Contains      

UniProtKB-P28845

Protein Corticosteroid 11-beta-dehydrogenase isozyme 1
Gene HSD11B1
Status Reviewed
Source Liver; Liver tumor (HCC); Ovarian tumor; Prostate; Prostate tumor
Years 2009-2015

Glycosites

Site Identified Peptides Year(Publication ID)
123 ILNHITnT 2014(33);
123 NHITnTSL 2009(64); 2014(33);
123 HITnTSLNL 2014(33);
123 ITnTSLNLF 2014(33);
123 NHITnTSLN 2014(33);
123 HITnTSLNLF 2014(33);
123 ILNHITnTSL 2009(64); 2014(33);
123 LNHITnTSLN 2014(33);
123 NHITnTSLNL 2009(64); 2014(33);
123 ILNHITnTSLN 2014(33);
123 LNHITnTSLNL 2014(33);
123 NHITnTSLNLF 2014(33);
123 HITnTSLNLFHD 2014(33);
123 ILNHITnTSLNL 2009(64); 2014(33);
123 ITnTSLNLFHDD 2014(33);
123 LNHITnTSLNLF 2014(33);
123 MLILNHITnTSL 2014(33);
123 HITnTSLNLFHDD 2014(33);
123 ILNHITnTSLNLF 2014(33);
123 NHITnTSLNLFHD 2014(33);
123 LILNHITnTSLNLF 2014(33);
123 NHITnTSLNLFHDD 2014(33);
123 MLILNHITnTSLNLF 2014(33);
123 LMGGLDMLILNHITnT 2014(14); 2014(33);
123 NHITnTSLNLFHDDIH 2014(33);
123 ITnTSLNLFHDDIHHVR 2014(33);
123 MGGLDMLILNHITnTSL 2014(33);
123 NHITnTSLNLFHDDIHH 2014(33);
123 HITnTSLNLFHDDIHHVR 2014(33);
123 LMGGLDMLILNHITnTSL 2014(33);
123 MGGLDMLILNHITnTSLN 2014(33);
123 LMGGLDMLILNHITnTSLN 2014(33);
123 NHITnTSLNLFHDDIHHVR 2014(33);
123 LMGGLDMLILNHITnTSLNL 2014(33);
123 ILNHITnTSLNLFHDDIHHVR 2014(33);
123 LMGGLDMLILNHITnTSLNLF 2014(33);
123 LILNHITnTSLNLFHDDIHHVR 2014(33);
123 MLILNHITnTSLNLFHDDIHHVR 2014(33);
123 GLDMLILNHITnTSLNLFHDDIHHVR 2014(33);
123 LMGGLDMLILNHITnTSLNLFHDDIH 2014(33);
123 NHITnTSLNLFHDDIHHVRKSMEVNFL 2014(33);
123 VAQAGKLMGGLDMLILNHITnTSLNLF 2014(33);
123 IMGGIDMIIINHITnTSINIFHDDIHHVR 2014(32); 2014(32);
123 LMGGLDMLILNHITnTSLNLFHDDIHHVR 2009(64); 2014(33); 2015(unpublished);
123 LMGGLDMLILNHITnTSLNLFHDDIHHVRK 2014(33);
162 KQSnGSIVVV 2014(33);
162 QSnGSIVVVS 2014(33);
162 QSnGSIVVVSS 2014(33);
162 QSnGSIVVVSSL 2014(33);
162 KQSnGSIVVVSSL 2014(33);
162 LKQSnGSIVVVSSL 2014(33);
162 SnGSIVVVSSLAGK 2014(33);
162 MLKQSnGSIVVVSSL 2014(33);
162 QSnGSIVVVSSLAGK 2009(64); 2014(14); 2014(33); 2015(unpublished);2015(unpublished);
162 LKQSnGSIVVVSSLAGK 2014(33);
162 ALPMLKQSnGSIVVVSSL 2014(33);
162 TVAALPMLKQSnGSIVVV 2014(33);
162 AALPMLKQSnGSIVVVSSL 2014(33);
162 TVAALPMLKQSnGSIVVVSSL 2014(33);
162 TVAALPMLKQSnGSIVVVSSLAGK 2014(33);
162 VVLTVAALPMLKQSnGSIVVVSSL 2014(33);
162 LKQSnGSIVVVSSLAGKVAYPMVAAY 2014(33);
162 TVAALPMLKQSnGSIVVVSSLAGKVAYPMVAAY 2014(33);
162 KSMEVNFLSYVVLTVAALPMLKQSnGSIVVVSSLAGK 2014(33);
207 SVSRVnV 2014(33);
207 VnVSITL 2014(33);
207 RVnVSITL 2014(33);
207 SVSRVnVS 2014(33);
207 SVSRVnVSIT 2014(33);
207 VnVSITLCVL 2014(33);
207 SVSRVnVSITL 2014(33);
207 VnVSITLCVLGLIDTETAMK 2014(33);

Sequence

1112131415161718191
MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAE
101111121131141151161171181191
QFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKE
201211221231241251261271281291
YSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK

Reference

ID Publication
14Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
32Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
64Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661.