Detail

Contains

UniProtKB-P49915


Protein	GMP synthase [glutamine-hydrolyzing]
Gene	GMPS
Status	Reviewed
Source	Breast cancer xenografts; OVCAR-3 cell line (Ovarian cancer); Prostate
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
130	nISVDNTCSLFR	2015(1);
305	nGTTTLPISDEDR	2015(1);
305	nGTTTLPISDEDRTPR	2015(1);
305	VINAAHSFYnGTTTLPISDEDR	2015(unpublished);
328	nMTTSPEEK	2015(1);
328	TLnMTTSPEEK	2014(14);
393	nDTELIR	2015(1);
393	THHnDTELIR	2014(14);

Sequence

1	11	21	31	41	51	61	71	81	91
MALCNGDSKL	ENAGGDLKDG	HHHYEGAVVI	LDAGAQYGKV	IDRRVRELFV	QSEIFPLETP	AFAIKEQGFR	AIIISGGPNS	VYAEDAPWFD	PAIFTIGKPV
101	111	121	131	141	151	161	171	181	191
LGICYGMQMM	NKVFGGTVHK	KSVREDGVFN	ISVDNTCSLF	RGLQKEEVVL	LTHGDSVDKV	ADGFKVVARS	GNIVAGIANE	SKKLYGAQFH	PEVGLTENGK
201	211	221	231	241	251	261	271	281	291
VILKNFLYDI	AGCSGTFTVQ	NRELECIREI	KERVGTSKVL	VLLSGGVDST	VCTALLNRAL	NQEQVIAVHI	DNGFMRKRES	QSVEEALKKL	GIQVKVINAA
301	311	321	331	341	351	361	371	381	391
HSFYNGTTTL	PISDEDRTPR	KRISKTLNMT	TSPEEKRKII	GDTFVKIANE	VIGEMNLKPE	EVFLAQGTLR	PDLIESASLV	ASGKAELIKT	HHNDTELIRK
401	411	421	431	441	451	461	471	481	491
LREEGKVIEP	LKDFHKDEVR	ILGRELGLPE	ELVSRHPFPG	PGLAIRVICA	EEPYICKDFP	ETNNILKIVA	DFSASVKKPH	TLLQRVKACT	TEEDQEKLMQ
501	511	521	531	541	551	561	571	581	591
ITSLHSLNAF	LLPIKTVGVQ	GDCRSYSYVC	GISSKDEPDW	ESLIFLARLI	PRMCHNVNRV	VYIFGPPVKE	PPTDVTPTFL	TTGVLSTLRQ	ADFEAHNILR
601	611	621	631	641	651	661	671	681	691
ESGYAGKISQ	MPVILTPLHF	DRDPLQKQPS	CQRSVVIRTF	ITSDFMTGIP	ATPGNEIPVE	VVLKMVTEIK	KIPGISRIMY	DLTSKPPGTT	EWE

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.