| Protein | Platelet endothelial cell adhesion molecule |
| Gene | PECAM1 |
| Status | Reviewed |
| Source | Breast tumor; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); HCC cell lines (Liver); Jurkat T cell line; Liver; Liver tumor (HCC); Lymphocytes; Ovarian tumor; Pancreatic islets; Pancreatic isletsJurkat T cell line; Platelet; Platelet Plasma membranes; Prostate; Prostate tumor; Serum; Urine; UrineJurkat T cell line |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 52 | nLTLQCFADVSTTSHVKPQHQML | 2007(unpublished);2007(unpublished);2007; |
| 84 | nISSMKSTESY | 2014(33); |
| 84 | DDVIFYnISSMK | 2014(16); 2014(32); 2014(32); |
| 84 | DDVLFYnISSMK | 2007(74); 2012(3); 2012(48); 2013(45); 2014(13); 2014(14); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015;2015;2007;2007;2007;2007; |
| 84 | YKDDVLFYnISSMK | 2007(unpublished);2012(48); 2015(unpublished); |
| 151 | VnCSVPEEK | 2007(74); 2007(48); 2012(40); 2013(45); 2013(13); 2014(16); 2014(22); 2014(33); 2014(unpublished);2015(unpublished);2015;2015;2015;2015;2007;2007; |
| 151 | VnCSVPEEKAP | 2009(64); |
| 151 | VnCSVPEEKAPIHFTIEK | 2015(unpublished); |
| 151 | VnCSVPEEKAPIHFTIEKLELNEK | 2014(33); |
| 151 | DKKEAIQGGIVRVnCSVPEEKAPIHF | 2014(33); |
| 301 | HSGnYTCKVE | 2014(33); |
| 301 | AMVEHSGnYTCK | 2012(48); |
| 301 | SVMAMVEHSGnY | 2014(33); |
| 301 | SVMAMVEHSGnYTCK | 2014(33); |
| 301 | AVYSVMAMVEHSGnYTCK | 2014(13); 2015(unpublished); |
| 320 | VSSIVVnITE | 2014(33); |
| 320 | VSSIVVnITELFSKPELESSFTHLDQGER | 2009(64); 2014(33); 2015(unpublished);2015(unpublished);2007;2007; |
| 344 | LnLSCSIPGAPPANFTIQK | 2007(74); 2014(22); 2015(unpublished);2015(unpublished); |
| 356 | LNLSCSIPGAPPAnFTIQK | 2007(74); 2014(22); 2015(unpublished);2015(unpublished); |
| 453 | VLEnSTK | 2007(74); 2013(40); 2014(14); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished); |
| 453 | TSKVLEnSTK | 2015(unpublished); |
| 453 | VLEnSTKNSNDPA | 2009(64); |
| 453 | KTSKVLEnSTKNSNDPAVF | 2014(33); |
| 551 | QMTSnATQAFW | 2014(33); |
| 551 | YQMTSnATQAFW | 2014(33); |
| 551 | YQMTSnATQAFWTK | 2012(48); 2014(33); |
| 551 | GKPFYQMTSnATQAFWTK | 2014(33); |
| 551 | EGKPFYQMTSnATQAFWTK | 2012(48); 2014(13); 2014(33); 2015(unpublished);2015(unpublished);2007(unpublished);2007(unpublished);2007;2007; |
| 551 | EKEGKPFYQMTSnATQAFWTK | 2014(16); 2015(unpublished);2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MQPRWAQGAT | MWLGVLLTLL | LCSSLEGQEN | SFTINSVDMK | SLPDWTVQNG | KNLTLQCFAD | VSTTSHVKPQ | HQMLFYKDDV | LFYNISSMKS | TESYFIPEVR |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| IYDSGTYKCT | VIVNNKEKTT | AEYQLLVEGV | PSPRVTLDKK | EAIQGGIVRV | NCSVPEEKAP | IHFTIEKLEL | NEKMVKLKRE | KNSRDQNFVI | LEFPVEEQDR |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| VLSFRCQARI | ISGIHMQTSE | STKSELVTVT | ESFSTPKFHI | SPTGMIMEGA | QLHIKCTIQV | THLAQEFPEI | IIQKDKAIVA | HNRHGNKAVY | SVMAMVEHSG |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| NYTCKVESSR | ISKVSSIVVN | ITELFSKPEL | ESSFTHLDQG | ERLNLSCSIP | GAPPANFTIQ | KEDTIVSQTQ | DFTKIASKSD | SGTYICTAGI | DKVVKKSNTV |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| QIVVCEMLSQ | PRISYDAQFE | VIKGQTIEVR | CESISGTLPI | SYQLLKTSKV | LENSTKNSND | PAVFKDNPTE | DVEYQCVADN | CHSHAKMLSE | VLRVKVIAPV |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| DEVQISILSS | KVVESGEDIV | LQCAVNEGSG | PITYKFYREK | EGKPFYQMTS | NATQAFWTKQ | KASKEQEGEY | YCTAFNRANH | ASSVPRSKIL | TVRVILAPWK |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| KGLIAVVIIG | VIIALLIIAA | KCYFLRKAKA | KQMPVEMSRP | AVPLLNSNNE | KMSDPNMEAN | SHYGHNDDVR | NHAMKPINDN | KEPLNSDVQY | TEVQVSSAES |
| 701 | 711 | 721 | 731 | ||||||
| HKDLGKKDTE | TVYSEVRKAV | PDAVESRYSR | TEGSLDGT |
| ID | Publication |
|---|---|
| 3 | Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H: Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical proteomics 2015, 12:11. |
| 13 | Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 16 | Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |
| 45 | Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |
| 74 | Lewandrowski U, Zahedi RP, Moebius J, Walter U, Sickmann A: Enhanced N-glycosylation site analysis of Sialoglycopeptides by strong cation exchange prefractionation applied to platelet plasma membranes. Molecular & Cellular Proteomics 2007, 6:1933-1941. |