Detail


Protein	Centromere-associated protein E
Gene	CENPE
Status	Reviewed
Source	Breast cancer xenografts; OVCAR-3 cell line (Ovarian cancer); Prostate tumor; Serum; Urine
Years	2007-2015

Site	Identified Peptides	Year(Publication ID)
79	nGTIFAYGQTASGK	2015(1);
1499	VnLSEK	2015(unpublished);
1637	MTAVnETQEKMCEIEHLK	2013(42);
1840	KDVnETQKKVSEME	2007(unpublished);2007(unpublished);2007;

Sequence

1	11	21	31	41	51	61	71	81	91
MAEEGAVAVC	VRVRPLNSRE	ESLGETAQVY	WKTDNNVIYQ	VDGSKSFNFD	RVFHGNETTK	NVYEEIAAPI	IDSAIQGYNG	TIFAYGQTAS	GKTYTMMGSE
101	111	121	131	141	151	161	171	181	191
DHLGVIPRAI	HDIFQKIKKF	PDREFLLRVS	YMEIYNETIT	DLLCGTQKMK	PLIIREDVNR	NVYVADLTEE	VVYTSEMALK	WITKGEKSRH	YGETKMNQRS
201	211	221	231	241	251	261	271	281	291
SRSHTIFRMI	LESREKGEPS	NCEGSVKVSH	LNLVDLAGSE	RAAQTGAAGV	RLKEGCNINR	SLFILGQVIK	KLSDGQVGGF	INYRDSKLTR	ILQNSLGGNA
301	311	321	331	341	351	361	371	381	391
KTRIICTITP	VSFDETLTAL	QFASTAKYMK	NTPYVNEVST	DEALLKRYRK	EIMDLKKQLE	EVSLETRAQA	MEKDQLAQLL	EEKDLLQKVQ	NEKIENLTRM
401	411	421	431	441	451	461	471	481	491
LVTSSSLTLQ	QELKAKRKRR	VTWCLGKINK	MKNSNYADQF	NIPTNITTKT	HKLSINLLRE	IDESVCSESD	VFSNTLDTLS	EIEWNPATKL	LNQENIESEL
501	511	521	531	541	551	561	571	581	591
NSLRADYDNL	VLDYEQLRTE	KEEMELKLKE	KNDLDEFEAL	ERKTKKDQEM	QLIHEISNLK	NLVKHAEVYN	QDLENELSSK	VELLREKEDQ	IKKLQEYIDS
601	611	621	631	641	651	661	671	681	691
QKLENIKMDL	SYSLESIEDP	KQMKQTLFDA	ETVALDAKRE	SAFLRSENLE	LKEKMKELAT	TYKQMENDIQ	LYQSQLEAKK	KMQVDLEKEL	QSAFNEITKL
701	711	721	731	741	751	761	771	781	791
TSLIDGKVPK	DLLCNLELEG	KITDLQKELN	KEVEENEALR	EEVILLSELK	SLPSEVERLR	KEIQDKSEEL	HIITSEKDKL	FSEVVHKESR	VQGLLEEIGK
801	811	821	831	841	851	861	871	881	891
TKDDLATTQS	NYKSTDQEFQ	NFKTLHMDFE	QKYKMVLEEN	ERMNQEIVNL	SKEAQKFDSS	LGALKTELSY	KTQELQEKTR	EVQERLNEME	QLKEQLENRD
901	911	921	931	941	951	961	971	981	991
STLQTVEREK	TLITEKLQQT	LEEVKTLTQE	KDDLKQLQES	LQIERDQLKS	DIHDTVNMNI	DTQEQLRNAL	ESLKQHQETI	NTLKSKISEE	VSRNLHMEEN
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
TGETKDEFQQ	KMVGIDKKQD	LEAKNTQTLT	ADVKDNEIIE	QQRKIFSLIQ	EKNELQQMLE	SVIAEKEQLK	TDLKENIEMT	IENQEELRLL	GDELKKQQEI
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
VAQEKNHAIK	KEGELSRTCD	RLAEVEEKLK	EKSQQLQEKQ	QQLLNVQEEM	SEMQKKINEI	ENLKNELKNK	ELTLEHMETE	RLELAQKLNE	NYEEVKSITK
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
ERKVLKELQK	SFETERDHLR	GYIREIEATG	LQTKEELKIA	HIHLKEHQET	IDELRRSVSE	KTAQIINTQD	LEKSHTKLQE	EIPVLHEEQE	LLPNVKEVSE
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
TQETMNELEL	LTEQSTTKDS	TTLARIEMER	LRLNEKFQES	QEEIKSLTKE	RDNLKTIKEA	LEVKHDQLKE	HIRETLAKIQ	ESQSKQEQSL	NMKEKDNETT
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
KIVSEMEQFK	PKDSALLRIE	IEMLGLSKRL	QESHDEMKSV	AKEKDDLQRL	QEVLQSESDQ	LKENIKEIVA	KHLETEEELK	VAHCCLKEQE	ETINELRVNL
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
SEKETEISTI	QKQLEAINDK	LQNKIQEIYE	KEEQFNIKQI	SEVQEKVNEL	KQFKEHRKAK	DSALQSIESK	MLELTNRLQE	SQEEIQIMIK	EKEEMKRVQE
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
ALQIERDQLK	ENTKEIVAKM	KESQEKEYQF	LKMTAVNETQ	EKMCEIEHLK	EQFETQKLNL	ENIETENIRL	TQILHENLEE	MRSVTKERDD	LRSVEETLKV
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
ERDQLKENLR	ETITRDLEKQ	EELKIVHMHL	KEHQETIDKL	RGIVSEKTNE	ISNMQKDLEH	SNDALKAQDL	KIQEELRIAH	MHLKEQQETI	DKLRGIVSEK
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
TDKLSNMQKD	LENSNAKLQE	KIQELKANEH	QLITLKKDVN	ETQKKVSEME	QLKKQIKDQS	LTLSKLEIEN	LNLAQKLHEN	LEEMKSVMKE	RDNLRRVEET
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
LKLERDQLKE	SLQETKARDL	EIQQELKTAR	MLSKEHKETV	DKLREKISEK	TIQISDIQKD	LDKSKDELQK	KIQELQKKEL	QLLRVKEDVN	MSHKKINEME
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
QLKKQFEAQN	LSMQSVRMDN	FQLTKKLHES	LEEIRIVAKE	RDELRRIKES	LKMERDQFIA	TLREMIARDR	QNHQVKPEKR	LLSDGQQHLT	ESLREKCSRI
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
KELLKRYSEM	DDHYECLNRL	SLDLEKEIEF	QKELSMRVKA	NLSLPYLQTK	HIEKLFTANQ	RCSMEFHRIM	KKLKYVLSYV	TKIKEEQHES	INKFEMDFID
2201	2211	2221	2231	2241	2251	2261	2271	2281	2291
EVEKQKELLI	KIQHLQQDCD	VPSRELRDLK	LNQNMDLHIE	EILKDFSESE	FPSIKTEFQQ	VLSNRKEMTQ	FLEEWLNTRF	DIEKLKNGIQ	KENDRICQVN
2301	2311	2321	2331	2341	2351	2361	2371	2381	2391
NFFNNRIIAI	MNESTEFEER	SATISKEWEQ	DLKSLKEKNE	KLFKNYQTLK	TSLASGAQVN	PTTQDNKNPH	VTSRATQLTT	EKIRELENSL	HEAKESAMHK
2401	2411	2421	2431	2441	2451	2461	2471	2481	2491
ESKIIKMQKE	LEVTNDIIAK	LQAKVHESNK	CLEKTKETIQ	VLQDKVALGA	KPYKEEIEDL	KMKLVKIDLE	KMKNAKEFEK	EISATKATVE	YQKEVIRLLR
2501	2511	2521	2531	2541	2551	2561	2571	2581	2591
ENLRRSQQAQ	DTSVISEHTD	PQPSNKPLTC	GGGSGIVQNT	KALILKSEHI	RLEKEISKLK	QQNEQLIKQK	NELLSNNQHL	SNEVKTWKER	TLKREAHKQV
2601	2611	2621	2631	2641	2651	2661	2671	2681	2691
TCENSPKSPK	VTGTASKKKQ	ITPSQCKERN	LQDPVPKESP	KSCFFDSRSK	SLPSPHPVRY	FDNSSLGLCP	EVQNAGAESV	DSQPGPWHAS	SGKDVPECKT
2701
Q

UniProtKB-Q02224

Glycosites

Sequence

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
42	Ma C, Zhao X, Han H, Tong W, Zhang Q, Qin P, Chang C, Peng B, Ying W, Qian X: N-linked glycoproteome profiling of human serum using tandem enrichment and multiple fraction concatenation. Electrophoresis 2013, 34:2440-2450.