Detail

UniProtKB-P20701


Protein	Integrin alpha-L
Gene	ITGAL
Status	Reviewed
Source	Cerebrospinal fluid; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); Liver; Liver tumor (HCC); Lymphocytes; Ovarian tumor; Ovarian tumorJurkat T cell line; Ovarian tumorPBMC Macrophage cells; Prostate tumor
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
65	RVLQVGNGVIVGAPGEGnSTGSLY	2014(33);
65	VIQVGNGVIVGAPGEGnSTGSIYQCQSGTGHCIPVTIR	2014(16);
65	VLQVGNGVIVGAPGEGnSTGSLYQCQSGTGHCLPVTLR	2007(unpublished);2007(unpublished);
89	GSnYTSK	2015(unpublished);
670	IVAnITYTIQIDGHR	2014(16);
670	LVAnLTYTLQLDGHR	2014(33); 2015(unpublished);
670	LVAnLTYTLQLDGHRTRR	2007(unpublished);2007(unpublished);
862	SCnVSSPIFK	2014(33);
862	AISCnVSSPIFK	2014(16); 2014(32);
862	ALSCnVSSPIFK	2013(34); 2014(13); 2014(22); 2014(33); 2015(unpublished);2015(unpublished);2007;2007;
862	SCnVSSPIFKAGHSVAL	2014(33);
897	LHAnVTCNNE	2014(33);
1060	SISFnSSK	2014(33);
1060	SISFnSSKHF	2014(33);
1071	GSnASLAQVVMK	2014(33);
1071	HFHLYGSnASLAQVVMK	2014(33);

Sequence

1	11	21	31	41	51	61	71	81	91
MKDSCITVMA	MALLSGFFFF	APASSYNLDV	RGARSFSPPR	AGRHFGYRVL	QVGNGVIVGA	PGEGNSTGSL	YQCQSGTGHC	LPVTLRGSNY	TSKYLGMTLA
101	111	121	131	141	151	161	171	181	191
TDPTDGSILA	CDPGLSRTCD	QNTYLSGLCY	LFRQNLQGPM	LQGRPGFQEC	IKGNVDLVFL	FDGSMSLQPD	EFQKILDFMK	DVMKKLSNTS	YQFAAVQFST
201	211	221	231	241	251	261	271	281	291
SYKTEFDFSD	YVKRKDPDAL	LKHVKHMLLL	TNTFGAINYV	ATEVFREELG	ARPDATKVLI	IITDGEATDS	GNIDAAKDII	RYIIGIGKHF	QTKESQETLH
301	311	321	331	341	351	361	371	381	391
KFASKPASEF	VKILDTFEKL	KDLFTELQKK	IYVIEGTSKQ	DLTSFNMELS	SSGISADLSR	GHAVVGAVGA	KDWAGGFLDL	KADLQDDTFI	GNEPLTPEVR
401	411	421	431	441	451	461	471	481	491
AGYLGYTVTW	LPSRQKTSLL	ASGAPRYQHM	GRVLLFQEPQ	GGGHWSQVQT	IHGTQIGSYF	GGELCGVDVD	QDGETELLLI	GAPLFYGEQR	GGRVFIYQRR
501	511	521	531	541	551	561	571	581	591
QLGFEEVSEL	QGDPGYPLGR	FGEAITALTD	INGDGLVDVA	VGAPLEEQGA	VYIFNGRHGG	LSPQPSQRIE	GTQVLSGIQW	FGRSIHGVKD	LEGDGLADVA
601	611	621	631	641	651	661	671	681	691
VGAESQMIVL	SSRPVVDMVT	LMSFSPAEIP	VHEVECSYST	SNKMKEGVNI	TICFQIKSLI	PQFQGRLVAN	LTYTLQLDGH	RTRRRGLFPG	GRHELRRNIA
701	711	721	731	741	751	761	771	781	791
VTTSMSCTDF	SFHFPVCVQD	LISPINVSLN	FSLWEEEGTP	RDQRAQGKDI	PPILRPSLHS	ETWEIPFEKN	CGEDKKCEAN	LRVSFSPARS	RALRLTAFAS
801	811	821	831	841	851	861	871	881	891
LSVELSLSNL	EEDAYWVQLD	LHFPPGLSFR	KVEMLKPHSQ	IPVSCEELPE	ESRLLSRALS	CNVSSPIFKA	GHSVALQMMF	NTLVNSSWGD	SVELHANVTC
901	911	921	931	941	951	961	971	981	991
NNEDSDLLED	NSATTIIPIL	YPINILIQDQ	EDSTLYVSFT	PKGPKIHQVK	HMYQVRIQPS	IHDHNIPTLE	AVVGVPQPPS	EGPITHQWSV	QMEPPVPCHY
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
EDLERLPDAA	EPCLPGALFR	CPVVFRQEIL	VQVIGTLELV	GEIEASSMFS	LCSSLSISFN	SSKHFHLYGS	NASLAQVVMK	VDVVYEKQML	YLYVLSGIGG
1101	1111	1121	1131	1141	1151	1161
LLLLLLIFIV	LYKVGFFKRN	LKEKMEAGRG	VPNGIPAEDS	EQLASGQEAG	DPGCLKPLHE	KDSESGGGKD

Reference

ID	Publication
13	Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
32	Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.