Contains      

UniProtKB-P08697

Protein Alpha-2-antiplasmin
Gene SERPINF2
Status Reviewed
Source Bladder tumor; Breast tumor; Cerebrospinal fluid; HuH-7 cell line (Liver); Liver; Ovarian tumor; Plasma; Prostate; Prostate tumor; Serum; Serum (Colorectal cancer); Urine
Years 2005-2015

Glycosites

Site Identified Peptides Year(Publication ID)
126 AQnHTLQR 2007(unpublished);2007(unpublished);2007(unpublished);2007(unpublished);2007(unpublished);2007 (Unpublished );
126 GAQnHTLQ 2014(33);
126 ALGAQnHTL 2014(33);
126 GAQnHTLQR 2014(14);
126 ALGAQnHTLQ 2014(33);
126 LGAQnHTLQR 2007(unpublished);
126 ALGAQnHTLQR 2014(14);
126 ALGAQnHTLQRL 2014(33);
126 LALGAQnHTLQR 2015(unpublished);
126 ALSHLALGAQnHTL 2014(33);
126 SHLALGAQnHTLQR 2015(unpublished);
126 ALSHLALGAQnHTLQR 2014(21); 2015(unpublished);
126 ALALSHLALGAQnHTLQR 2015(unpublished);
126 SVALALSHLALGAQnHTLQR 2005(81); 2015(unpublished);
126 LILSPLSVALALSHLALGAQnHTLQR 2015(unpublished);
126 AMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQnHTLQR 2014(35);
295 KNnMSFVVLVPTHF 2014(33);
295 NnMSFVVLVPTHFE 2014(33);
295 NnMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTK 2005(81); 2013(38); 2014(35); 2015(unpublished);
309 NNMSFVVLVPTHFEWnVSQVLANLSWDTLHPPLVWERPTK 2005(81); 2013(38); 2014(35); 2015(unpublished);
316 AnLSWDTLHPPLVWERPTK 2007(unpublished);2007(unpublished);2007;
316 NNMSFVVLVPTHFEWNVSQVLAnLSWDTLHPPLVWERPTK 2005(81); 2013(38); 2014(35); 2015(unpublished);

Sequence

1112131415161718191
MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQT
101111121131141151161171181191
STCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDD
201211221231241251261271281291
LANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVV
301311321331341351361371381391
LVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIA
401411421431441451461471481491
MSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK

Reference

ID Publication
14Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
21Liu L, Yu M, Zhang Y, Wang C, Lu H: Hydrazide Functionalized Core-Shell Magnetic Nanocomposites for Highly Specific Enrichment of N-Glycopeptides. Acs Applied Materials & Interfaces 2014, 6:7823-7832.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
35Chen J, Shah P, Zhang H: Solid phase extraction of N-linked glycopeptides using hydrazide tip. Analytical chemistry 2013, 85:10670-10674.
38Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640.
81Liu T, Qian WJ, Gritsenko MA, Camp DG, Monroe ME, Moore RJ, Smith RD: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Journal of Proteome Research 2005, 4:2070-2080.