| Protein | Sphingomyelin phosphodiesterase |
| Gene | SMPD1 |
| Status | Reviewed |
| Source | Hela cell line (cervical cancer); LNCap/PC3 cell lines (Prostate cancer); Liver; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Pancreatic islets; Prostate tumor; Spermatozoa; Urine |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 86 | nLTCPICK | 2015(1); |
| 86 | GWGnLTCPICK | 2012(48); 2014(33); |
| 86 | DVFGWGnITCPICK | 2013(43); |
| 86 | DVFGWGnLTCPICK | 2012(48); 2014(18); 2014(33); |
| 86 | LRDVFGWGnLTCPICK | 2014(18); |
| 335 | FLGPVPVYPAVGNHESTPVNSFPPPFIEGnHSSR | 2007(48); 2012(33); 2014(2); 2015(unpublished);2007(unpublished);2007; |
| 335 | KFIGPVPVYPAVGNHESTPVNSFPPPFIEGnHSSR | 2013(43); |
| 335 | KFLGPVPVYPAVGNHESTPVNSFPPPFIEGnHSSR | 2015(2); 2015(12); |
| 395 | ENFWLLInSTDPAGQLQWLVGELQAAEDR | 2015(2); |
| 503 | VYQIDGnYSGSSHVVLDHE | 2014(33); |
| 503 | VYQIDGnYSGSSHVVLDHETYILNLTQANIPGAIPHWQLLYR | 2015(2); |
| 520 | ILnLTQANIPGAIPHWQL | 2014(33); |
| 520 | TYILnLTQANIPGAIPHWQLLYR | 2014(33); |
| 520 | VYQIDGNYSGSSHVVLDHETYILnLTQANIPGAIPHWQLLYR | 2015(2); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MPRYGASLRQ | SCPRSGREQG | QDGTAGAPGL | LWMGLVLALA | LALALALSDS | RVLWAPAEAH | PLSPQGHPAR | LHRIVPRLRD | VFGWGNLTCP | ICKGLFTAIN |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| LGLKKEPNVA | RVGSVAIKLC | NLLKIAPPAV | CQSIVHLFED | DMVEVWRRSV | LSPSEACGLL | LGSTCGHWDI | FSSWNISLPT | VPKPPPKPPS | PPAPGAPVSR |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| ILFLTDLHWD | HDYLEGTDPD | CADPLCCRRG | SGLPPASRPG | AGYWGEYSKC | DLPLRTLESL | LSGLGPAGPF | DMVYWTGDIP | AHDVWHQTRQ | DQLRALTTVT |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| ALVRKFLGPV | PVYPAVGNHE | STPVNSFPPP | FIEGNHSSRW | LYEAMAKAWE | PWLPAEALRT | LRIGGFYALS | PYPGLRLISL | NMNFCSRENF | WLLINSTDPA |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| GQLQWLVGEL | QAAEDRGDKV | HIIGHIPPGH | CLKSWSWNYY | RIVARYENTL | AAQFFGHTHV | DEFEVFYDEE | TLSRPLAVAF | LAPSATTYIG | LNPGYRVYQI |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| DGNYSGSSHV | VLDHETYILN | LTQANIPGAI | PHWQLLYRAR | ETYGLPNTLP | TAWHNLVYRM | RGDMQLFQTF | WFLYHKGHPP | SEPCGTPCRL | ATLCAQLSAR |
| 601 | 611 | 621 | |||||||
| ADSPALCRHL | MPDGSLPEAQ | SLWPRPLFC |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 2 | Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763. |
| 12 | Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5. |
| 18 | Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 43 | Wang GG, Wu YB, Zhou T, Guo YS, Zheng B, Wang J, Bi Y, Liu FJ, Zhou ZM, Guo XJ, Sha JH: Mapping of the N-Linked Glycoproteome of Human Spermatozoa. Journal of Proteome Research 2013, 12:5750-5759. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |