Detail

UniProtKB-P20023


Protein	Complement receptor type 2
Gene	CR2
Status	Reviewed
Source	Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); Liver; Lymphocytes; Plasma; Prostate tumor; Serum; Serum (HCC); plasma
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
294	HIGNSLAnVSYGSIVTYTCDPDPEEGVNFILIGESTLR	2015(unpublished);
492	VRPDVnSSCGEGY	2014(33);
623	EAPYFYnDTVTFK	2013(38); 2014(16); 2014(22); 2014(33); 2015(8); 2015(10); 2007(unpublished);2007(unpublished);2007(unpublished);
823	THSAYSHNDIVYVDCNPGFIMnGSR	2013(45); 2015(unpublished);
861	TPNGnHTGGNIAR	2014(13); 2014(16); 2015(10); 2015(unpublished);2007(unpublished);2007;
911	EVnCSSPADMDGIQK	2013(45); 2014(13); 2014(16); 2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MGAAGLLGVF	LALVAPGVLG	ISCGSPPPIL	NGRISYYSTP	IAVGTVIRYS	CSGTFRLIGE	KSLLCITKDK	VDGTWDKPAP	KCEYFNKYSS	CPEPIVPGGY
101	111	121	131	141	151	161	171	181	191
KIRGSTPYRH	GDSVTFACKT	NFSMNGNKSV	WCQANNMWGP	TRLPTCVSVF	PLECPALPMI	HNGHHTSENV	GSIAPGLSVT	YSCESGYLLV	GEKIINCLSS
201	211	221	231	241	251	261	271	281	291
GKWSAVPPTC	EEARCKSLGR	FPNGKVKEPP	ILRVGVTANF	FCDEGYRLQG	PPSSRCVIAG	QGVAWTKMPV	CEEIFCPSPP	PILNGRHIGN	SLANVSYGSI
301	311	321	331	341	351	361	371	381	391
VTYTCDPDPE	EGVNFILIGE	STLRCTVDSQ	KTGTWSGPAP	RCELSTSAVQ	CPHPQILRGR	MVSGQKDRYT	YNDTVIFACM	FGFTLKGSKQ	IRCNAQGTWE
401	411	421	431	441	451	461	471	481	491
PSAPVCEKEC	QAPPNILNGQ	KEDRHMVRFD	PGTSIKYSCN	PGYVLVGEES	IQCTSEGVWT	PPVPQCKVAA	CEATGRQLLT	KPQHQFVRPD	VNSSCGEGYK
501	511	521	531	541	551	561	571	581	591
LSGSVYQECQ	GTIPWFMEIR	LCKEITCPPP	PVIYNGAHTG	SSLEDFPYGT	TVTYTCNPGP	ERGVEFSLIG	ESTIRCTSND	QERGTWSGPA	PLCKLSLLAV
601	611	621	631	641	651	661	671	681	691
QCSHVHIANG	YKISGKEAPY	FYNDTVTFKC	YSGFTLKGSS	QIRCKADNTW	DPEIPVCEKE	TCQHVRQSLQ	ELPAGSRVEL	VNTSCQDGYQ	LTGHAYQMCQ
701	711	721	731	741	751	761	771	781	791
DAENGIWFKK	IPLCKVIHCH	PPPVIVNGKH	TGMMAENFLY	GNEVSYECDQ	GFYLLGEKKL	QCRSDSKGHG	SWSGPSPQCL	RSPPVTRCPN	PEVKHGYKLN
801	811	821	831	841	851	861	871	881	891
KTHSAYSHND	IVYVDCNPGF	IMNGSRVIRC	HTDNTWVPGV	PTCIKKAFIG	CPPPPKTPNG	NHTGGNIARF	SPGMSILYSC	DQGYLLVGEA	LLLCTHEGTW
901	911	921	931	941	951	961	971	981	991
SQPAPHCKEV	NCSSPADMDG	IQKGLEPRKM	YQYGAVVTLE	CEDGYMLEGS	PQSQCQSDHQ	WNPPLAVCRS	RSLAPVLCGI	AAGLILLTFL	IVITLYVISK
1001	1011	1021	1031
HRARNYYTDT	SQKEAFHLEA	REVYSVDPYN	PAS

Reference

ID	Publication
8	Ma C, Zhang Q, Qu JY, Zhao XY, Li X, Liu YP, Wang PG: A precise approach in large scale core-fucosylated glycoprotein identification with low- and high-normalized collision energy. Journal of Proteomics 2015, 114:61-70.
10	Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978.
13	Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
38	Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640.
45	Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.