Detail

UniProtKB-P23468


Protein	Receptor-type tyrosine-protein phosphatase delta
Gene	PTPRD
Status	Reviewed
Source	Colorectal tumor; Jurkat T cell line; Liver; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Serum
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
254	nITCVAVGSPMPYVK	2015(1);
724	VEVEAVnSTSVK	2014(22);
724	KVEVEAVnSTSVK	2014(13); 2014(18); 2014(33); 2015(1);
1640	LTQIETGEnVTGMELEFK	2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MVHVARLLLL	LLTFFLRTDA	ETPPRFTRTP	VDQTGVSGGV	ASFICQATGD	PRPKIVWNKK	GKKVSNQRFE	VIEFDDGSGS	VLRIQPLRTP	RDEAIYECVA
101	111	121	131	141	151	161	171	181	191
SNNVGEISVS	TRLTVLREDQ	IPRGFPTIDM	GPQLKVVERT	RTATMLCAAS	GNPDPEITWF	KDFLPVDTSN	NNGRIKQLRS	ESIGGTPIRG	ALQIEQSEES
201	211	221	231	241	251	261	271	281	291
DQGKYECVAT	NSAGTRYSAP	ANLYVRELRE	VRRVPPRFSI	PPTNHEIMPG	GSVNITCVAV	GSPMPYVKWM	LGAEDLTPED	DMPIGRNVLE	LNDVRQSANY
301	311	321	331	341	351	361	371	381	391
TCVAMSTLGV	IEAIAQITVK	ALPKPPGTPV	VTESTATSIT	LTWDSGNPEP	VSYYIIQHKP	KNSEELYKEI	DGVATTRYSV	AGLSPYSDYE	FRVVAVNNIG
401	411	421	431	441	451	461	471	481	491
RGPPSEPVLT	QTSEQAPSSA	PRDVQARMLS	STTILVQWKE	PEEPNGQIQG	YRVYYTMDPT	QHVNNWMKHN	VADSQITTIG	NLVPQKTYSV	KVLAFTSIGD
501	511	521	531	541	551	561	571	581	591
GPLSSDIQVI	TQTGVPGQPL	NFKAEPESET	SILLSWTPPR	SDTIANYELV	YKDGEHGEEQ	RITIEPGTSY	RLQGLKPNSL	YYFRLAARSP	QGLGASTAEI
601	611	621	631	641	651	661	671	681	691
SARTMQSKPS	APPQDISCTS	PSSTSILVSW	QPPPVEKQNG	IITEYSIKYT	AVDGEDDKPH	EILGIPSDTT	KYLLEQLEKW	TEYRITVTAH	TDVGPGPESL
701	711	721	731	741	751	761	771	781	791
SVLIRTNEDV	PSGPPRKVEV	EAVNSTSVKV	SWRSPVPNKQ	HGQIRGYQVH	YVRMENGEPK	GQPMLKDVML	ADAQWEFDDT	TEHDMIISGL	QPETSYSLTV
801	811	821	831	841	851	861	871	881	891
TAYTTKGDGA	RSKPKLVSTT	GAVPGKPRLV	INHTQMNTAL	IQWHPPVDTF	GPLQGYRLKF	GRKDMEPLTT	LEFSEKEDHF	TATDIHKGAS	YVFRLSARNK
901	911	921	931	941	951	961	971	981	991
VGFGEEMVKE	ISIPEEVPTG	FPQNLHSEGT	TSTSVQLSWQ	PPVLAERNGI	ITKYTLLYRD	INIPLLPMEQ	LIVPADTTMT	LTGLKPDTTY	DVKVRAHTSK
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
GPGPYSPSVQ	FRTLPVDQVF	AKNFHVKAVM	KTSVLLSWEI	PENYNSAMPF	KILYDDGKMV	EEVDGRATQK	LIVNLKPEKS	YSFVLTNRGN	SAGGLQHRVT
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
AKTAPDVLRT	KPAFIGKTNL	DGMITVQLPE	VPANENIKGY	YIIIVPLKKS	RGKFIKPWES	PDEMELDELL	KEISRKRRSI	RYGREVELKP	YIAAHFDVLP
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
TEFTLGDDKH	YGGFTNKQLQ	SGQEYVFFVL	AVMEHAESKM	YATSPYSDPV	VSMDLDPQPI	TDEEEGLIWV	VGPVLAVVFI	ICIVIAILLY	KRKRAESDSR
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
KSSIPNNKEI	PSHHPTDPVE	LRRLNFQTPG	MASHPPIPIL	ELADHIERLK	ANDNLKFSQE	YESIDPGQQF	TWEHSNLEVN	KPKNRYANVI	AYDHSRVLLS
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
AIEGIPGSDY	VNANYIDGYR	KQNAYIATQG	SLPETFGDFW	RMIWEQRSAT	VVMMTKLEER	SRVKCDQYWP	SRGTETHGLV	QVTLLDTVEL	ATYCVRTFAL
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
YKNGSSEKRE	VRQFQFTAWP	DHGVPEHPTP	FLAFLRRVKT	CNPPDAGPMV	VHCSAGVGRT	GCFIVIDAML	ERIKHEKTVD	IYGHVTLMRA	QRNYMVQTED
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
QYIFIHDALL	EAVTCGNTEV	PARNLYAYIQ	KLTQIETGEN	VTGMELEFKR	LASSKAHTSR	FISANLPCNK	FKNRLVNIMP	YESTRVCLQP	IRGVEGSDYI
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
NASFIDGYRQ	QKAYIATQGP	LAETTEDFWR	MLWEHNSTIV	VMLTKLREMG	REKCHQYWPA	ERSARYQYFV	VDPMAEYNMP	QYILREFKVT	DARDGQSRTV
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
RQFQFTDWPE	QGVPKSGEGF	IDFIGQVHKT	KEQFGQDGPI	SVHCSAGVGR	TGVFITLSIV	LERMRYEGVV	DIFQTVKMLR	TQRPAMVQTE	DQYQFSYRAA
1901	1911
LEYLGSFDHY	AT

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
13	Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.