Contains      

UniProtKB-P41217

Protein OX-2 membrane glycoprotein
Gene CD200
Status Reviewed
Source DLBCL cell lines (Diffuse large B-cell lymphoma); Liver; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Pancreatic islets; Prostate tumor; Urine
Years 2007-2015

Glycosites

Site Identified Peptides Year(Publication ID)
157 FSEDHLnIT 2007(unpublished);
157 DHLnITCSATAR 2012(48);
157 FSEDHLnITCSATA 2012(48);
157 FSEDHInITCSATAR 2014(16);
157 FSEDHLnITCSATAR 2007(unpublished);2012(48); 2014(33); 2015(unpublished);
181 nSTVTLSHPNGTTSVTSILHIK 2015(1);
181 SGIEnSTVTLSHPNGTTSVTSILHIK 2015(unpublished);2015(1);
181 SGIEnSTVTISHPNGTTSVTSIIHIKDPK 2014(16);
181 SGIEnSTVTLSHPNGTTSVTSILHIKDPK 2015(1);
190 SHPnGTTSVTSIL 2014(33);
190 nGTTSVTSILHIKDPK 2015(1);
190 NSTVTLSHPnGTTSVTSILHIK 2015(1);
190 SGIENSTVTLSHPnGTTSVTSILHIK 2015(unpublished);2015(1);
190 SGIENSTVTISHPnGTTSVTSIIHIKDPK 2014(16);
190 SGIENSTVTLSHPnGTTSVTSILHIKDPK 2015(1);

Sequence

1112131415161718191
MERLVIRMPFSHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLG
101111121131141151161171181191
LQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILH
201211221231241251261271
IKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGELSQGVQKMT

Reference

ID Publication
1Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
16Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
48Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.