Detail

Contains

UniProtKB-Q01804


Protein	OTU domain-containing protein 4
Gene	OTUD4
Status	Reviewed
Source	Liver; OVCAR-3 cell line (Ovarian cancer)
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
479	nQSASQSSNPCVQR	2015(1);
479	DEQAFPALSSSSVnQSASQSSNPCVQR	2014(33);

Sequence

1	11	21	31	41	51	61	71	81	91
MEAAVGVPDG	GDQGGAGPRE	DATPMDAYLR	KLGLYRKLVA	KDGSCLFRAV	AEQVLHSQSR	HVEVRMACIH	YLRENREKFE	AFIEGSFEEY	LKRLENPQEW
101	111	121	131	141	151	161	171	181	191
VGQVEISALS	LMYRKDFIIY	REPNVSPSQV	TENNFPEKVL	LCFSNGNHYD	IVYPIKYKES	SAMCQSLLYE	LLYEKVFKTD	VSKIVMELDT	LEVADEDNSE
201	211	221	231	241	251	261	271	281	291
ISDSEDDSCK	SKTAAAAADV	NGFKPLSGNE	QLKNNGNSTS	LPLSRKVLKS	LNPAVYRNVE	YEIWLKSKQA	QQKRDYSIAA	GLQYEVGDKC	QVRLDHNGKF
301	311	321	331	341	351	361	371	381	391
LNADVQGIHS	ENGPVLVEEL	GKKHTSKNLK	APPPESWNTV	SGKKMKKPST	SGQNFHSDVD	YRGPKNPSKP	IKAPSALPPR	LQHPSGVRQH	AFSSHSSGSQ
401	411	421	431	441	451	461	471	481	491
SQKFSSEHKN	LSRTPSQIIR	KPDRERVEDF	DHTSRESNYF	GLSPEERREK	QAIEESRLLY	EIQNRDEQAF	PALSSSSVNQ	SASQSSNPCV	QRKSSHVGDR
501	511	521	531	541	551	561	571	581	591
KGSRRRMDTE	ERKDKDSIHG	HSQLDKRPEP	STLENITDDK	YATVSSPSKS	KKLECPSPAE	QKPAEHVSLS	NPAPLLVSPE	VHLTPAVPSL	PATVPAWPSE
601	611	621	631	641	651	661	671	681	691
PTTFGPTGVP	APIPVLSVTQ	TLTTGPDSAV	SQAHLTPSPV	PVSIQAVNQP	LMPLPQTLSL	YQDPLYPGFP	CNEKGDRAIV	PPYSLCQTGE	DLPKDKNILR
701	711	721	731	741	751	761	771	781	791
FFFNLGVKAY	SCPMWAPHSY	LYPLHQAYLA	ACRMYPKVPV	PVYPHNPWFQ	EAPAAQNESD	CTCTDAHFPM	QTEASVNGQM	PQPEIGPPTF	SSPLVIPPSQ
801	811	821	831	841	851	861	871	881	891
VSESHGQLSY	QADLESETPG	QLLHADYEES	LSGKNMFPQP	SFGPNPFLGP	VPIAPPFFPH	VWYGYPFQGF	IENPVMRQNI	VLPSDEKGEL	DLSLENLDLS
901	911	921	931	941	951	961	971	981	991
KDCGSVSTVD	EFPEARGEHV	HSLPEASVSS	KPDEGRTEQS	SQTRKADTAL	ASIPPVAEGK	AHPPTQILNR	ERETVPVELE	PKRTIQSLKE	KTEKVKDPKT
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
AADVVSPGAN	SVDSRVQRPK	EESSEDENEV	SNILRSGRSK	QFYNQTYGSR	KYKSDWGYSG	RGGYQHVRSE	ESWKGQPSRS	RDEGYQYHRN	VRGRPFRGDR
1101	1111
RRSGMGDGHR	GQHT

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.