Detail


Protein	Receptor-type tyrosine-protein phosphatase zeta
Gene	PTPRZ1
Status	Reviewed
Source	Breast Cancer cell lines; Cerebrospinal fluid; Plasma; Prostate tumor; Serum; Urine
Years	2005-2015

Site	Identified Peptides	Year(Publication ID)
105	TVEInLTNDYR	2005( 81); 2015(unpublished);2015(unpublished);2007(unpublished);2007;2007;
105	GKTVEInITNDYR	2013(37);
134	FHWGKCnMSSDGS	2013(37);
223	QAALDPFILLNLLPnSTDK	2007(unpublished);2007(unpublished);2007(unpublished);
677	ESFLQTnYTEIR	2013(45); 2015(5); 2015(unpublished);2015(unpublished);2007;2007;
677	ESFIQTnYTEIRV	2013(37);
1050	SEIIYGnETELQIPSFNEMVYPSESTVMPNMYDNVNK	2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MRILKRFLAC	IQLLCVCRLD	WANGYYRQQR	KLVEEIGWSY	TGALNQKNWG	KKYPTCNSPK	QSPINIDEDL	TQVNVNLKKL	KFQGWDKTSL	ENTFIHNTGK
101	111	121	131	141	151	161	171	181	191
TVEINLTNDY	RVSGGVSEMV	FKASKITFHW	GKCNMSSDGS	EHSLEGQKFP	LEMQIYCFDA	DRFSSFEEAV	KGKGKLRALS	ILFEVGTEEN	LDFKAIIDGV
201	211	221	231	241	251	261	271	281	291
ESVSRFGKQA	ALDPFILLNL	LPNSTDKYYI	YNGSLTSPPC	TDTVDWIVFK	DTVSISESQL	AVFCEVLTMQ	QSGYVMLMDY	LQNNFREQQY	KFSRQVFSSY
301	311	321	331	341	351	361	371	381	391
TGKEEIHEAV	CSSEPENVQA	DPENYTSLLV	TWERPRVVYD	TMIEKFAVLY	QQLDGEDQTK	HEFLTDGYQD	LGAILNNLLP	NMSYVLQIVA	ICTNGLYGKY
401	411	421	431	441	451	461	471	481	491
SDQLIVDMPT	DNPELDLFPE	LIGTEEIIKE	EEEGKDIEEG	AIVNPGRDSA	TNQIRKKEPQ	ISTTTHYNRI	GTKYNEAKTN	RSPTRGSEFS	GKGDVPNTSL
501	511	521	531	541	551	561	571	581	591
NSTSQPVTKL	ATEKDISLTS	QTVTELPPHT	VEGTSASLND	GSKTVLRSPH	MNLSGTAESL	NTVSITEYEE	ESLLTSFKLD	TGAEDSSGSS	PATSAIPFIS
601	611	621	631	641	651	661	671	681	691
ENISQGYIFS	SENPETITYD	VLIPESARNA	SEDSTSSGSE	ESLKDPSMEG	NVWFPSSTDI	TAQPDVGSGR	ESFLQTNYTE	IRVDESEKTT	KSFSAGPVMS
701	711	721	731	741	751	761	771	781	791
QGPSVTDLEM	PHYSTFAYFP	TEVTPHAFTP	SSRQQDLVST	VNVVYSQTTQ	PVYNGETPLQ	PSYSSEVFPL	VTPLLLDNQI	LNTTPAASSS	DSALHATPVF
801	811	821	831	841	851	861	871	881	891
PSVDVSFESI	LSSYDGAPLL	PFSSASFSSE	LFRHLHTVSQ	ILPQVTSATE	SDKVPLHASL	PVAGGDLLLE	PSLAQYSDVL	STTHAASETL	EFGSESGVLY
901	911	921	931	941	951	961	971	981	991
KTLMFSQVEP	PSSDAMMHAR	SSGPEPSYAL	SDNEGSQHIF	TVSYSSAIPV	HDSVGVTYQG	SLFSGPSHIP	IPKSSLITPT	ASLLQPTHAL	SGDGEWSGAS
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
SDSEFLLPDT	DGLTALNISS	PVSVAEFTYT	TSVFGDDNKA	LSKSEIIYGN	ETELQIPSFN	EMVYPSESTV	MPNMYDNVNK	LNASLQETSV	SISSTKGMFP
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
GSLAHTTTKV	FDHEISQVPE	NNFSVQPTHT	VSQASGDTSL	KPVLSANSEP	ASSDPASSEM	LSPSTQLLFY	ETSASFSTEV	LLQPSFQASD	VDTLLKTVLP
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
AVPSDPILVE	TPKVDKISST	MLHLIVSNSA	SSENMLHSTS	VPVFDVSPTS	HMHSASLQGL	TISYASEKYE	PVLLKSESSH	QVVPSLYSND	ELFQTANLEI
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
NQAHPPKGRH	VFATPVLSID	EPLNTLINKL	IHSDEILTST	KSSVTGKVFA	GIPTVASDTF	VSTDHSVPIG	NGHVAITAVS	PHRDGSVTST	KLLFPSKATS
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
ELSHSAKSDA	GLVGGGEDGD	TDDDGDDDDD	DRGSDGLSIH	KCMSCSSYRE	SQEKVMNDSD	THENSLMDQN	NPISYSLSEN	SEEDNRVTSV	SSDSQTGMDR
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
SPGKSPSANG	LSQKHNDGKE	ENDIQTGSAL	LPLSPESKAW	AVLTSDEESG	SGQGTSDSLN	ENETSTDFSF	ADTNEKDADG	ILAAGDSEIT	PGFPQSPTSS
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
VTSENSEVFH	VSEAEASNSS	HESRIGLAEG	LESEKKAVIP	LVIVSALTFI	CLVVLVGILI	YWRKCFQTAH	FYLEDSTSPR	VISTPPTPIF	PISDDVGAIP
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
IKHFPKHVAD	LHASSGFTEE	FETLKEFYQE	VQSCTVDLGI	TADSSNHPDN	KHKNRYINIV	AYDHSRVKLA	QLAEKDGKLT	DYINANYVDG	YNRPKAYIAA
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
QGPLKSTAED	FWRMIWEHNV	EVIVMITNLV	EKGRRKCDQY	WPADGSEEYG	NFLVTQKSVQ	VLAYYTVRNF	TLRNTKIKKG	SQKGRPSGRV	VTQYHYTQWP
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
DMGVPEYSLP	VLTFVRKAAY	AKRHAVGPVV	VHCSAGVGRT	GTYIVLDSML	QQIQHEGTVN	IFGFLKHIRS	QRNYLVQTEE	QYVFIHDTLV	EAILSKETEV
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
LDSHIHAYVN	ALLIPGPAGK	TKLEKQFQLL	SQSNIQQSDY	SAALKQCNRE	KNRTSSIIPV	ERSRVGISSL	SGEGTDYINA	SYIMGYYQSN	EFIITQHPLL
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
HTIKDFWRMI	WDHNAQLVVM	IPDGQNMAED	EFVYWPNKDE	PINCESFKVT	LMAEEHKCLS	NEEKLIIQDF	ILEATQDDYV	LEVRHFQCPK	WPNPDSPISK
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
TFELISVIKE	EAANRDGPMI	VHDEHGGVTA	GTFCALTTLM	HQLEKENSVD	VYQVAKMINL	MRPGVFADIE	QYQFLYKVIL	SLVSTRQEEN	PSTSLDSNGA
2301	2311
ALPDGNIAES	LESLV

Reference

ID	Publication
5	Goyallon A, Cholet S, Chapelle M, Junot C, Fenaille F: Evaluation of a combined glycomics and glycoproteomics approach for studying the major glycoproteins present in biofluids: Application to cerebrospinal fluid. Rapid Communications in Mass Spectrometry 2015, 29:461-473.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
45	Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.

UniProtKB-P23471

Glycosites

Sequence

Reference