Detail

UniProtKB-Q01973


Protein	Inactive tyrosine-protein kinase transmembrane receptor ROR1
Gene	ROR1
Status	Reviewed
Source	Breast Cancer cell lines; Breast cancer xenografts; DLBCL cell lines (Diffuse large B-cell lymphoma); HCC cell lines (Liver); Liver; Non-small Cell Lung Carcinoma; Pancreatic islets; Prostate tumor; Urine
Years	2007-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
66	LTLDEPMNnITTSLGQTAELHCK	2007(unpublished);2007(unpublished);2007;
66	DSYLTLDEPMNnITTSLGQTAELHCK	2012(48);
184	IGnRTVY	2014(33);
315	CYnSTGVDYR	2013(40); 2013(45); 2014(16); 2014(18); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);
315	KNHKCYnSTGVDY	2013(37);

Sequence

1	11	21	31	41	51	61	71	81	91
MHRPRRRGTR	PPLLALLAAL	LLAARGAAAQ	ETELSVSAEL	VPTSSWNISS	ELNKDSYLTL	DEPMNNITTS	LGQTAELHCK	VSGNPPPTIR	WFKNDAPVVQ
101	111	121	131	141	151	161	171	181	191
EPRRLSFRST	IYGSRLRIRN	LDTTDTGYFQ	CVATNGKEVV	SSTGVLFVKF	GPPPTASPGY	SDEYEEDGFC	QPYRGIACAR	FIGNRTVYME	SLHMQGEIEN
201	211	221	231	241	251	261	271	281	291
QITAAFTMIG	TSSHLSDKCS	QFAIPSLCHY	AFPYCDETSS	VPKPRDLCRD	ECEILENVLC	QTEYIFARSN	PMILMRLKLP	NCEDLPQPES	PEAANCIRIG
301	311	321	331	341	351	361	371	381	391
IPMADPINKN	HKCYNSTGVD	YRGTVSVTKS	GRQCQPWNSQ	YPHTHTFTAL	RFPELNGGHS	YCRNPGNQKE	APWCFTLDEN	FKSDLCDIPA	CDSKDSKEKN
401	411	421	431	441	451	461	471	481	491
KMEILYILVP	SVAIPLAIAL	LFFFICVCRN	NQKSSSAPVQ	RQPKHVRGQN	VEMSMLNAYK	PKSKAKELPL	SAVRFMEELG	ECAFGKIYKG	HLYLPGMDHA
501	511	521	531	541	551	561	571	581	591
QLVAIKTLKD	YNNPQQWTEF	QQEASLMAEL	HHPNIVCLLG	AVTQEQPVCM	LFEYINQGDL	HEFLIMRSPH	SDVGCSSDED	GTVKSSLDHG	DFLHIAIQIA
601	611	621	631	641	651	661	671	681	691
AGMEYLSSHF	FVHKDLAARN	ILIGEQLHVK	ISDLGLSREI	YSADYYRVQS	KSLLPIRWMP	PEAIMYGKFS	SDSDIWSFGV	VLWEIFSFGL	QPYYGFSNQE
701	711	721	731	741	751	761	771	781	791
VIEMVRKRQL	LPCSEDCPPR	MYSLMTECWN	EIPSRRPRFK	DIHVRLRSWE	GLSSHTSSTT	PSGGNATTQT	TSLSASPVSN	LSNPRYPNYM	FPSQGITPQG
801	811	821	831	841	851	861	871	881	891
QIAGFIGPPI	PQNQRFIPIN	GYPIPPGYAA	FPAAHYQPTG	PPRVIQHCPP	PKSRSPSSAS	GSTSTGHVTS	LPSSGSNQEA	NIPLLPHMSI	PNHPGGMGIT
901	911	921	931
VFGNKSQKPY	KIDSKQASLL	GDANIHGHTE	SMISAEL

Reference

ID	Publication
16	Deeb SJ, Cox J, Schmidt-Supprian M, Mann M: N-linked Glycosylation Enrichment for In-depth Cell Surface Proteomics of Diffuse Large B-cell Lymphoma Subtypes. Molecular & Cellular Proteomics 2014, 13:240-251.
18	Hirao Y, Matsuzaki H, Iwaki J, Kuno A, Kaji H, Ohkura T, Togayachi A, Abe M, Nomura M, Noguchi M, et al: Glycoproteomics Approach for Identifying Glycobiomarker Candidate Molecules for Tissue Type Classification of Non-small Cell Lung Carcinoma. Journal of Proteome Research 2014, 13:4705-4716.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.
37	Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171.
40	Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8.
45	Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991.
48	Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608.