Detail

Contains

UniProtKB-Q05209


Protein	Tyrosine-protein phosphatase non-receptor type 12
Gene	PTPN12
Status	Reviewed
Source	OVCAR-3 cell line (Ovarian cancer); Prostate
Years	2014-2015

Glycosites

Site	Identified Peptides	Year(Publication ID)
433	nLSFEIK	2014(14);
554	nSSDINYQTR	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
MEQVEILRKF	IQRVQAMKSP	DHNGEDNFAR	DFMRLRRLST	KYRTEKIYPT	ATGEKEENVK	KNRYKDILPF	DHSRVKLTLK	TPSQDSDYIN	ANFIKGVYGP
101	111	121	131	141	151	161	171	181	191
KAYVATQGPL	ANTVIDFWRM	IWEYNVVIIV	MACREFEMGR	KKCERYWPLY	GEDPITFAPF	KISCEDEQAR	TDYFIRTLLL	EFQNESRRLY	QFHYVNWPDH
201	211	221	231	241	251	261	271	281	291
DVPSSFDSIL	DMISLMRKYQ	EHEDVPICIH	CSAGCGRTGA	ICAIDYTWNL	LKAGKIPEEF	NVFNLIQEMR	TQRHSAVQTK	EQYELVHRAI	AQLFEKQLQL
301	311	321	331	341	351	361	371	381	391
YEIHGAQKIA	DGVNEINTEN	MVSSIEPEKQ	DSPPPKPPRT	RSCLVEGDAK	EEILQPPEPH	PVPPILTPSP	PSAFPTVTTV	WQDNDRYHPK	PVLHMVSSEQ
401	411	421	431	441	451	461	471	481	491
HSADLNRNYS	KSTELPGKNE	STIEQIDKKL	ERNLSFEIKK	VPLQEGPKSF	DGNTLLNRGH	AIKIKSASPC	IADKISKPQE	LSSDLNVGDT	SQNSCVDCSV
501	511	521	531	541	551	561	571	581	591
TQSNKVSVTP	PEESQNSDTP	PRPDRLPLDE	KGHVTWSFHG	PENAIPIPDL	SEGNSSDINY	QTRKTVSLTP	SPTTQVETPD	LVDHDNTSPL	FRTPLSFTNP
601	611	621	631	641	651	661	671	681	691
LHSDDSDSDE	RNSDGAVTQN	KTNISTASAT	VSAATSTESI	STRKVLPMSI	ARHNIAGTTH	SGAEKDVDVS	EDSPPPLPER	TPESFVLASE	HNTPVRSEWS
701	711	721	731	741	751	761	771
ELQSQERSEQ	KKSEGLITSE	NEKCDHPAGG	IHYEMCIECP	PTFSDKREQI	SENPTEATDI	GFGNRCGKPK	GPRDPPSEWT

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
14	Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768.