| Protein | A disintegrin and metalloproteinase with thrombospondin motifs 12 |
| Gene | ADAMTS12 |
| Status | Reviewed |
| Source | Breast Cancer cell lines; Breast cancer xenografts; HCC cell lines (Liver); Ovarian tumor |
| Years | 2013-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 125 | YGnLSHVK | 2015(unpublished);2015(unpublished); |
| 215 | DSVnISQK | 2015(unpublished); |
| 685 | MVGCDYEIDSnATEDR | 2013(40); |
| 1276 | LPNNMnQTK | 2015(unpublished); |
| 1276 | KIPNNMnQTKSSE | 2013(37); |
| 1301 | SSEPVLTEEDATSLITEGFLLnASNYK | 2015(unpublished); |
| 1372 | VGnWSK | 2015(unpublished);2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MPCAQRSWLA | NLSVVAQLLN | FGALCYGRQP | QPGPVRFPDR | RQEHFIKGLP | EYHVVGPVRV | DASGHFLSYG | LHYPITSSRR | KRDLDGSEDW | VYYRISHEEK |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| DLFFNLTVNQ | GFLSNSYIME | KRYGNLSHVK | MMASSAPLCH | LSGTVLQQGT | RVGTAALSAC | HGLTGFFQLP | HGDFFIEPVK | KHPLVEGGYH | PHIVYRRQKV |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| PETKEPTCGL | KDSVNISQKQ | ELWREKWERH | NLPSRSLSRR | SISKERWVET | LVVADTKMIE | YHGSENVESY | ILTIMNMVTG | LFHNPSIGNA | IHIVVVRLIL |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| LEEEEQGLKI | VHHAEKTLSS | FCKWQKSINP | KSDLNPVHHD | VAVLLTRKDI | CAGFNRPCET | LGLSHLSGMC | QPHRSCNINE | DSGLPLAFTI | AHELGHSFGI |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| QHDGKENDCE | PVGRHPYIMS | RQLQYDPTPL | TWSKCSEEYI | TRFLDRGWGF | CLDDIPKKKG | LKSKVIAPGV | IYDVHHQCQL | QYGPNATFCQ | EVENVCQTLW |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| CSVKGFCRSK | LDAAADGTQC | GEKKWCMAGK | CITVGKKPES | IPGGWGRWSP | WSHCSRTCGA | GVQSAERLCN | NPEPKFGGKY | CTGERKRYRL | CNVHPCRSEA |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| PTFRQMQCSE | FDTVPYKNEL | YHWFPIFNPA | HPCELYCRPI | DGQFSEKMLD | AVIDGTPCFE | GGNSRNVCIN | GICKMVGCDY | EIDSNATEDR | CGVCLGDGSS |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| CQTVRKMFKQ | KEGSGYVDIG | LIPKGARDIR | VMEIEGAGNF | LAIRSEDPEK | YYLNGGFIIQ | WNGNYKLAGT | VFQYDRKGDL | EKLMATGPTN | ESVWIQLLFQ |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| VTNPGIKYEY | TIQKDGLDND | VEQQMYFWQY | GHWTECSVTC | GTGIRRQTAH | CIKKGRGMVK | ATFCDPETQP | NGRQKKCHEK | ACPPRWWAGE | WEACSATCGP |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| HGEKKRTVLC | IQTMVSDEQA | LPPTDCQHLL | KPKTLLSCNR | DILCPSDWTV | GNWSECSVSC | GGGVRIRSVT | CAKNHDEPCD | VTRKPNSRAL | CGLQQCPSSR |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| RVLKPNKGTI | SNGKNPPTLK | PVPPPTSRPR | MLTTPTGPES | MSTSTPAISS | PSPTTASKEG | DLGGKQWQDS | STQPELSSRY | LISTGSTSQP | ILTSQSLSIQ |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| PSEENVSSSD | TGPTSEGGLV | ATTTSGSGLS | SSRNPITWPV | TPFYNTLTKG | PEMEIHSGSG | EEREQPEDKD | ESNPVIWTKI | RVPGNDAPVE | STEMPLAPPL |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| TPDLSRESWW | PPFSTVMEGL | LPSQRPTTSE | TGTPRVEGMV | TEKPANTLLP | LGGDHQPEPS | GKTANRNHLK | LPNNMNQTKS | SEPVLTEEDA | TSLITEGFLL |
| 1301 | 1311 | 1321 | 1331 | 1341 | 1351 | 1361 | 1371 | 1381 | 1391 |
| NASNYKQLTN | GHGSAHWIVG | NWSECSTTCG | LGAYWRRVEC | STQMDSDCAA | IQRPDPAKRC | HLRPCAGWKV | GNWSKCSRNC | SGGFKIREIQ | CVDSRDHRNL |
| 1401 | 1411 | 1421 | 1431 | 1441 | 1451 | 1461 | 1471 | 1481 | 1491 |
| RPFHCQFLAG | IPPPLSMSCN | PEPCEAWQVE | PWSQCSRSCG | GGVQERGVFC | PGGLCDWTKR | PTSTMSCNEH | LCCHWATGNW | DLCSTSCGGG | FQKRTVQCVP |
| 1501 | 1511 | 1521 | 1531 | 1541 | 1551 | 1561 | 1571 | 1581 | 1591 |
| SEGNKTEDQD | QCLCDHKPRP | PEFKKCNQQA | CKKSADLLCT | KDKLSASFCQ | TLKAMKKCSV | PTVRAECCFS | CPQTHITHTQ | RQRRQRLLQK | SKEL |
| ID | Publication |
|---|---|
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |