Detail

UniProtKB-P22760


Protein	Arylacetamide deacetylase
Gene	AADAC
Status	Reviewed
Source	Liver; Liver tumor (HCC); OVCAR-3 cell line (Ovarian cancer); Pancreatic islets
Years	2009-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
78	nVTVTETK	2015(1);
78	EnVTVTETK	2014(19); 2014(33);
78	DEnVTVTETK	2014(33);
78	TSDEnVTVTETK	2014(33);
78	PPTSDEnVTVTETK	2014(33);
78	DEVPPTSDEnVTVTE	2014(33);
78	FDEVPPTSDEnVTVTE	2014(33);
78	SFDEVPPTSDEnVTVTE	2014(33);
78	DEVPPTSDEnVTVTETKF	2014(33);
78	FDEVPPTSDEnVTVTETK	2009(64);
78	KVVGSFDEVPPTSDEnVTVT	2014(33);
78	VVGSFDEVPPTSDEnVTVTE	2014(33);
78	KVVGSFDEVPPTSDEnVTVTE	2014(33);
78	KVVGSFDEVPPTSDEnVTVTET	2014(33);
78	VVGSFDEVPPTSDEnVTVTETK	2009(64); 2012(48); 2014(33);
78	KVVGSFDEVPPTSDEnVTVTETK	2014(33);
78	PPTSDEnVTVTETKFNNILVRVY	2014(33);
78	VVGSFDEVPPTSDEnVTVTETKF	2014(33);
78	KVVGSFDEVPPTSDEnVTVTETKF	2014(33);
78	KVVGSFDEVPPTSDEnVTVTETKFNNIL	2014(33);
78	VVGSFDEVPPTSDEnVTVTETKFNNILVR	2014(33);
78	KVVGSFDEVPPTSDEnVTVTETKFNNILVRVY	2014(33);
282	KFVnW	2014(33);
282	FVnWSSLL	2014(33);
282	FVnWSSLLPE	2014(33);
282	VnWSSLLPER	2014(33);
282	FVnWSSIIPER	2014(32); 2014(32);
282	FVnWSSLLPER	2014(19); 2014(33);
282	KFVnWSSLLPE	2014(33);
282	VnWSSLLPERF	2014(33);
282	FVnWSSLLPERF	2014(33);
282	KFVnWSSLLPER	2014(33);
282	KFVnWSSLLPERF	2014(33);
282	FVnWSSLLPERFIK	2014(33);
282	KFVnWSSLLPERFIK	2014(33);
282	KFVnWSSLLPERFIKGHVY	2014(33);
282	SRQHVPVESSHLFKFVnWSSLLPERF	2014(33);

Sequence

1	11	21	31	41	51	61	71	81	91
MGRKSLYLLI	VGILIAYYIY	TPLPDNVEEP	WRMMWINAHL	KTIQNLATFV	ELLGLHHFMD	SFKVVGSFDE	VPPTSDENVT	VTETKFNNIL	VRVYVPKRKS
101	111	121	131	141	151	161	171	181	191
EALRRGLFYI	HGGGWCVGSA	ALSGYDLLSR	WTADRLDAVV	VSTNYRLAPK	YHFPIQFEDV	YNALRWFLRK	KVLAKYGVNP	ERIGISGDSA	GGNLAAAVTQ
201	211	221	231	241	251	261	271	281	291
QLLDDPDVKI	KLKIQSLIYP	ALQPLDVDLP	SYQENSNFLF	LSKSLMVRFW	SEYFTTDRSL	EKAMLSRQHV	PVESSHLFKF	VNWSSLLPER	FIKGHVYNNP
301	311	321	331	341	351	361	371	381	391
NYGSSELAKK	YPGFLDVRAA	PLLADDNKLR	GLPLTYVITC	QYDLLRDDGL	MYVTRLRNTG	VQVTHNHVED	GFHGAFSFLG	LKISHRLINQ	YIEWLKENL

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
19	Huang G, Sun Z, Qin H, Zhao L, Xiong Z, Peng X, Ou J, Zou H: Preparation of hydrazine functionalized polymer brushes hybrid magnetic nanoparticles for highly specific enrichment of glycopeptides. Analyst 2014, 139:2199-2206.
32	Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.
64	Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661.