Detail

Contains

UniProtKB-P49917


Protein	DNA ligase 4
Gene	LIG4
Status	Reviewed
Source	Colorectal cancer cell line, HCT-116 (colorectal cancer); Ovarian tumor; Prostate; Prostate tumor; Urine
Years	2007-2014

Glycosites

Site	Identified Peptides	Year(Publication ID)
648	APnLTNVNK	2007(58); 2011(14); 2014(unpublished);2007(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MAASQTSQTV	ASHVPFADLC	STLERIQKSK	GRAEKIRHFR	EFLDSWRKFH	DALHKNHKDV	TDSFYPAMRL	ILPQLERERM	AYGIKETMLA	KLYIELLNLP
101	111	121	131	141	151	161	171	181	191
RDGKDALKLL	NYRTPTGTHG	DAGDFAMIAY	FVLKPRCLQK	GSLTIQQVND	LLDSIASNNS	AKRKDLIKKS	LLQLITQSSA	LEQKWLIRMI	IKDLKLGVSQ
201	211	221	231	241	251	261	271	281	291
QTIFSVFHND	AAELHNVTTD	LEKVCRQLHD	PSVGLSDISI	TLFSAFKPML	AAIADIEHIE	KDMKHQSFYI	ETKLDGERMQ	MHKDGDVYKY	FSRNGYNYTD
301	311	321	331	341	351	361	371	381	391
QFGASPTEGS	LTPFIHNAFK	ADIQICILDG	EMMAYNPNTQ	TFMQKGTKFD	IKRMVEDSDL	QTCYCVFDVL	MVNNKKLGHE	TLRKRYEILS	SIFTPIPGRI
401	411	421	431	441	451	461	471	481	491
EIVQKTQAHT	KNEVIDALNE	AIDKREEGIM	VKQPLSIYKP	DKRGEGWLKI	KPEYVSGLMD	ELDILIVGGY	WGKGSRGGMM	SHFLCAVAEK	PPPGEKPSVF
501	511	521	531	541	551	561	571	581	591
HTLSRVGSGC	TMKELYDLGL	KLAKYWKPFH	RKAPPSSILC	GTEKPEVYIE	PCNSVIVQIK	AAEIVPSDMY	KTGCTLRFPR	IEKIRDDKEW	HECMTLDDLE
601	611	621	631	641	651	661	671	681	691
QLRGKASGKL	ASKHLYIGGD	DEPQEKKRKA	APKMKKVIGI	IEHLKAPNLT	NVNKISNIFE	DVEFCVMSGT	DSQPKPDLEN	RIAEFGGYIV	QNPGPDTYCV
701	711	721	731	741	751	761	771	781	791
IAGSENIRVK	NIILSNKHDV	VKPAWLLECF	KTKSFVPWQP	RFMIHMCPST	KEHFAREYDC	YGDSYFIDTD	LNQLKEVFSG	IKNSNEQTPE	EMASLIADLE
801	811	821	831	841	851	861	871	881	891
YRYSWDCSPL	SMFRRHTVYL	DSYAVINDLS	TKNEGTRLAI	KALELRFHGA	KVVSCLAEGV	SHVIIGEDHS	RVADFKAFRR	TFKRKFKILK	ESWVTDSIDK
901	911
CELQEENQYL	I

Reference

ID	Publication
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.
58	Nagano K, Shinkawa T, Kato K, Inomata N, Yabuki N, Haramura M: Distinct cell surface proteome profiling by biotin labeling and glycoprotein capturing. Journal of Proteomics 2011, 74:1985-1993.