| Protein | Serine protease hepsin |
| Gene | HPN |
| Status | Reviewed |
| Source | Breast cancer xenografts; Liver; Liver tumor (HCC); OVCAR-3 cell line (Ovarian cancer); Urine |
| Years | 2009-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 112 | TAGAnGTSGFF | 2014(33); |
| 112 | DVRTAGAnGTSGF | 2009(64); 2014(33); |
| 112 | DVRTAGAnGTSGFF | 2014(33); |
| 112 | TAGAnGTSGFFCVDE | 2014(33); |
| 112 | TAGAnGTSGFFCVDEGR | 2014(32); 2014(32); 2014(33); 2015(1); 2015(unpublished);2015(unpublished);2015(unpublished); |
| 112 | THSELDVRTAGAnGTSGF | 2014(33); |
| 112 | THSELDVRTAGAnGTSGFF | 2014(33); |
| 112 | TAGAnGTSGFFCVDEGRLPHTQR | 2014(33); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MAQKEGGRTV | PCCSRPKVAA | LTAGTLLLLT | AIGAASWAIV | AVLLRSDQEP | LYPVQVSSAD | ARLMVFDKTE | GTWRLLCSSR | SNARVAGLSC | EEMGFLRALT |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| HSELDVRTAG | ANGTSGFFCV | DEGRLPHTQR | LLEVISVCDC | PRGRFLAAIC | QDCGRRKLPV | DRIVGGRDTS | LGRWPWQVSL | RYDGAHLCGG | SLLSGDWVLT |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| AAHCFPERNR | VLSRWRVFAG | AVAQASPHGL | QLGVQAVVYH | GGYLPFRDPN | SEENSNDIAL | VHLSSPLPLT | EYIQPVCLPA | AGQALVDGKI | CTVTGWGNTQ |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| YYGQQAGVLQ | EARVPIISND | VCNGADFYGN | QIKPKMFCAG | YPEGGIDACQ | GDSGGPFVCE | DSISRTPRWR | LCGIVSWGTG | CALAQKPGVY | TKVSDFREWI |
| 401 | 411 | ||||||||
| FQAIKTHSEA | SGMVTQL |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |