| Protein | Collagen alpha-1(VII) chain |
| Gene | COL7A1 |
| Status | Reviewed |
| Source | Breast Cancer cell lines; Breast cancer xenografts; Breast cell lines; HCC cell lines (Liver); Hela cell line (cervical cancer); Liver; Ovarian tumor; Urine |
| Years | 2012-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 337 | LTIQnTTAHSLLVAWR | 2014(33); |
| 337 | TTALEGPELTIQnTTAHSLLVAWR | 2012(52); 2014(33); |
| 786 | LQILnASSDVLR | 2012(52); 2013(40); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015(12); |
| 786 | SRIQIInASSDVI | 2013(37); |
| 1109 | PSPLFPLnGSHDLGIILQR | 2015(unpublished); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MTLRLLVAAL | CAGILAEAPR | VRAQHRERVT | CTRLYAADIV | FLLDGSSSIG | RSNFREVRSF | LEGLVLPFSG | AASAQGVRFA | TVQYSDDPRT | EFGLDALGSG |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| GDVIRAIREL | SYKGGNTRTG | AAILHVADHV | FLPQLARPGV | PKVCILITDG | KSQDLVDTAA | QRLKGQGVKL | FAVGIKNADP | EELKRVASQP | TSDFFFFVND |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| FSILRTLLPL | VSRRVCTTAG | GVPVTRPPDD | STSAPRDLVL | SEPSSQSLRV | QWTAASGPVT | GYKVQYTPLT | GLGQPLPSER | QEVNVPAGET | SVRLRGLRPL |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| TEYQVTVIAL | YANSIGEAVS | GTARTTALEG | PELTIQNTTA | HSLLVAWRSV | PGATGYRVTW | RVLSGGPTQQ | QELGPGQGSV | LLRDLEPGTD | YEVTVSTLFG |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| RSVGPATSLM | ARTDASVEQT | LRPVILGPTS | ILLSWNLVPE | ARGYRLEWRR | ETGLEPPQKV | VLPSDVTRYQ | LDGLQPGTEY | RLTLYTLLEG | HEVATPATVV |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| PTGPELPVSP | VTDLQATELP | GQRVRVSWSP | VPGATQYRII | VRSTQGVERT | LVLPGSQTAF | DLDDVQAGLS | YTVRVSARVG | PREGSASVLT | VRREPETPLA |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| VPGLRVVVSD | ATRVRVAWGP | VPGASGFRIS | WSTGSGPESS | QTLPPDSTAT | DITGLQPGTT | YQVAVSVLRG | REEGPAAVIV | ARTDPLGPVR | TVHVTQASSS |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| SVTITWTRVP | GATGYRVSWH | SAHGPEKSQL | VSGEATVAEL | DGLEPDTEYT | VHVRAHVAGV | DGPPASVVVR | TAPEPVGRVS | RLQILNASSD | VLRITWVGVT |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| GATAYRLAWG | RSEGGPMRHQ | ILPGNTDSAE | IRGLEGGVSY | SVRVTALVGD | REGTPVSIVV | TTPPEAPPAL | GTLHVVQRGE | HSLRLRWEPV | PRAQGFLLHW |
| 901 | 911 | 921 | 931 | 941 | 951 | 961 | 971 | 981 | 991 |
| QPEGGQEQSR | VLGPELSSYH | LDGLEPATQY | RVRLSVLGPA | GEGPSAEVTA | RTESPRVPSI | ELRVVDTSID | SVTLAWTPVS | RASSYILSWR | PLRGPGQEVP |
| 1001 | 1011 | 1021 | 1031 | 1041 | 1051 | 1061 | 1071 | 1081 | 1091 |
| GSPQTLPGIS | SSQRVTGLEP | GVSYIFSLTP | VLDGVRGPEA | SVTQTPVCPR | GLADVVFLPH | ATQDNAHRAE | ATRRVLERLV | LALGPLGPQA | VQVGLLSYSH |
| 1101 | 1111 | 1121 | 1131 | 1141 | 1151 | 1161 | 1171 | 1181 | 1191 |
| RPSPLFPLNG | SHDLGIILQR | IRDMPYMDPS | GNNLGTAVVT | AHRYMLAPDA | PGRRQHVPGV | MVLLVDEPLR | GDIFSPIREA | QASGLNVVML | GMAGADPEQL |
| 1201 | 1211 | 1221 | 1231 | 1241 | 1251 | 1261 | 1271 | 1281 | 1291 |
| RRLAPGMDSV | QTFFAVDDGP | SLDQAVSGLA | TALCQASFTT | QPRPEPCPVY | CPKGQKGEPG | EMGLRGQVGP | PGDPGLPGRT | GAPGPQGPPG | SATAKGERGF |
| 1301 | 1311 | 1321 | 1331 | 1341 | 1351 | 1361 | 1371 | 1381 | 1391 |
| PGADGRPGSP | GRAGNPGTPG | APGLKGSPGL | PGPRGDPGER | GPRGPKGEPG | APGQVIGGEG | PGLPGRKGDP | GPSGPPGPRG | PLGDPGPRGP | PGLPGTAMKG |
| 1401 | 1411 | 1421 | 1431 | 1441 | 1451 | 1461 | 1471 | 1481 | 1491 |
| DKGDRGERGP | PGPGEGGIAP | GEPGLPGLPG | SPGPQGPVGP | PGKKGEKGDS | EDGAPGLPGQ | PGSPGEQGPR | GPPGAIGPKG | DRGFPGPLGE | AGEKGERGPP |
| 1501 | 1511 | 1521 | 1531 | 1541 | 1551 | 1561 | 1571 | 1581 | 1591 |
| GPAGSRGLPG | VAGRPGAKGP | EGPPGPTGRQ | GEKGEPGRPG | DPAVVGPAVA | GPKGEKGDVG | PAGPRGATGV | QGERGPPGLV | LPGDPGPKGD | PGDRGPIGLT |
| 1601 | 1611 | 1621 | 1631 | 1641 | 1651 | 1661 | 1671 | 1681 | 1691 |
| GRAGPPGDSG | PPGEKGDPGR | PGPPGPVGPR | GRDGEVGEKG | DEGPPGDPGL | PGKAGERGLR | GAPGVRGPVG | EKGDQGDPGE | DGRNGSPGSS | GPKGDRGEPG |
| 1701 | 1711 | 1721 | 1731 | 1741 | 1751 | 1761 | 1771 | 1781 | 1791 |
| PPGPPGRLVD | TGPGAREKGE | PGDRGQEGPR | GPKGDPGLPG | APGERGIEGF | RGPPGPQGDP | GVRGPAGEKG | DRGPPGLDGR | SGLDGKPGAA | GPSGPNGAAG |
| 1801 | 1811 | 1821 | 1831 | 1841 | 1851 | 1861 | 1871 | 1881 | 1891 |
| KAGDPGRDGL | PGLRGEQGLP | GPSGPPGLPG | KPGEDGKPGL | NGKNGEPGDP | GEDGRKGEKG | DSGASGREGR | DGPKGERGAP | GILGPQGPPG | LPGPVGPPGQ |
| 1901 | 1911 | 1921 | 1931 | 1941 | 1951 | 1961 | 1971 | 1981 | 1991 |
| GFPGVPGGTG | PKGDRGETGS | KGEQGLPGER | GLRGEPGSVP | NVDRLLETAG | IKASALREIV | ETWDESSGSF | LPVPERRRGP | KGDSGEQGPP | GKEGPIGFPG |
| 2001 | 2011 | 2021 | 2031 | 2041 | 2051 | 2061 | 2071 | 2081 | 2091 |
| ERGLKGDRGD | PGPQGPPGLA | LGERGPPGPS | GLAGEPGKPG | IPGLPGRAGG | VGEAGRPGER | GERGEKGERG | EQGRDGPPGL | PGTPGPPGPP | GPKVSVDEPG |
| 2101 | 2111 | 2121 | 2131 | 2141 | 2151 | 2161 | 2171 | 2181 | 2191 |
| PGLSGEQGPP | GLKGAKGEPG | SNGDQGPKGD | RGVPGIKGDR | GEPGPRGQDG | NPGLPGERGM | AGPEGKPGLQ | GPRGPPGPVG | GHGDPGPPGA | PGLAGPAGPQ |
| 2201 | 2211 | 2221 | 2231 | 2241 | 2251 | 2261 | 2271 | 2281 | 2291 |
| GPSGLKGEPG | ETGPPGRGLT | GPTGAVGLPG | PPGPSGLVGP | QGSPGLPGQV | GETGKPGAPG | RDGASGKDGD | RGSPGVPGSP | GLPGPVGPKG | EPGPTGAPGQ |
| 2301 | 2311 | 2321 | 2331 | 2341 | 2351 | 2361 | 2371 | 2381 | 2391 |
| AVVGLPGAKG | EKGAPGGLAG | DLVGEPGAKG | DRGLPGPRGE | KGEAGRAGEP | GDPGEDGQKG | APGPKGFKGD | PGVGVPGSPG | PPGPPGVKGD | LGLPGLPGAP |
| 2401 | 2411 | 2421 | 2431 | 2441 | 2451 | 2461 | 2471 | 2481 | 2491 |
| GVVGFPGQTG | PRGEMGQPGP | SGERGLAGPP | GREGIPGPLG | PPGPPGSVGP | PGASGLKGDK | GDPGVGLPGP | RGERGEPGIR | GEDGRPGQEG | PRGLTGPPGS |
| 2501 | 2511 | 2521 | 2531 | 2541 | 2551 | 2561 | 2571 | 2581 | 2591 |
| RGERGEKGDV | GSAGLKGDKG | DSAVILGPPG | PRGAKGDMGE | RGPRGLDGDK | GPRGDNGDPG | DKGSKGEPGD | KGSAGLPGLR | GLLGPQGQPG | AAGIPGDPGS |
| 2601 | 2611 | 2621 | 2631 | 2641 | 2651 | 2661 | 2671 | 2681 | 2691 |
| PGKDGVPGIR | GEKGDVGFMG | PRGLKGERGV | KGACGLDGEK | GDKGEAGPPG | RPGLAGHKGE | MGEPGVPGQS | GAPGKEGLIG | PKGDRGFDGQ | PGPKGDQGEK |
| 2701 | 2711 | 2721 | 2731 | 2741 | 2751 | 2761 | 2771 | 2781 | 2791 |
| GERGTPGIGG | FPGPSGNDGS | AGPPGPPGSV | GPRGPEGLQG | QKGERGPPGE | RVVGAPGVPG | APGERGEQGR | PGPAGPRGEK | GEAALTEDDI | RGFVRQEMSQ |
| 2801 | 2811 | 2821 | 2831 | 2841 | 2851 | 2861 | 2871 | 2881 | 2891 |
| HCACQGQFIA | SGSRPLPSYA | ADTAGSQLHA | VPVLRVSHAE | EEERVPPEDD | EYSEYSEYSV | EEYQDPEAPW | DSDDPCSLPL | DEGSCTAYTL | RWYHRAVTGS |
| 2901 | 2911 | 2921 | 2931 | 2941 | |||||
| TEACHPFVYG | GCGGNANRFG | TREACERRCP | PRVVQSQGTG | TAQD |
| ID | Publication |
|---|---|
| 12 | Weng Y, Sui Z, Jiang H, Shan Y, Chen L, Zhang S, Zhang L, Zhang Y: Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation. Scientific Reports 2015, 5. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 40 | Li X, Jiang J, Zhao X, Wang J, Han H, Zhao Y, Peng B, Zhong R, Ying W, Qian X: N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry. Plos One 2013, 8. |
| 52 | Yen T-Y, Macher BA, McDonald CA, Alleyne-Chin C, Timpe LC: Glycoprotein Profiles of Human Breast Cells Demonstrate a Clear Clustering of Normal/Benign versus Malignant Cell Lines and Basal versus Luminal Cell Lines. Journal of Proteome Research 2012, 11:656-667. |