Detail

UniProtKB-P23467


Protein	Receptor-type tyrosine-protein phosphatase beta
Gene	PTPRB
Status	Reviewed
Source	Breast cancer xenografts; HCC cell lines (Liver); Liver; Ovarian tumor; Plasma; Prostate tumor; SKOV-3 cell line (Ovarian cancer); Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
75	IDnTTYGCNLQ	2007(unpublished);2007(unpublished);2007;
172	YTFFnLTAGSK	2014(33);
198	SFSVYTnGSTVPSPVK	2013(34); 2013(40); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);
321	WQRPPGNVDSYnITLSHK	2015(8);
421	nITVGKEETQY	2014(33);
652	TVPSSVSGVTVnNSGR	2015(unpublished);2007(unpublished);2007;
1163	MVIVTHSGELSnE	2014(33);

Sequence

1	11	21	31	41	51	61	71	81	91
MLSHGAGLAL	WITLSLLQTG	LAEPERCNFT	LAESKASSHS	VSIQWRILGS	PCNFSLIYSS	DTLGAALCPT	FRIDNTTYGC	NLQDLQAGTI	YNFRIISLDE
101	111	121	131	141	151	161	171	181	191
ERTVVLQTDP	LPPARFGVSK	EKTTSTSLHV	WWTPSSGKVT	SYEVQLFDEN	NQKIQGVQIQ	ESTSWNEYTF	FNLTAGSKYN	IAITAVSGGK	RSFSVYTNGS
201	211	221	231	241	251	261	271	281	291
TVPSPVKDIG	ISTKANSLLI	SWSHGSGNVE	RYRLMLMDKG	ILVHGGVVDK	HATSYAFHGL	TPGYLYNLTV	MTEAAGLQNY	RWKLVRTAPM	EVSNLKVTND
301	311	321	331	341	351	361	371	381	391
GSLTSLKVKW	QRPPGNVDSY	NITLSHKGTI	KESRVLAPWI	TETHFKELVP	GRLYQVTVSC	VSGELSAQKM	AVGRTFPDKV	ANLEANNNGR	MRSLVVSWSP
401	411	421	431	441	451	461	471	481	491
PAGDWEQYRI	LLFNDSVVLL	NITVGKEETQ	YVMDDTGLVP	GRQYEVEVIV	ESGNLKNSER	CQGRTVPLAV	LQLRVKHANE	TSLSIMWQTP	VAEWEKYIIS
501	511	521	531	541	551	561	571	581	591
LADRDLLLIH	KSLSKDAKEF	TFTDLVPGRK	YMATVTSISG	DLKNSSSVKG	RTVPAQVTDL	HVANQGMTSS	LFTNWTQAQG	DVEFYQVLLI	HENVVIKNES
601	611	621	631	641	651	661	671	681	691
ISSETSRYSF	HSLKSGSLYS	VVVTTVSGGI	SSRQVVVEGR	TVPSSVSGVT	VNNSGRNDYL	SVSWLLAPGD	VDNYEVTLSH	DGKVVQSLVI	AKSVRECSFS
701	711	721	731	741	751	761	771	781	791
SLTPGRLYTV	TITTRSGKYE	NHSFSQERTV	PDKVQGVSVS	NSARSDYLRV	SWVHATGDFD	HYEVTIKNKN	NFIQTKSIPK	SENECVFVQL	VPGRLYSVTV
801	811	821	831	841	851	861	871	881	891
TTKSGQYEAN	EQGNGRTIPE	PVKDLTLRNR	STEDLHVTWS	GANGDVDQYE	IQLLFNDMKV	FPPFHLVNTA	TEYRFTSLTP	GRQYKILVLT	ISGDVQQSAF
901	911	921	931	941	951	961	971	981	991
IEGFTVPSAV	KNIHISPNGA	TDSLTVNWTP	GGGDVDSYTV	SAFRHSQKVD	SQTIPKHVFE	HTFHRLEAGE	QYQIMIASVS	GSLKNQINVV	GRTVPASVQG
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
VIADNAYSSY	SLIVSWQKAA	GVAERYDILL	LTENGILLRN	TSEPATTKQH	KFEDLTPGKK	YKIQILTVSG	GLFSKEAQTE	GRTVPAAVTD	LRITENSTRH
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
LSFRWTASEG	ELSWYNIFLY	NPDGNLQERA	QVDPLVQSFS	FQNLLQGRMY	KMVIVTHSGE	LSNESFIFGR	TVPASVSHLR	GSNRNTTDSL	WFNWSPASGD
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
FDFYELILYN	PNGTKKENWK	DKDLTEWRFQ	GLVPGRKYVL	WVVTHSGDLS	NKVTAESRTA	PSPPSLMSFA	DIANTSLAIT	WKGPPDWTDY	NDFELQWLPR
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
DALTVFNPYN	NRKSEGRIVY	GLRPGRSYQF	NVKTVSGDSW	KTYSKPIFGS	VRTKPDKIQN	LHCRPQNSTA	IACSWIPPDS	DFDGYSIECR	KMDTQEVEFS
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
RKLEKEKSLL	NIMMLVPHKR	YLVSIKVQSA	GMTSEVVEDS	TITMIDRPPP	PPPHIRVNEK	DVLISKSSIN	FTVNCSWFSD	TNGAVKYFTV	VVREADGSDE
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
LKPEQQHPLP	SYLEYRHNAS	IRVYQTNYFA	SKCAENPNSN	SKSFNIKLGA	EMESLGGKCD	PTQQKFCDGP	LKPHTAYRIS	IRAFTQLFDE	DLKEFTKPLY
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
SDTFFSLPIT	TESEPLFGAI	EGVSAGLFLI	GMLVAVVALL	ICRQKVSHGR	ERPSARLSIR	RDRPLSVHLN	LGQKGNRKTS	CPIKINQFEG	HFMKLQADSN
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
YLLSKEYEEL	KDVGRNQSCD	IALLPENRGK	NRYNNILPYD	ATRVKLSNVD	DDPCSDYINA	SYIPGNNFRR	EYIVTQGPLP	GTKDDFWKMV	WEQNVHNIVM
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
VTQCVEKGRV	KCDHYWPADQ	DSLYYGDLIL	QMLSESVLPE	WTIREFKICG	EEQLDAHRLI	RHFHYTVWPD	HGVPETTQSL	IQFVRTVRDY	INRSPGAGPT
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
VVHCSAGVGR	TGTFIALDRI	LQQLDSKDSV	DIYGAVHDLR	LHRVHMVQTE	CQYVYLHQCV	RDVLRARKLR	SEQENPLFPI	YENVNPEYHR	DPVYSRH

Reference

ID	Publication
8	Ma C, Zhang Q, Qu JY, Zhao XY, Li X, Liu YP, Wang PG: A precise approach in large scale core-fucosylated glycoprotein identification with low- and high-normalized collision energy. Journal of Proteomics 2015, 114:61-70.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.