| Protein | Desmoplakin |
| Gene | DSP |
| Status | Reviewed |
| Source | HCC cell lines (Liver); Liver; OVCAR-3 cell line (Ovarian cancer); Prostate tumor; Serum; Urine |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 1215 | YETEInITK | 2015(unpublished);2015(unpublished); |
| 1614 | ITnLTQQLEQASIVK | 2007(42); 2013(unpublished);2007(unpublished);2007; |
| 2423 | nLTYLQLK | 2015(1); |
| 2423 | GFFDPNTEEnLTYLQLK | 2013(40); |
| 2601 | nITIR | 2014(33); |
| 2601 | nITLR | 2014(33); |
| 2601 | nLTIR | 2014(33); |
| 2601 | nLTLR | 2014(33); |
| 2855 | nSSYSYSYSFSSSSIGH | 2015(1); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MSCNGGSHPR | INTLGRMIRA | ESGPDLRYEV | TSGGGGTSRM | YYSRRGVITD | QNSDGYCQTG | TMSRHQNQNT | IQELLQNCSD | CLMRAELIVQ | PELKYGDGIQ |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| LTRSRELDEC | FAQANDQMEI | LDSLIREMRQ | MGQPCDAYQK | RLLQLQEQMR | ALYKAISVPR | VRRASSKGGG | GYTCQSGSGW | DEFTKHVTSE | CLGWMRQQRA |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| EMDMVAWGVD | LASVEQHINS | HRGIHNSIGD | YRWQLDKIKA | DLREKSAIYQ | LEEEYENLLK | ASFERMDHLR | QLQNIIQATS | REIMWINDCE | EEELLYDWSD |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| KNTNIAQKQE | AFSIRMSQLE | VKEKELNKLK | QESDQLVLNQ | HPASDKIEAY | MDTLQTQWSW | ILQITKCIDV | HLKENAAYFQ | FFEEAQSTEA | YLKGLQDSIR |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| KKYPCDKNMP | LQHLLEQIKE | LEKEREKILE | YKRQVQNLVN | KSKKIVQLKP | RNPDYRSNKP | IILRALCDYK | QDQKIVHKGD | ECILKDNNER | SKWYVTGPGG |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| VDMLVPSVGL | IIPPPNPLAV | DLSCKIEQYY | EAILALWNQL | YINMKSLVSW | HYCMIDIEKI | RAMTIAKLKT | MRQEDYMKTI | ADLELHYQEF | IRNSQGSEMF |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| GDDDKRKIQS | QFTDAQKHYQ | TLVIQLPGYP | QHQTVTTTEI | THHGTCQDVN | HNKVIETNRE | NDKQETWMLM | ELQKIRRQIE | HCEGRMTLKN | LPLADQGSSH |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| HITVKINELK | SVQNDSQAIA | EVLNQLKDML | ANFRGSEKYC | YLQNEVFGLF | QKLENINGVT | DGYLNSLCTV | RALLQAILQT | EDMLKVYEAR | LTEEETVCLD |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| LDKVEAYRCG | LKKIKNDLNL | KKSLLATMKT | ELQKAQQIHS | QTSQQYPLYD | LDLGKFGEKV | TQLTDRWQRI | DKQIDFRLWD | LEKQIKQLRN | YRDNYQAFCK |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| WLYDAKRRQD | SLESMKFGDS | NTVMRFLNEQ | KNLHSEISGK | RDKSEEVQKI | AELCANSIKD | YELQLASYTS | GLETLLNIPI | KRTMIQSPSG | VILQEAADVH |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| ARYIELLTRS | GDYYRFLSEM | LKSLEDLKLK | NTKIEVLEEE | LRLARDANSE | NCNKNKFLDQ | NLQKYQAECS | QFKAKLASLE | ELKRQAELDG | KSAKQNLDKC |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| YGQIKELNEK | ITRLTYEIED | EKRRRKSVED | RFDQQKNDYD | QLQKARQCEK | ENLGWQKLES | EKAIKEKEYE | IERLRVLLQE | EGTRKREYEN | ELAKVRNHYN |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| EEMSNLRNKY | ETEINITKTT | IKEISMQKED | DSKNLRNQLD | RLSRENRDLK | DEIVRLNDSI | LQATEQRRRA | EENALQQKAC | GSEIMQKKQH | LEIELKQVMQ |
| 1301 | 1311 | 1321 | 1331 | 1341 | 1351 | 1361 | 1371 | 1381 | 1391 |
| QRSEDNARHK | QSLEEAAKTI | QDKNKEIERL | KAEFQEEAKR | RWEYENELSK | VRNNYDEEII | SLKNQFETEI | NITKTTIHQL | TMQKEEDTSG | YRAQIDNLTR |
| 1401 | 1411 | 1421 | 1431 | 1441 | 1451 | 1461 | 1471 | 1481 | 1491 |
| ENRSLSEEIK | RLKNTLTQTT | ENLRRVEEDI | QQQKATGSEV | SQRKQQLEVE | LRQVTQMRTE | ESVRYKQSLD | DAAKTIQDKN | KEIERLKQLI | DKETNDRKCL |
| 1501 | 1511 | 1521 | 1531 | 1541 | 1551 | 1561 | 1571 | 1581 | 1591 |
| EDENARLQRV | QYDLQKANSS | ATETINKLKV | QEQELTRLRI | DYERVSQERT | VKDQDITRFQ | NSLKELQLQK | QKVEEELNRL | KRTASEDSCK | RKKLEEELEG |
| 1601 | 1611 | 1621 | 1631 | 1641 | 1651 | 1661 | 1671 | 1681 | 1691 |
| MRRSLKEQAI | KITNLTQQLE | QASIVKKRSE | DDLRQQRDVL | DGHLREKQRT | QEELRRLSSE | VEALRRQLLQ | EQESVKQAHL | RNEHFQKAIE | DKSRSLNESK |
| 1701 | 1711 | 1721 | 1731 | 1741 | 1751 | 1761 | 1771 | 1781 | 1791 |
| IEIERLQSLT | ENLTKEHLML | EEELRNLRLE | YDDLRRGRSE | ADSDKNATIL | ELRSQLQISN | NRTLELQGLI | NDLQRERENL | RQEIEKFQKQ | ALEASNRIQE |
| 1801 | 1811 | 1821 | 1831 | 1841 | 1851 | 1861 | 1871 | 1881 | 1891 |
| SKNQCTQVVQ | ERESLLVKIK | VLEQDKARLQ | RLEDELNRAK | STLEAETRVK | QRLECEKQQI | QNDLNQWKTQ | YSRKEEAIRK | IESEREKSER | EKNSLRSEIE |
| 1901 | 1911 | 1921 | 1931 | 1941 | 1951 | 1961 | 1971 | 1981 | 1991 |
| RLQAEIKRIE | ERCRRKLEDS | TRETQSQLET | ERSRYQREID | KLRQRPYGSH | RETQTECEWT | VDTSKLVFDG | LRKKVTAMQL | YECQLIDKTT | LDKLLKGKKS |
| 2001 | 2011 | 2021 | 2031 | 2041 | 2051 | 2061 | 2071 | 2081 | 2091 |
| VEEVASEIQP | FLRGAGSIAG | ASASPKEKYS | LVEAKRKKLI | SPESTVMLLE | AQAATGGIID | PHRNEKLTVD | SAIARDLIDF | DDRQQIYAAE | KAITGFDDPF |
| 2101 | 2111 | 2121 | 2131 | 2141 | 2151 | 2161 | 2171 | 2181 | 2191 |
| SGKTVSVSEA | IKKNLIDRET | GMRLLEAQIA | SGGVVDPVNS | VFLPKDVALA | RGLIDRDLYR | SLNDPRDSQK | NFVDPVTKKK | VSYVQLKERC | RIEPHTGLLL |
| 2201 | 2211 | 2221 | 2231 | 2241 | 2251 | 2261 | 2271 | 2281 | 2291 |
| LSVQKRSMSF | QGIRQPVTVT | ELVDSGILRP | STVNELESGQ | ISYDEVGERI | KDFLQGSSCI | AGIYNETTKQ | KLGIYEAMKI | GLVRPGTALE | LLEAQAATGF |
| 2301 | 2311 | 2321 | 2331 | 2341 | 2351 | 2361 | 2371 | 2381 | 2391 |
| IVDPVSNLRL | PVEEAYKRGL | VGIEFKEKLL | SAERAVTGYN | DPETGNIISL | FQAMNKELIE | KGHGIRLLEA | QIATGGIIDP | KESHRLPVDI | AYKRGYFNEE |
| 2401 | 2411 | 2421 | 2431 | 2441 | 2451 | 2461 | 2471 | 2481 | 2491 |
| LSEILSDPSD | DTKGFFDPNT | EENLTYLQLK | ERCIKDEETG | LCLLPLKEKK | KQVQTSQKNT | LRKRRVVIVD | PETNKEMSVQ | EAYKKGLIDY | ETFKELCEQE |
| 2501 | 2511 | 2521 | 2531 | 2541 | 2551 | 2561 | 2571 | 2581 | 2591 |
| CEWEEITITG | SDGSTRVVLV | DRKTGSQYDI | QDAIDKGLVD | RKFFDQYRSG | SLSLTQFADM | ISLKNGVGTS | SSMGSGVSDD | VFSSSRHESV | SKISTISSVR |
| 2601 | 2611 | 2621 | 2631 | 2641 | 2651 | 2661 | 2671 | 2681 | 2691 |
| NLTIRSSSFS | DTLEESSPIA | AIFDTENLEK | ISITEGIERG | IVDSITGQRL | LEAQACTGGI | IHPTTGQKLS | LQDAVSQGVI | DQDMATRLKP | AQKAFIGFEG |
| 2701 | 2711 | 2721 | 2731 | 2741 | 2751 | 2761 | 2771 | 2781 | 2791 |
| VKGKKKMSAA | EAVKEKWLPY | EAGQRFLEFQ | YLTGGLVDPE | VHGRISTEEA | IRKGFIDGRA | AQRLQDTSSY | AKILTCPKTK | LKISYKDAIN | RSMVEDITGL |
| 2801 | 2811 | 2821 | 2831 | 2841 | 2851 | 2861 | 2871 | ||
| RLLEAASVSS | KGLPSPYNMS | SAPGSRSGSR | SGSRSGSRSG | SRSGSRRGSF | DATGNSSYSY | SYSFSSSSIG | H |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |
| 42 | Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450. |