Detail

UniProtKB-P35916


Protein	Vascular endothelial growth factor receptor 3
Gene	FLT4
Status	Reviewed
Source	Liver; Plasma; Prostate; Prostate tumor; Serum; Urine
Years	2005-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
104	VLLLHEVHAnDTGSYVCYYK	2007(unpublished);2015(unpublished);2007(unpublished);2007;2007;
166	GLnVTL	2014(33);
299	TIHnVSQHDLGSY	2014(33);
299	SQQTHTELSSILTIHnVSQHDLGSYVCK	2015(10);
527	LVIQNAnVSAMYK	2005( 81); 2007(42); 2013(13); 2014(14); 2014(33); 2014(4); 2015(8); 2015(unpublished);2015(unpublished);2007(unpublished);2007;2007;
594	LnLSTLHDAHGNPLLLDCK	2014(33); 2015(unpublished);2015(8); 2015(10);

Sequence

1	11	21	31	41	51	61	71	81	91
MQRGAALCLR	LWLCLGLLDG	LVSGYSMTPP	TLNITEESHV	IDTGDSLSIS	CRGQHPLEWA	WPGAQEAPAT	GDKDSEDTGV	VRDCEGTDAR	PYCKVLLLHE
101	111	121	131	141	151	161	171	181	191
VHANDTGSYV	CYYKYIKARI	EGTTAASSYV	FVRDFEQPFI	NKPDTLLVNR	KDAMWVPCLV	SIPGLNVTLR	SQSSVLWPDG	QEVVWDDRRG	MLVSTPLLHD
201	211	221	231	241	251	261	271	281	291
ALYLQCETTW	GDQDFLSNPF	LVHITGNELY	DIQLLPRKSL	ELLVGEKLVL	NCTVWAEFNS	GVTFDWDYPG	KQAERGKWVP	ERRSQQTHTE	LSSILTIHNV
301	311	321	331	341	351	361	371	381	391
SQHDLGSYVC	KANNGIQRFR	ESTEVIVHEN	PFISVEWLKG	PILEATAGDE	LVKLPVKLAA	YPPPEFQWYK	DGKALSGRHS	PHALVLKEVT	EASTGTYTLA
401	411	421	431	441	451	461	471	481	491
LWNSAAGLRR	NISLELVVNV	PPQIHEKEAS	SPSIYSRHSR	QALTCTAYGV	PLPLSIQWHW	RPWTPCKMFA	QRSLRRRQQQ	DLMPQCRDWR	AVTTQDAVNP
501	511	521	531	541	551	561	571	581	591
IESLDTWTEF	VEGKNKTVSK	LVIQNANVSA	MYKCVVSNKV	GQDERLIYFY	VTTIPDGFTI	ESKPSEELLE	GQPVLLSCQA	DSYKYEHLRW	YRLNLSTLHD
601	611	621	631	641	651	661	671	681	691
AHGNPLLLDC	KNVHLFATPL	AASLEEVAPG	ARHATLSLSI	PRVAPEHEGH	YVCEVQDRRS	HDKHCHKKYL	SVQALEAPRL	TQNLTDLLVN	VSDSLEMQCL
701	711	721	731	741	751	761	771	781	791
VAGAHAPSIV	WYKDERLLEE	KSGVDLADSN	QKLSIQRVRE	EDAGRYLCSV	CNAKGCVNSS	ASVAVEGSED	KGSMEIVILV	GTGVIAVFFW	VLLLLIFCNM
801	811	821	831	841	851	861	871	881	891
RRPAHADIKT	GYLSIIMDPG	EVPLEEQCEY	LSYDASQWEF	PRERLHLGRV	LGYGAFGKVV	EASAFGIHKG	SSCDTVAVKM	LKEGATASEH	RALMSELKIL
901	911	921	931	941	951	961	971	981	991
IHIGNHLNVV	NLLGACTKPQ	GPLMVIVEFC	KYGNLSNFLR	AKRDAFSPCA	EKSPEQRGRF	RAMVELARLD	RRRPGSSDRV	LFARFSKTEG	GARRASPDQE
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
AEDLWLSPLT	MEDLVCYSFQ	VARGMEFLAS	RKCIHRDLAA	RNILLSESDV	VKICDFGLAR	DIYKDPDYVR	KGSARLPLKW	MAPESIFDKV	YTTQSDVWSF
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
GVLLWEIFSL	GASPYPGVQI	NEEFCQRLRD	GTRMRAPELA	TPAIRRIMLN	CWSGDPKARP	AFSELVEILG	DLLQGRGLQE	EEEVCMAPRS	SQSSEEGSFS
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
QVSTMALHIA	QADAEDSPPS	LQRHSLAARY	YNWVSFPGCL	ARGAETRGSS	RMKTFEEFPM	TPTTYKGSVD	NQTDSGMVLA	SEEFEQIESR	HRQESGFSCK
1301	1311	1321	1331	1341	1351	1361
GPGQNVAVTR	AHPDSQGRRR	RPERGARGGQ	VFYNSEYGEL	SEPSEEDHCS	PSARVTFFTD	NSY

Reference

ID	Publication
4	Cheow ESH, Sim KH, de Kleijn D, Lee CN, Sorokin V, Sze SK: Simultaneous Enrichment of Plasma Soluble and Extracellular Vesicular Glycoproteins Using Prolonged Ultracentrifugation-Electrostatic Repulsion-hydrophilic Interaction Chromatography (PUC-ERLIC) Approach. Molecular & Cellular Proteomics 2015, 14:1657-1671.
8	Ma C, Zhang Q, Qu JY, Zhao XY, Li X, Liu YP, Wang PG: A precise approach in large scale core-fucosylated glycoprotein identification with low- and high-normalized collision energy. Journal of Proteomics 2015, 114:61-70.
10	Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978.
13	Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
42	Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450.