| Protein | Ephrin type-B receptor 3 |
| Gene | EPHB3 |
| Status | Reviewed |
| Source | 22Rv1 cell line (prostate cancer); ARO Cell Line (Thyroid Cance); Breast Cancer cell lines; Breast cancer cell lines; Breast cancer xenografts; Breast tumor; LNCap/PC3 cell lines (Prostate cancer); Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; Serum; Urine; ovarian tumor |
| Years | 2007-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 351 | GVISNVnETSLILEWSEPR | 2015(unpublished);2015(1); 2015(2); 2015(unpublished); |
| 445 | PRYAAVnITTNQA | 2013(37); |
| 445 | nITTNQAAPSEVPTLR | 2015(1); |
| 445 | YAAVnITTNQAAPSEVPTLR | 2007(62); 2009(40); 2010(54); 2011(50); 2012(45); 2013(18); 2014(1); 2015(2); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2007;2007;2007;2007;2007; |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MARARPPPPP | SPPPGLLPLL | PPLLLLPLLL | LPAGCRALEE | TLMDTKWVTS | ELAWTSHPES | GWEEVSGYDE | AMNPIRTYQV | CNVRESSQNN | WLRTGFIWRR |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| DVQRVYVELK | FTVRDCNSIP | NIPGSCKETF | NLFYYEADSD | VASASSPFWM | ENPYVKVDTI | APDESFSRLD | AGRVNTKVRS | FGPLSKAGFY | LAFQDQGACM |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| SLISVRAFYK | KCASTTAGFA | LFPETLTGAE | PTSLVIAPGT | CIPNAVEVSV | PLKLYCNGDG | EWMVPVGACT | CATGHEPAAK | ESQCRPCPPG | SYKAKQGEGP |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| CLPCPPNSRT | TSPAASICTC | HNNFYRADSD | SADSACTTVP | SPPRGVISNV | NETSLILEWS | EPRDLGGRDD | LLYNVICKKC | HGAGGASACS | RCDDNVEFVP |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| RQLGLTERRV | HISHLLAHTR | YTFEVQAVNG | VSGKSPLPPR | YAAVNITTNQ | AAPSEVPTLR | LHSSSGSSLT | LSWAPPERPN | GVILDYEMKY | FEKSEGIAST |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| VTSQMNSVQL | DGLRPDARYV | VQVRARTVAG | YGQYSRPAEF | ETTSERGSGA | QQLQEQLPLI | VGSATAGLVF | VVAVVVIAIV | CLRKQRHGSD | SEYTEKLQQY |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| IAPGMKVYID | PFTYEDPNEA | VREFAKEIDV | SCVKIEEVIG | AGEFGEVCRG | RLKQPGRREV | FVAIKTLKVG | YTERQRRDFL | SEASIMGQFD | HPNIIRLEGV |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| VTKSRPVMIL | TEFMENCALD | SFLRLNDGQF | TVIQLVGMLR | GIAAGMKYLS | EMNYVHRDLA | ARNILVNSNL | VCKVSDFGLS | RFLEDDPSDP | TYTSSLGGKI |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| PIRWTAPEAI | AYRKFTSASD | VWSYGIVMWE | VMSYGERPYW | DMSNQDVINA | VEQDYRLPPP | MDCPTALHQL | MLDCWVRDRN | LRPKFSQIVN | TLDKLIRNAA |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| SLKVIASAQS | GMSQPLLDRT | VPDYTTFTTV | GDWLDAIKMG | RYKESFVSAG | FASFDLVAQM | TAEDLLRIGV | TLAGHQKKIL | SSIQDMRLQM | NQTLPVQV |
| ID | Publication |
|---|---|
| 1 | Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication. |
| 2 | Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763. |
| 18 | Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |
| 45 | Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991. |
| 50 | Whitmore TE, Peterson A, Holzman T, Eastham A, Amon L, McIntosh M, Ozinsky A, Nelson PS, Martin DB: Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer. Journal of Proteome Research 2012, 11:2653-2665. |
| 54 | Tian Y, Yao Z, Roden R, Zhang H: Identification of glycoproteins associated with different histological subtypes of ovarian tumors using quantitative glycoproteomics. Proteomics 2011, 11:4677-4687. |
| 62 | Arcinas A, Yen T-Y, Kebebew E, Macher BA: Cell Surface and Secreted Protein Profiles of Human Thyroid Cancer Cell Lines Reveal Distinct Glycoprotein Patterns. Journal of Proteome Research 2009, 8:3958-3968. |