UniProtKB-P15514

Protein Amphiregulin
Gene AREG
Status Reviewed
Source Breast Cancer cell lines; HCC cell lines (Liver); Human; Jurkat T cell line; Urine
Years 2013-2015

Glycosites

Site Identified Peptides Year(Publication ID)
113 VEQVVKPPQnK 2013(40); 2014(13); 2015(unpublished);2015(unpublished);2015(unpublished);
113 VVKPPQnKTESEN 2013(37);
113 KPPQnKTESENTSDKPKRKK 2015(6);
113 VEQVVKPPQnKTESENTSDKPK 2014(13);
119 KPPQNKTESEnTSDKPKRKK 2015(6);
119 VEQVVKPPQNKTESEnTSDKPK 2014(13);

Sequence

1112131415161718191
MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDD
101111121131141151161171181191
SVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSKIA
201211221231241251
LAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKKLRQENGNVHAIA

Reference

ID Publication
6Kim DS, Hahn Y: The acquisition of novel N-glycosylation sites in conserved proteins during human evolution. Bmc Bioinformatics 2015, 16.
13Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
37Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
40Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.