRGESGPA	GPAGAPGPAG	SRGAPGPQGP	RGDKGETGER
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
GAAGIKGHRG	FPGNPGAPGS	PGPAGQQGAI	GSPGPAGPRG	PVGPSGPPGK	DGTSGHPGPI	GPPGPRGNRG	ERGSEGSPGH	PGQPGPPGPP	GAPGPCCGGV
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
GAAAIAGIGG	EKAGGFAPYY	GDEPMDFKIN	TDEIMTSLKS	VNGQIESLIS	PDGSRKNPAR	NCRDLKFCHP	ELKSGEYWVD	PNQGCKLDAI	KVFCNMETGE
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
TCISANPLNV	PRKHWWTDSS	AEKKHVWFGE	SMDGGFQFSY	GNPELPEDVL	DVHLAFLRLL	SSRASQNITY	HCKNSIAYMD	QASGNVKKAL	KLMGSNEGEF
1401	1411	1421	1431	1441	1451	1461
KAEGNSKFTY	TVLEDGCTKH	TGEWSKTVFE	YRTRKAVRLP	IVDIAPYDIG	GPDQEFGVDV	GPVCFL

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
32	Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.