Detail

UniProtKB-P42704


Protein	Leucine-rich PPR motif-containing protein, mitochondrial
Gene	LRPPRC
Status	Reviewed
Source	Breast cancer xenografts; LNCap/PC3 cell lines (Prostate cancer); Liver; OVCAR-3 cell line (Ovarian cancer)
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
823	QLHEAIVTLGLAEPSTnISFPLVTVHLEK	2015(2);
1024	nSSSASTTEPDFQK	2015(1);
1024	HSLnSSSASTTEPDFQK	2015(unpublished);
1024	KHSLnSSSASTTEPDFQK	2014(33);
1024	DVPELWYEDEKHSLnSSSASTTEPDFQK	2014(33);
1024	EGNQEVPFDVPELWYEDEKHSLnSSSASTTEPDFQK	2014(33);

Sequence

1	11	21	31	41	51	61	71	81	91
MAALLRSARW	LLRAGAAPRL	PLSLRLLPGG	PGRLHAASYL	PAARAGPVAG	GLLSPARLYA	IAAKEKDIQE	ESTFSSRKIS	NQFDWALMRL	DLSVRRTGRI
101	111	121	131	141	151	161	171	181	191
PKKLLQKVFN	DTCRSGGLGG	SHALLLLRSC	GSLLPELKLE	ERTEFAHRIW	DTLQKLGAVY	DVSHYNALLK	VYLQNEYKFS	PTDFLAKMEE	ANIQPNRVTY
201	211	221	231	241	251	261	271	281	291
QRLIASYCNV	GDIEGASKIL	GFMKTKDLPV	TEAVFSALVT	GHARAGDMEN	AENILTVMRD	AGIEPGPDTY	LALLNAYAEK	GDIDHVKQTL	EKVEKSELHL
301	311	321	331	341	351	361	371	381	391
MDRDLLQIIF	SFSKAGYPQY	VSEILEKVTC	ERRYIPDAMN	LILLLVTEKL	EDVALQILLA	CPVSKEDGPS	VFGSFFLQHC	VTMNTPVEKL	TDYCKKLKEV
401	411	421	431	441	451	461	471	481	491
QMHSFPLQFT	LHCALLANKT	DLAKALMKAV	KEEGFPIRPH	YFWPLLVGRR	KEKNVQGIIE	ILKGMQELGV	HPDQETYTDY	VIPCFDSVNS	ARAILQENGC
501	511	521	531	541	551	561	571	581	591
LSDSDMFSQA	GLRSEAANGN	LDFVLSFLKS	NTLPISLQSI	RSSLLLGFRR	SMNINLWSEI	TELLYKDGRY	CQEPRGPTEA	VGYFLYNLID	SMSDSEVQAK
601	611	621	631	641	651	661	671	681	691
EEHLRQYFHQ	LEKMNVKIPE	NIYRGIRNLL	ESYHVPELIK	DAHLLVESKN	LDFQKTVQLT	SSELESTLET	LKAENQPIRD	VLKQLILVLC	SEENMQKALE
701	711	721	731	741	751	761	771	781	791
LKAKYESDMV	TGGYAALINL	CCRHDKVEDA	LNLKEEFDRL	DSSAVLDTGK	YVGLVRVLAK	HGKLQDAINI	LKEMKEKDVL	IKDTTALSFF	HMLNGAALRG
801	811	821	831	841	851	861	871	881	891
EIETVKQLHE	AIVTLGLAEP	STNISFPLVT	VHLEKGDLST	ALEVAIDCYE	KYKVLPRIHD	VLCKLVEKGE	TDLIQKAMDF	VSQEQGEMVM	LYDLFFAFLQ
901	911	921	931	941	951	961	971	981	991
TGNYKEAKKI	IETPGIRARS	ARLQWFCDRC	VANNQVETLE	KLVELTQKLF	ECDRDQMYYN	LLKLYKINGD	WQRADAVWNK	IQEENVIPRE	KTLRLLAEIL
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
REGNQEVPFD	VPELWYEDEK	HSLNSSSAST	TEPDFQKDIL	IACRLNQKKG	AYDIFLNAKE	QNIVFNAETY	SNLIKLLMSE	DYFTQAMEVK	AFAETHIKGF
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
TLNDAANSRL	IITQVRRDYL	KEAVTTLKTV	LDQQQTPSRL	AVTRVIQALA	MKGDVENIEV	VQKMLNGLED	SIGLSKMVFI	NNIALAQIKN	NNIDAAIENI
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
ENMLTSENKV	IEPQYFGLAY	LFRKVIEEQL	EPAVEKISIM	AERLANQFAI	YKPVTDFFLQ	LVDAGKVDDA	RALLQRCGAI	AEQTPILLLF	LLRNSRKQGK
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
ASTVKSVLEL	IPELNEKEEA	YNSLMKSYVS	EKDVTSAKAL	YEHLTAKNTK	LDDLFLKRYA	SLLKYAGEPV	PFIEPPESFE	FYAQQLRKLR	ENSS

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
2	Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.