| Protein | Glutamate carboxypeptidase 2 |
| Gene | FOLH1 |
| Status | Reviewed |
| Source | 22Rv1 cell line (prostate cancer); 22Rv1 cell xenograft (prostate cancer); Breast cancer xenografts; LNCap/PC3 cell lines (Prostate cancer); Liver; Liver tumor (HCC); LnCap cell line (Prostate cancer); Ovarian tumor; Prostate; Prostate cancer cell lines; Prostate tumor; Serum; Spermatozoa; Urine |
| Years | 2003-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 51 | SSNEATnITPK | 2014(14); |
| 76 | nFTQIPHLAGTEQNF | 2014(33); |
| 76 | LYnFTQIPHLAGTEQNF | 2014(33); |
| 76 | FIYnFTQIPHIAGTEQNFQIAK | 2013(43); |
| 76 | FLYnFTQIPHLAGTEQNFQLAK | 2003( 83); 2014(14); 2014(33); 2015(2); 2015(unpublished);2015(unpublished);2007(unpublished);2007;2007; |
| 76 | KFLYnFTQIPHLAGTEQNFQLAK | 2015(2); |
| 121 | LAHYDVLLSYPnK | 2014(33); |
| 121 | EFGLDSVELAHYDVLLSYPnK | 2015(2); |
| 195 | InCSGK | 2015(2); |
| 336 | NVGPGFTGnFSTQ | 2014(33); |
| 336 | NVGPGFTGnFSTQK | 2007(unpublished);2014(14); 2014(33); 2015(unpublished); |
| 336 | YNVGPGFTGnFSTQK | 2014(14); 2015(unpublished); |
| 336 | VPYNVGPGFTGnFSTQK | 2003( 83); 2012(50); 2012(50); 2013(43); 2014(14); 2014(32); 2014(32); 2014(33); 2015(2); 2015(unpublished);2015(unpublished);2015;2015;2015;2015;2007;2007; |
| 336 | GSLKVPYNVGPGFTGnFSTQK | 2014(14); 2014(33); 2015(2); 2015(unpublished); |
| 459 | GnYTLR | 2014(33); |
| 459 | INADSSIEGnY | 2014(33); |
| 459 | ADSSIEGnYTLR | 2014(14); |
| 459 | NADSSIEGnYTLR | 2014(14); |
| 459 | INADSSIEGnYTLR | 2014(14); 2014(33); 2015(unpublished); |
| 459 | AYINADSSIEGnYTLR | 2014(14); 2015(unpublished); |
| 459 | GVAYINADSSIEGnYTLR | 2003(83); 2012(50); 2014(14); 2015(2); 2015(unpublished);2015(unpublished);2015(unpublished); |
| 476 | SLVHnLTK | 2014(14); 2014(33); 2015(unpublished);2015(unpublished); |
| 476 | SLVHnLTKEL | 2014(33); |
| 476 | VDCTPIMYSIVHnITK | 2013(43); 2014(32); |
| 476 | VDCTPLMYSLVHnLTK | 2003(83); 2014(14); 2014(33); 2015(unpublished);2015(2); 2015(unpublished);2015(unpublished);2015(unpublished); |
| 638 | nFTEIASK | 2012(50); 2014(14); 2014(33); 2015(2); 2015(unpublished);2015;2015;2015;2015;2007; |
| 638 | SAVKnFTEIASKF | 2014(33); |
| 638 | TYSVSFDSLFSAVKnFTEIASK | 2003(83); 2015(2); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MWNLLHETDS | AVATARRPRW | LCAGALVLAG | GFFLLGFLFG | WFIKSSNEAT | NITPKHNMKA | FLDELKAENI | KKFLYNFTQI | PHLAGTEQNF | QLAKQIQSQW |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| KEFGLDSVEL | AHYDVLLSYP | NKTHPNYISI | INEDGNEIFN | TSLFEPPPPG | YENVSDIVPP | FSAFSPQGMP | EGDLVYVNYA | RTEDFFKLER | DMKINCSGKI |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| VIARYGKVFR | GNKVKNAQLA | GAKGVILYSD | PADYFAPGVK | SYPDGWNLPG | GGVQRGNILN | LNGAGDPLTP | GYPANEYAYR | RGIAEAVGLP | SIPVHPIGYY |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| DAQKLLEKMG | GSAPPDSSWR | GSLKVPYNVG | PGFTGNFSTQ | KVKMHIHSTN | EVTRIYNVIG | TLRGAVEPDR | YVILGGHRDS | WVFGGIDPQS | GAAVVHEIVR |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| SFGTLKKEGW | RPRRTILFAS | WDAEEFGLLG | STEWAEENSR | LLQERGVAYI | NADSSIEGNY | TLRVDCTPLM | YSLVHNLTKE | LKSPDEGFEG | KSLYESWTKK |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| SPSPEFSGMP | RISKLGSGND | FEVFFQRLGI | ASGRARYTKN | WETNKFSGYP | LYHSVYETYE | LVEKFYDPMF | KYHLTVAQVR | GGMVFELANS | IVLPFDCRDY |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| AVVLRKYADK | IYSISMKHPQ | EMKTYSVSFD | SLFSAVKNFT | EIASKFSERL | QDFDKSNPIV | LRMMNDQLMF | LERAFIDPLG | LPDRPFYRHV | IYAPSSHNKY |
| 701 | 711 | 721 | 731 | 741 | |||||
| AGESFPGIYD | ALFDIESKVD | PSKAWGEVKR | QIYVAAFTVQ | AAAETLSEVA |
| ID | Publication |
|---|---|
| 2 | Shah P, Wang X, Yang W, Eshghi ST, Sun S, Hoti N, Chen L, Yang S, Pasay J, Rubin A: Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveal Glycoprotein Alteration in Protein Abundance and Glycosylation. Molecular & Cellular Proteomics 2015, 14:2753-2763. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 43 | Wang GG, Wu YB, Zhou T, Guo YS, Zheng B, Wang J, Bi Y, Liu FJ, Zhou ZM, Guo XJ, Sha JH: Mapping of the N-Linked Glycoproteome of Human Spermatozoa. Journal of Proteome Research 2013, 12:5750-5759. |
| 50 | Whitmore TE, Peterson A, Holzman T, Eastham A, Amon L, McIntosh M, Ozinsky A, Nelson PS, Martin DB: Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer. Journal of Proteome Research 2012, 11:2653-2665. |
| 83 | Zhang H, Li XJ, Martin DB, Aebersold R: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. Nature Biotechnology 2003, 21:660-666. |