Detail

Contains

UniProtKB-P16473


Protein	Thyrotropin receptor
Gene	TSHR
Status	Reviewed
Source	Human; Lymphocytes; OVCAR-3 cell line (Ovarian cancer); Prostate tumor
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
77	TIPSHAFSNLPnISR	2015(1);
113	nLTYIDPDALK	2015(1);
113	VTHIEIRNTRnLTYIDPDAL	2015(6);
198	LYNNGFTSVQGYAFnGTK	2013(34); 2015(1); 2007(unpublished);2007(unpublished);
302	nESSMQSLR	2015(1);
302	GILESLMCnESSMQSLR	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
MRPADLLQLV	LLLDLPRDLG	GMGCSSPPCE	CHQEEDFRVT	CKDIQRIPSL	PPSTQTLKLI	ETHLRTIPSH	AFSNLPNISR	IYVSIDVTLQ	QLESHSFYNL
101	111	121	131	141	151	161	171	181	191
SKVTHIEIRN	TRNLTYIDPD	ALKELPLLKF	LGIFNTGLKM	FPDLTKVYST	DIFFILEITD	NPYMTSIPVN	AFQGLCNETL	TLKLYNNGFT	SVQGYAFNGT
201	211	221	231	241	251	261	271	281	291
KLDAVYLNKN	KYLTVIDKDA	FGGVYSGPSL	LDVSQTSVTA	LPSKGLEHLK	ELIARNTWTL	KKLPLSLSFL	HLTRADLSYP	SHCCAFKNQK	KIRGILESLM
301	311	321	331	341	351	361	371	381	391
CNESSMQSLR	QRKSVNALNS	PLHQEYEENL	GDSIVGYKEK	SKFQDTHNNA	HYYVFFEEQE	DEIIGFGQEL	KNPQEETLQA	FDSHYDYTIC	GDSEDMVCTP
401	411	421	431	441	451	461	471	481	491
KSDEFNPCED	IMGYKFLRIV	VWFVSLLALL	GNVFVLLILL	TSHYKLNVPR	FLMCNLAFAD	FCMGMYLLLI	ASVDLYTHSE	YYNHAIDWQT	GPGCNTAGFF
501	511	521	531	541	551	561	571	581	591
TVFASELSVY	TLTVITLERW	YAITFAMRLD	RKIRLRHACA	IMVGGWVCCF	LLALLPLVGI	SSYAKVSICL	PMDTETPLAL	AYIVFVLTLN	IVAFVIVCCC
601	611	621	631	641	651	661	671	681	691
YVKIYITVRN	PQYNPGDKDT	KIAKRMAVLI	FTDFICMAPI	SFYALSAILN	KPLITVSNSK	ILLVLFYPLN	SCANPFLYAI	FTKAFQRDVF	ILLSKFGICK
701	711	721	731	741	751	761
RQAQAYRGQR	VPPKNSTDIQ	VQKVTHDMRQ	GLHNMEDVYE	LIENSHLTPK	KQGQISEEYM	QTVL

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
6	Kim DS, Hahn Y: The acquisition of novel N-glycosylation sites in conserved proteins during human evolution. Bmc Bioinformatics 2015, 16.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.