| Protein | Thrombospondin-3 |
| Gene | THBS3 |
| Status | Reviewed |
| Source | Breast Cancer cell lines; Breast cancer xenografts; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); HCC cell lines (Liver); Liver; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Serum |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 407 | nQSQGCLPAR | 2015(1); |
| 407 | RIGFIGnQSQGCI | 2013(37); |
| 407 | IGFIGnQSQGCIPAR | 2014(16); |
| 407 | LGFLGnQSQGCLPAR | 2013(34); 2013(34); 2013(40); 2014(18); 2014(22); 2014(33); 2015(1); 2015(unpublished);2015(unpublished);2007;2007; |
| 644 | DNCPQLPnSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCR | 2015(unpublished); |
| 937 | CnDTVPEDFEPFR | 2013(40); 2015(unpublished); |
| 937 | NIQYRCnDTVPED | 2013(37); |
| 937 | RCnDTVPEDFEPF | 2014(33); |
| 937 | CnDTVPEDFEPFRR | 2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| METQELRGAL | ALLLLCFFTS | ASQDLQVIDL | LTVGESRQMV | AVAEKIRTAL | LTAGDIYLLS | TFRLPPKQGG | VLFGLYSRQD | NTRWLEASVV | GKINKVLVRY |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| QREDGKVHAV | NLQQAGLADG | RTHTVLLRLR | GPSRPSPALH | LYVDCKLGDQ | HAGLPALAPI | PPAEVDGLEI | RTGQKAYLRM | QGFVESMKII | LGGSMARVGA |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| LSECPFQGDE | SIHSAVTNAL | HSILGEQTKA | LVTQLTLFNQ | ILVELRDDIR | DQVKEMSLIR | NTIMECQVCG | FHEQRSHCSP | NPCFRGVDCM | EVYEYPGYRC |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| GPCPPGLQGN | GTHCSDINEC | AHADPCFPGS | SCINTMPGFH | CEACPRGYKG | TQVSGVGIDY | ARASKQVCND | IDECNDGNNG | GCDPNSICTN | TVGSFKCGPC |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| RLGFLGNQSQ | GCLPARTCHS | PAHSPCHIHA | HCLFERNGAV | SCQCNVGWAG | NGNVCGTDTD | IDGYPDQALP | CMDNNKHCKQ | DNCLLTPNSG | QEDADNDGVG |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| DQCDDDADGD | GIKNVEDNCR | LFPNKDQQNS | DTDSFGDACD | NCPNVPNNDQ | KDTDGNGEGD | ACDNDVDGDG | IPNGLDNCPK | VPNPLQTDRD | EDGVGDACDS |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| CPEMSNPTQT | DADSDLVGDV | CDTNEDSDGD | GHQDTKDNCP | QLPNSSQLDS | DNDGLGDECD | GDDDNDGIPD | YVPPGPDNCR | LVPNPNQKDS | DGNGVGDVCE |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| DDFDNDAVVD | PLDVCPESAE | VTLTDFRAYQ | TVVLDPEGDA | QIDPNWVVLN | QGMEIVQTMN | SDPGLAVGYT | AFNGVDFEGT | FHVNTVTDDD | YAGFLFSYQD |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| SGRFYVVMWK | QTEQTYWQAT | PFRAVAQPGL | QLKAVTSVSG | PGEHLRNALW | HTGHTPDQVR | LLWTDPRNVG | WRDKTSYRWQ | LLHRPQVGYI | RVKLYEGPQL |
| 901 | 911 | 921 | 931 | 941 | 951 | ||||
| VADSGVIIDT | SMRGGRLGVF | CFSQENIIWS | NLQYRCNDTV | PEDFEPFRRQ | LLQGRV |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 16 | Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251. |
| 18 | Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 34 | Sun S, Zhang B, Aiyetan P, Zhou J-Y, Shah P, Yang W, Levine DA, Zhang Z, Chan DW, Zhang H: Analysis of N-glycoproteins using Genomic N-glycosite Prediction. Journal of Proteome Research 2013, 12:5609-5615. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |