Detail

UniProtKB-P51805


Protein	Plexin-A3
Gene	PLXNA3
Status	Reviewed
Source	Breast cancer xenografts; Colorectal tumor; DLBCL cell lines (Diffuse large B-cell lymphoma); HCC cell lines (Liver); HEK293 cell line (embryonic kidney); Hela cell line (cervical cancer); OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Pancreatic islets
Years	2012-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
59	IAPnITEIR	2014(16);
59	LAPnLTELR	2013(40); 2014(22); 2015(unpublished);2015(unpublished);2015(12);
1009	AnISSPGLIYTYTQDPTVTR	2014(15); 2015(unpublished);2015(1); 2015(unpublished);
1073	InDTAMLCK	2012(48);
1073	VInDTAMLCK	2012(48);
1073	GIETTNTCQVInDTAMLCK	2015(unpublished);

Sequence

1	11	21	31	41	51	61	71	81	91
MPSVCLLLLL	FLAVGGALGN	RPFRAFVVTD	TTLTHLAVHR	VTGEVFVGAV	NRVFKLAPNL	TELRAHVTGP	VEDNARCYPP	PSMRVCAHRL	APVDNINKLL
101	111	121	131	141	151	161	171	181	191
LIDYAARRLV	ACGSIWQGIC	QFLRLDDLFK	LGEPHHRKEH	YLSGAQEPDS	MAGVIVEQGQ	GPSKLFVGTA	VDGKSEYFPT	LSSRKLISDE	DSADMFSLVY
201	211	221	231	241	251	261	271	281	291
QDEFVSSQIK	IPSDTLSLYP	AFDIYYIYGF	VSASFVYFLT	LQLDTQQTLL	DTAGEKFFTS	KIVRMCAGDS	EFYSYVEFPI	GCSWRGVEYR	LVQSAHLAKP
301	311	321	331	341	351	361	371	381	391
GLLLAQALGV	PADEDVLFTI	FSQGQKNRAS	PPRQTILCLF	TLSNINAHIR	RRIQSCYRGE	GTLALPWLLN	KELPCINTPM	QINGNFCGLV	LNQPLGGLHV
401	411	421	431	441	451	461	471	481	491
IEGLPLLADS	TDGMASVAAY	TYRQHSVVFI	GTRSGSLKKV	RVDGFQDAHL	YETVPVVDGS	PILRDLLFSP	DHRHIYLLSE	KQVSQLPVET	CEQYQSCAAC
501	511	521	531	541	551	561	571	581	591
LGSGDPHCGW	CVLRHRCCRE	GACLGASAPH	GFAEELSKCV	QVRVRPNNVS	VTSPGVQLTV	TLHNVPDLSA	GVSCAFEAAA	ENEAVLLPSG	ELLCPSPSLQ
601	611	621	631	641	651	661	671	681	691
ELRALTRGHG	ATRTVRLQLL	SKETGVRFAG	ADFVFYNCSV	LQSCMSCVGS	PYPCHWCKYR	HTCTSRPHEC	SFQEGRVHSP	EGCPEILPSG	DLLIPVGVMQ
701	711	721	731	741	751	761	771	781	791
PLTLRAKNLP	QPQSGQKNYE	CVVRVQGRQQ	RVPAVRFNSS	SVQCQNASYS	YEGDEHGDTE	LDFSVVWDGD	FPIDKPPSFR	ALLYKCWAQR	PSCGLCLKAD
801	811	821	831	841	851	861	871	881	891
PRFNCGWCIS	EHRCQLRTHC	PAPKTNWMHL	SQKGTRCSHP	RITQIHPLVG	PKEGGTRVTI	VGDNLGLLSR	EVGLRVAGVR	CNSIPAEYIS	AERIVCEMEE
901	911	921	931	941	951	961	971	981	991
SLVPSPPPGP	VELCVGDCSA	DFRTQSEQVY	SFVTPTFDQV	SPSRGPASGG	TRLTISGSSL	DAGSRVTVTV	RDSECQFVRR	DAKAIVCISP	LSTLGPSQAP
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
ITLAIDRANI	SSPGLIYTYT	QDPTVTRLEP	TWSIINGSTA	ITVSGTHLLT	VQEPRVRAKY	RGIETTNTCQ	VINDTAMLCK	APGIFLGRPQ	PRAQGEHPDE
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
FGFLLDHVQT	ARSLNRSSFT	YYPDPSFEPL	GPSGVLDVKP	GSHVVLKGKN	LIPAAAGSSR	LNYTVLIGGQ	PCSLTVSDTQ	LLCDSPSQTG	RQPVMVLVGG
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
LEFWLGTLHI	SAERALTLPA	MMGLAAGGGL	LLLAITAVLV	AYKRKTQDAD	RTLKRLQLQM	DNLESRVALE	CKEAFAELQT	DINELTNHMD	EVQIPFLDYR
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
TYAVRVLFPG	IEAHPVLKEL	DTPPNVEKAL	RLFGQLLHSR	AFVLTFIHTL	EAQSSFSMRD	RGTVASLTMV	ALQSRLDYAT	GLLKQLLADL	IEKNLESKNH
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
PKLLLRRTES	VAEKMLTNWF	TFLLHKFLKE	CAGEPLFLLY	CAIKQQMEKG	PIDAITGEAR	YSLSEDKLIR	QQIDYKTLTL	HCVCPENEGS	AQVPVKVLNC
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
DSITQAKDKL	LDTVYKGIPY	SQRPKAEDMD	LEWRQGRMTR	IILQDEDVTT	KIECDWKRLN	SLAHYQVTDG	SLVALVPKQV	SAYNMANSFT	FTRSLSRYES
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
LLRTASSPDS	LRSRAPMITP	DQETGTKLWH	LVKNHDHADH	REGDRGSKMV	SEIYLTRLLA	TKGTLQKFVD	DLFETVFSTA	HRGSALPLAI	KYMFDFLDEQ
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
ADQRQISDPD	VRHTWKSNCL	PLRFWVNVIK	NPQFVFDIHK	NSITDACLSV	VAQTFMDSCS	TSEHRLGKDS	PSNKLLYAKD	IPNYKSWVER	YYRDIAKMAS
1801	1811	1821	1831	1841	1851	1861	1871
ISDQDMDAYL	VEQSRLHASD	FSVLSALNEL	YFYVTKYRQE	ILTALDRDAS	CRKHKLRQKL	EQIISLVSSD	S

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
12	Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5.
15	Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203.
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.