Detail

Contains

UniProtKB-P22102


Protein	Trifunctional purine biosynthetic protein adenosine-3
Gene	GART
Status	Reviewed
Source	Breast cancer xenografts; OVCAR-3 cell line (Ovarian cancer); Prostate; Prostate tumor; Serum
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
331	nHTALTVVMASK	2015(1);
788	QInGSVLK	2007(unpublished);2007(unpublished);
794	nGSLTNHFSFEK	2014(14); 2015(1); 2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MAARVLIIGS	GGREHTLAWK	LAQSHHVKQV	LVAPGNAGTA	CSEKISNTAI	SISDHTALAQ	FCKEKKIEFV	VVGPEAPLAA	GIVGNLRSAG	VQCFGPTAEA
101	111	121	131	141	151	161	171	181	191
AQLESSKRFA	KEFMDRHGIP	TAQWKAFTKP	EEACSFILSA	DFPALVVKAS	GLAAGKGVIV	AKSKEEACKA	VQEIMQEKAF	GAAGETIVIE	ELLDGEEVSC
201	211	221	231	241	251	261	271	281	291
LCFTDGKTVA	PMPPAQDHKR	LLEGDGGPNT	GGMGAYCPAP	QVSNDLLLKI	KDTVLQRTVD	GMQQEGTPYT	GILYAGIMLT	KNGPKVLEFN	CRFGDPECQV
301	311	321	331	341	351	361	371	381	391
ILPLLKSDLY	EVIQSTLDGL	LCTSLPVWLE	NHTALTVVMA	SKGYPGDYTK	GVEITGFPEA	QALGLEVFHA	GTALKNGKVV	THGGRVLAVT	AIRENLISAL
401	411	421	431	441	451	461	471	481	491
EEAKKGLAAI	KFEGAIYRKD	VGFRAIAFLQ	QPRSLTYKES	GVDIAAGNML	VKKIQPLAKA	TSRSGCKVDL	GGFAGLFDLK	AAGFKDPLLA	SGTDGVGTKL
501	511	521	531	541	551	561	571	581	591
KIAQLCNKHD	TIGQDLVAMC	VNDILAQGAE	PLFFLDYFSC	GKLDLSVTEA	VVAGIAKACG	KAGCALLGGE	TAEMPDMYPP	GEYDLAGFAV	GAMERDQKLP
601	611	621	631	641	651	661	671	681	691
HLERITEGDV	VVGIASSGLH	SNGFSLVRKI	VAKSSLQYSS	PAPDGCGDQT	LGDLLLTPTR	IYSHSLLPVL	RSGHVKAFAH	ITGGGLLENI	PRVLPEKLGV
701	711	721	731	741	751	761	771	781	791
DLDAQTWRIP	RVFSWLQQEG	HLSEEEMART	FNCGVGAVLV	VSKEQTEQIL	RDIQQHKEEA	WVIGSVVARA	EGSPRVKVKN	LIESMQINGS	VLKNGSLTNH
801	811	821	831	841	851	861	871	881	891
FSFEKKKARV	AVLISGTGSN	LQALIDSTRE	PNSSAQIDIV	ISNKAAVAGL	DKAERAGIPT	RVINHKLYKN	RVEFDSAIDL	VLEEFSIDIV	CLAGFMRILS
901	911	921	931	941	951	961	971	981	991
GPFVQKWNGK	MLNIHPSLLP	SFKGSNAHEQ	ALETGVTVTG	CTVHFVAEDV	DAGQIILQEA	VPVKRGDTVA	TLSERVKLAE	HKIFPAALQL	VASGTVQLGE
1001
NGKICWVKEE

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.