Detail

UniProtKB-P40763


Protein	Signal transducer and activator of transcription 3
Gene	STAT3
Status	Reviewed
Source	Breast cancer xenografts; OVCAR-3 cell line (Ovarian cancer); Serum
Years	2015-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
192	SQGDMQDLNGNnQSVTR	2015(unpublished);
401	nGSLSAEFK	2015(1);
401	VMNMEESNnGSLSAEFK	2015(10);

Sequence

1	11	21	31	41	51	61	71	81	91
MAQWNQLQQL	DTRYLEQLHQ	LYSDSFPMEL	RQFLAPWIES	QDWAYAASKE	SHATLVFHNL	LGEIDQQYSR	FLQESNVLYQ	HNLRRIKQFL	QSRYLEKPME
101	111	121	131	141	151	161	171	181	191
IARIVARCLW	EESRLLQTAA	TAAQQGGQAN	HPTAAVVTEK	QQMLEQHLQD	VRKRVQDLEQ	KMKVVENLQD	DFDFNYKTLK	SQGDMQDLNG	NNQSVTRQKM
201	211	221	231	241	251	261	271	281	291
QQLEQMLTAL	DQMRRSIVSE	LAGLLSAMEY	VQKTLTDEEL	ADWKRRQQIA	CIGGPPNICL	DRLENWITSL	AESQLQTRQQ	IKKLEELQQK	VSYKGDPIVQ
301	311	321	331	341	351	361	371	381	391
HRPMLEERIV	ELFRNLMKSA	FVVERQPCMP	MHPDRPLVIK	TGVQFTTKVR	LLVKFPELNY	QLKIKVCIDK	DSGDVAALRG	SRKFNILGTN	TKVMNMEESN
401	411	421	431	441	451	461	471	481	491
NGSLSAEFKH	LTLREQRCGN	GGRANCDASL	IVTEELHLIT	FETEVYHQGL	KIDLETHSLP	VVVISNICQM	PNAWASILWY	NMLTNNPKNV	NFFTKPPIGT
501	511	521	531	541	551	561	571	581	591
WDQVAEVLSW	QFSSTTKRGL	SIEQLTTLAE	KLLGPGVNYS	GCQITWAKFC	KENMAGKGFS	FWVWLDNIID	LVKKYILALW	NEGYIMGFIS	KERERAILST
601	611	621	631	641	651	661	671	681	691
KPPGTFLLRF	SESSKEGGVT	FTWVEKDISG	KTQIQSVEPY	TKQQLNNMSF	AEIIMGYKIM	DATNILVSPL	VYLYPDIPKE	EAFGKYCRPE	SQEHPEADPG
701	711	721	731	741	751	761
SAAPYLKTKF	ICVTPTTCSN	TIDLPMSPRT	LDSLMQFGNN	GEGAEPSAGG	QFESLTFDME	LTSECATSPM

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
10	Tan ZJ, Yin HD, Nie S, Lin ZX, Zhu JH, Ruffin MT, Anderson MA, Simone DM, Lubman DM: Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry. Journal of Proteome Research 2015, 14:1968-1978.