Detail

UniProtKB-P14410


Protein	Sucrase-isomaltase, intestinal
Gene	SI
Status	Reviewed
Source	Colorectal tumor; LNCap/PC3 cell lines (Prostate cancer); Ovarian tumor; Prostate; Prostate tumor; Serum; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
437	AnGTTYATYER	2014(22); 2007(unpublished);2007(unpublished);
823	KNPLGLIVALGEnNTAK	2015(unpublished);2015(unpublished);
1235	YGYAnTSEVR	2014(14); 2014(22); 2015(unpublished);2015(unpublished);
1303	YIIILDPAISGnETK	2015(2); 2015(unpublished);2015(unpublished);
1303	IRGEGMRYIIILDPAISGnETK	2013(42);
1354	TLTEDEAVnASR	2014(14); 2014(22); 2015(2); 2015(unpublished);2015(unpublished);2015;2015;2007;2007;
1675	GQFQTFnASYDTINLHVR	2015(2); 2015(unpublished);2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MARKKFSGLE	ISLIVLFVIV	TIIAIALIVV	LATKTPAVDE	ISDSTSTPAT	TRVTTNPSDS	GKCPNVLNDP	VNVRINCIPE	QFPTEGICAQ	RGCCWRPWND
101	111	121	131	141	151	161	171	181	191
SLIPWCFFVD	NHGYNVQDMT	TTSIGVEAKL	NRIPSPTLFG	NDINSVLFTT	QNQTPNRFRF	KITDPNNRRY	EVPHQYVKEF	TGPTVSDTLY	DVKVAQNPFS
201	211	221	231	241	251	261	271	281	291
IQVIRKSNGK	TLFDTSIGPL	VYSDQYLQIS	TRLPSDYIYG	IGEQVHKRFR	HDLSWKTWPI	FTRDQLPGDN	NNNLYGHQTF	FMCIEDTSGK	SFGVFLMNSN
301	311	321	331	341	351	361	371	381	391
AMEIFIQPTP	IVTYRVTGGI	LDFYILLGDT	PEQVVQQYQQ	LVGLPAMPAY	WNLGFQLSRW	NYKSLDVVKE	VVRRNREAGI	PFDTQVTDID	YMEDKKDFTY
401	411	421	431	441	451	461	471	481	491
DQVAFNGLPQ	FVQDLHDHGQ	KYVIILDPAI	SIGRRANGTT	YATYERGNTQ	HVWINESDGS	TPIIGEVWPG	LTVYPDFTNP	NCIDWWANEC	SIFHQEVQYD
501	511	521	531	541	551	561	571	581	591
GLWIDMNEVS	SFIQGSTKGC	NVNKLNYPPF	TPDILDKLMY	SKTICMDAVQ	NWGKQYDVHS	LYGYSMAIAT	EQAVQKVFPN	KRSFILTRST	FAGSGRHAAH
601	611	621	631	641	651	661	671	681	691
WLGDNTASWE	QMEWSITGML	EFSLFGIPLV	GADICGFVAE	TTEELCRRWM	QLGAFYPFSR	NHNSDGYEHQ	DPAFFGQNSL	LVKSSRQYLT	IRYTLLPFLY
701	711	721	731	741	751	761	771	781	791
TLFYKAHVFG	ETVARPVLHE	FYEDTNSWIE	DTEFLWGPAL	LITPVLKQGA	DTVSAYIPDA	IWYDYESGAK	RPWRKQRVDM	YLPADKIGLH	LRGGYIIPIQ
801	811	821	831	841	851	861	871	881	891
EPDVTTTASR	KNPLGLIVAL	GENNTAKGDF	FWDDGETKDT	IQNGNYILYT	FSVSNNTLDI	VCTHSSYQEG	TTLAFQTVKI	LGLTDSVTEV	RVAENNQPMN
901	911	921	931	941	951	961	971	981	991
AHSNFTYDAS	NQVLLIADLK	LNLGRNFSVQ	WNQIFSENER	FNCYPDADLA	TEQKCTQRGC	VWRTGSSLSK	APECYFPRQD	NSYSVNSARY	SSMGITADLQ
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
LNTANARIKL	PSDPISTLRV	EVKYHKNDML	QFKIYDPQKK	RYEVPVPLNI	PTTPISTYED	RLYDVEIKEN	PFGIQIRRRS	SGRVIWDSWL	PGFAFNDQFI
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
QISTRLPSEY	IYGFGEVEHT	AFKRDLNWNT	WGMFTRDQPP	GYKLNSYGFH	PYYMALEEEG	NAHGVFLLNS	NAMDVTFQPT	PALTYRTVGG	ILDFYMFLGP
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
TPEVATKQYH	EVIGHPVMPA	YWALGFQLCR	YGYANTSEVR	ELYDAMVAAN	IPYDVQYTDI	DYMERQLDFT	IGEAFQDLPQ	FVDKIRGEGM	RYIIILDPAI
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
SGNETKTYPA	FERGQQNDVF	VKWPNTNDIC	WAKVWPDLPN	ITIDKTLTED	EAVNASRAHV	AFPDFFRTST	AEWWAREIVD	FYNEKMKFDG	LWIDMNEPSS
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
FVNGTTTNQC	RNDELNYPPY	FPELTKRTDG	LHFRTICMEA	EQILSDGTSV	LHYDVHNLYG	WSQMKPTHDA	LQKTTGKRGI	VISRSTYPTS	GRWGGHWLGD
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
NYARWDNMDK	SIIGMMEFSL	FGMSYTGADI	CGFFNNSEYH	LCTRWMQLGA	FYPYSRNHNI	ANTRRQDPAS	WNETFAEMSR	NILNIRYTLL	PYFYTQMHEI
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
HANGGTVIRP	LLHEFFDEKP	TWDIFKQFLW	GPAFMVTPVL	EPYVQTVNAY	VPNARWFDYH	TGKDIGVRGQ	FQTFNASYDT	INLHVRGGHI	LPCQEPAQNT
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
FYSRQKHMKL	IVAADDNQMA	QGSLFWDDGE	SIDTYERDLY	LSVQFNLNQT	TLTSTILKRG	YINKSETRLG	SLHVWGKGTT	PVNAVTLTYN	GNKNSLPFNE
1801	1811	1821
DTTNMILRID	LTTHNVTLEE	PIEINWS

Reference

ID	Publication
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
42	Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450.