Contains      

UniProtKB-P62937

Protein Peptidyl-prolyl cis-trans isomerase A
Gene PPIA
Status Reviewed
Source Breast cancer xenografts; Colorectal cancer cell line, HCT-116 (colorectal cancer); Liver; Non-small Cell Lung Carcinoma; OVCAR-3 cell line (Ovarian cancer); Ovarian tumor; Prostate tumor; SW1990 cell line (Pancreatic cancer); Serum; Urine
Years 2007-2015

Glycosites

Site Identified Peptides Year(Publication ID)
71 RHnGTGGKSIY 2014(33);
71 TRHnGTGGKSIY 2014(33);
71 HnGTGGKSIYGEKFEDENFILK 2014(19);
108 nGSQFFICTA 2015(1);
108 nGSQFFLCTAK 2015(1);
108 SMANAGPNTnGSQF 2014(33);
108 SMANAGPNTnGSQFF 2014(33);
108 AGPNTnGSQFFICTAK 2015(unpublished);
108 AGPNTnGSQFFLCTAK 2007(unpublished);2007(unpublished);2007;
108 HTGPGILSMANAGPNTnG 2007(unpublished);2007(unpublished);2007(unpublished);2007;
108 HTGPGILSMANAGPNTnGSQF 2014(33);
108 HTGPGILSMANAGPNTnGSQFF 2014(19); 2014(33);
108 HTGPGILSMANAGPNTnGSQFFICTAK 2007(58); 2011(18); 2014(33); 2014(1); 2015(3); 2015(unpublished);2015(unpublished);2015;2007;2007;

Sequence

1112131415161718191
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSM
101111121131141151161
ANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE

Reference

ID Publication
1Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
3Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H: Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells. Clinical proteomics 2015, 12:11.
18Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
19Huang G, Sun Z, Qin H, Zhao L, Xiong Z, Peng X, Ou J, Zou H: Preparation of hydrazine functionalized polymer brushes hybrid magnetic nanoparticles for highly specific enrichment of glycopeptides. Analyst 2014, 139:2199-2206.
33Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
58Nagano K, Shinkawa T, Kato K, Inomata N, Yabuki N, Haramura M: Distinct cell surface proteome profiling by biotin labeling and glycoprotein capturing. Journal of Proteomics 2011, 74:1985-1993.