Detail

Contains

UniProtKB-P26012


Protein	Integrin beta-8
Gene	ITGB8
Status	Reviewed
Source	Hela cell line (cervical cancer); OVCAR-3 cell line (Ovarian cancer); Ovarian tumor
Years	2013-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
233	nITEFEK	2015(1);
402	nITAICPDGSR	2015(1);
402	VQVENQVQGIYFnITAICPDGSR	2015(unpublished);2015(1);
421	nVTSNDEVLF	2015(1);
421	nVTSNDEVLFNVTVTMK	2015(unpublished);2015(1);
431	NVTSNDEVLFnVTVTMK	2015(unpublished);2015(1);
456	NYAIIKPIGFnETAK	2013(34); 2015(unpublished);2015(1); 2015(12);
648	nLSQAILDQCK	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
MCGSALAFFT	AAFVCLQNDR	RGPASFLWAA	WVFSLVLGLG	QGEDNRCASS	NAASCARCLA	LGPECGWCVQ	EDFISGGSRS	ERCDIVSNLI	SKGCSVDSIE
101	111	121	131	141	151	161	171	181	191
YPSVHVIIPT	ENEINTQVTP	GEVSIQLRPG	AEANFMLKVH	PLKKYPVDLY	YLVDVSASMH	NNIEKLNSVG	NDLSRKMAFF	SRDFRLGFGS	YVDKTVSPYI
201	211	221	231	241	251	261	271	281	291
SIHPERIHNQ	CSDYNLDCMP	PHGYIHVLSL	TENITEFEKA	VHRQKISGNI	DTPEGGFDAM	LQAAVCESHI	GWRKEAKRLL	LVMTDQTSHL	ALDSKLAGIV
301	311	321	331	341	351	361	371	381	391
VPNDGNCHLK	NNVYVKSTTM	EHPSLGQLSE	KLIDNNINVI	FAVQGKQFHW	YKDLLPLLPG	TIAGEIESKA	ANLNNLVVEA	YQKLISEVKV	QVENQVQGIY
401	411	421	431	441	451	461	471	481	491
FNITAICPDG	SRKPGMEGCR	NVTSNDEVLF	NVTVTMKKCD	VTGGKNYAII	KPIGFNETAK	IHIHRNCSCQ	CEDNRGPKGK	CVDETFLDSK	CFQCDENKCH
501	511	521	531	541	551	561	571	581	591
FDEDQFSSES	CKSHKDQPVC	SGRGVCVCGK	CSCHKIKLGK	VYGKYCEKDD	FSCPYHHGNL	CAGHGECEAG	RCQCFSGWEG	DRCQCPSAAA	QHCVNSKGQV
601	611	621	631	641	651	661	671	681	691
CSGRGTCVCG	RCECTDPRSI	GRFCEHCPTC	YTACKENWNC	MQCLHPHNLS	QAILDQCKTS	CALMEQQHYV	DQTSECFSSP	SYLRIFFIIF	IVTFLIGLLK
701	711	721	731	741	751	761
VLIIRQVILQ	WNSNKIKSSS	DYRVSASKKD	KLILQSVCTR	AVTYRREKPE	EIKMDISKLN	AHETFRCNF

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
34	Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615.