| Protein | Carcinoembryonic antigen-related cell adhesion molecule 5 |
| Gene | CEACAM5 |
| Status | Reviewed |
| Source | Breast Cancer cell lines; Breast cancer xenografts; Breast cell lines; Breast tumor; Colorectal tumor; Colorectal tumors; DLBCL cell lines (Diffuse large B-cell lymphoma); HCCLM3 cell line (Liver); LNCap/PC3 cell lines (Prostate cancer); Liver; Ovarian tumor; Prostate tumor; SW1990 cell line (Pancreatic cancer); Saliva; Urine; ovarian tumor |
| Years | 2006-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 104 | EIIYPnASLLIQNIIQNDTGFYTLHVIK | 2009(68); |
| 115 | EIIYPNASLLIQNIIQnDTGFYTLHVIK | 2009(68); |
| 152 | KPSISSnNSKPVE | 2013(37); |
| 182 | nQSLPVSPR | 2014(33); |
| 197 | SNGnRTL | 2014(33); |
| 197 | IQISNGnR | 2014(16); |
| 197 | LQLSNGnR | 2014(33); 2015(2); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished); |
| 197 | LSNGnRTL | 2014(33); |
| 197 | LQLSNGnRTL | 2014(33); |
| 197 | IQISNGnRTITIF | 2013(37); |
| 204 | TLTLFnVTR | 2006( 77); 2007(63); 2009(47); 2012(52); 2012(22); 2014(2); 2015(unpublished);2015(unpublished);2015;2015;2007;2007; |
| 204 | IFnVTRNDTASYK | 2013(37); |
| 204 | RTITIFnVTRNDT | 2013(37); |
| 204 | TLTLFnVTRNDTASYK | 2009(63); 2015(2); 2015(unpublished);2015(unpublished); |
| 208 | IFNVTRnDTASYK | 2013(37); |
| 208 | RTITIFNVTRnDT | 2013(37); |
| 208 | TLTLFNVTRnDTASYK | 2009(63); 2015(2); 2015(unpublished);2015(unpublished); |
| 246 | PTISPInTSYRSG | 2013(37); |
| 246 | SDSVILNVLYGPDAPTISPLnTSYR | 2007(63); 2009(2); 2015(unpublished);2007(unpublished);2007; |
| 246 | RSDSVILNVLYGPDAPTISPLnTSYR | 2009(64); 2009(68); 2012(52); 2015(2); |
| 288 | IPnITVNNSGSY | 2014(33); |
| 288 | FIPnITVNNSGSY | 2014(33); |
| 288 | LFIPnITVNNSGSY | 2014(33); |
| 288 | ELFIPnITVNNSGSY | 2014(33); |
| 288 | QQSTQELFIPnITVNNSGSY | 2014(33); |
| 292 | IPNITVnNSGSY | 2014(33); |
| 292 | FIPNITVnNSGSY | 2014(33); |
| 292 | LFIPNITVnNSGSY | 2014(33); |
| 292 | ELFIPNITVnNSGSY | 2014(33); |
| 292 | QQSTQELFIPNITVnNSGSY | 2014(33); |
| 360 | nQSLPVSPR | 2014(33); |
| 375 | LQLSNDnR | 2014(22); 2015(2); 2015(unpublished);2015(unpublished);2015(unpublished); |
| 375 | IQISNDnRTITII | 2013(37); |
| 375 | LQLSNDnRTLTLLSVTR | 2015(2); |
| 466 | TQELFISnITEK | 2007(unpublished);2007(unpublished); |
| 480 | IYTCQAnNSASGH | 2013(37); |
| 480 | NSGLYTCQAnNSASGHSR | 2015(2); 2015(3); 2015(unpublished);2015;2015;2007; |
| 508 | KPSISSnNSKPVE | 2013(37); |
| 529 | DAVAFTCEPEAQnTTYLWWVN | 2007(unpublished); |
| 553 | SNGnRTL | 2014(33); |
| 553 | IQISNGnR | 2014(16); |
| 553 | LQLSNGnR | 2014(33); 2015(2); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished); |
| 553 | LSNGnRTL | 2014(33); |
| 553 | LQLSNGnRTL | 2014(33); |
| 553 | IQISNGnRTITIF | 2013(37); |
| 560 | TLTLFnVTR | 2006( 77); 2007(63); 2009(47); 2012(52); 2012(22); 2014(2); 2015(unpublished);2015(unpublished);2015;2015;2007;2007; |
| 580 | SAnRSDPVTL | 2014(33); |
| 580 | QNSVSAnRSDPVT | 2013(37); |
| 580 | AYVCGIQNSVSAnR | 2007(54); 2011(52); 2012(22); 2014(unpublished);2015(unpublished);2007(unpublished);2007;2007; |
| 650 | KITPNNnGTYACF | 2013(37); |
| 650 | ITPNNnGTYACFVSNLATGR | 2007(54); 2011(52); 2012(22); 2014(2); 2015(unpublished);2007(unpublished);2007(unpublished);2007; |
| 665 | nNSIVK | 2015(2); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MESPSAPPHR | WCIPWQRLLL | TASLLTFWNP | PTTAKLTIES | TPFNVAEGKE | VLLLVHNLPQ | HLFGYSWYKG | ERVDGNRQII | GYVIGTQQAT | PGPAYSGREI |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| IYPNASLLIQ | NIIQNDTGFY | TLHVIKSDLV | NEEATGQFRV | YPELPKPSIS | SNNSKPVEDK | DAVAFTCEPE | TQDATYLWWV | NNQSLPVSPR | LQLSNGNRTL |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| TLFNVTRNDT | ASYKCETQNP | VSARRSDSVI | LNVLYGPDAP | TISPLNTSYR | SGENLNLSCH | AASNPPAQYS | WFVNGTFQQS | TQELFIPNIT | VNNSGSYTCQ |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| AHNSDTGLNR | TTVTTITVYA | EPPKPFITSN | NSNPVEDEDA | VALTCEPEIQ | NTTYLWWVNN | QSLPVSPRLQ | LSNDNRTLTL | LSVTRNDVGP | YECGIQNKLS |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| VDHSDPVILN | VLYGPDDPTI | SPSYTYYRPG | VNLSLSCHAA | SNPPAQYSWL | IDGNIQQHTQ | ELFISNITEK | NSGLYTCQAN | NSASGHSRTT | VKTITVSAEL |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| PKPSISSNNS | KPVEDKDAVA | FTCEPEAQNT | TYLWWVNGQS | LPVSPRLQLS | NGNRTLTLFN | VTRNDARAYV | CGIQNSVSAN | RSDPVTLDVL | YGPDTPIISP |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| PDSSYLSGAN | LNLSCHSASN | PSPQYSWRIN | GIPQQHTQVL | FIAKITPNNN | GTYACFVSNL | ATGRNNSIVK | SITVSASGTS | PGLSAGATVG | IMIGVLVGVA |
| 701 | |||||||||
| LI |
| ID | Publication |
|---|---|
| 2 | Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763. |
| 3 | Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H: Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical proteomics 2015, 12:11. |
| 16 | Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 47 | Almaraz RT, Tian Y, Bhattarcharya R, Tan E, Chen S-H, Dallas MR, Chen L, Zhang Z, Zhang H, Konstantopoulos K: Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis. Molecular & Cellular Proteomics 2012, 11:M112. 017558. |
| 52 | Yen T-Y, Macher BA, McDonald CA, Alleyne-Chin C, Timpe LC: Glycoprotein Profiles of Human Breast Cells Demonstrate a Clear Clustering of Normal/Benign versus Malignant Cell Lines and Basal versus Luminal Cell Lines. Journal of Proteome Research 2012, 11:656-667. |
| 54 | Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687. |
| 63 | Cao J, Shen C, Wang H, Shen H, Chen Y, Nie A, Yan G, Lu H, Liu Y, Yang P: Identification of N-Glycosylation Sites on Secreted Proteins of Human Hepatocellular Carcinoma Cells with a Complementary Proteomics Approach. Journal of Proteome Research 2009, 8:662-672. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |
| 68 | Zhang L, Xu Y, Yao H, Xie L, Yao J, Lu H, Yang P: Boronic Acid Functionalized Core-Satellite Composite Nanoparticles for Advanced Enrichment of Glycopeptides and Glycoproteins. Chemistry-a European Journal 2009, 15:10158-10166. |