| Protein | Glutamyl aminopeptidase |
| Gene | ENPEP |
| Status | Reviewed |
| Source | Breast Cancer cell lines; Colorectal tumor; HEK293 cell line (embryonic kidney); HEK293T cell line (embryonic kidney), HEK293T cell line (embryonic kidney); Human; Liver; Liver tumor (HCC); Ovarian tumor; Pancreatic islets; Plasma; Prostate; Prostate tumor; Serum; Urine |
| Years | 2005-2015 |
| Site | Identified Peptides | Year(Publication ID) |
|---|---|---|
| 124 | ISInLSAPTR | 2007(unpublished);2007(unpublished);2007; |
| 124 | ISInLSAPTRY | 2009(64); |
| 197 | LnGSLVGFYR | 2014(33); |
| 197 | AGWLnGSLVGFY | 2014(33); |
| 197 | AGWLnGSLVGFYR | 2014(33); |
| 197 | FAGWLnGSLVGFYR | 2014(33); |
| 324 | YAAnITK | 2014(33); |
| 324 | AAnITKSVF | 2014(33); |
| 324 | YAAnITKSVF | 2009(64); |
| 324 | HTAEYAAnITK | 2007(64); 2009(48); 2012(45); 2013(13); 2014(14); 2014(15); 2014(22); 2014(33); 2014(9); 2015(unpublished);2015(unpublished);2015;2015;2015;2007;2007; |
| 324 | TAEYAAnITKSVF | 2013(37); |
| 324 | AAnITKSVFDYFEEY | 2014(33); |
| 340 | FAMnYSLPK | 2007(unpublished);2007(unpublished);2007; |
| 340 | YFAMnYSLPK | 2014(33); |
| 554 | GVKnITQKRF | 2014(33); |
| 554 | QMGYPVLNVNGVKnITQK | 2015(unpublished);2015(unpublished); |
| 554 | QMGYPVLNVNGVKnITQKR | 2014(33); |
| 589 | TEDnITSSVLF | 2014(33); |
| 589 | WTEDnITSSVLF | 2014(33); |
| 589 | WTEDnITSSVIFNR | 2014(32); 2014(32); |
| 589 | WTEDnITSSVLFNR | 2012(48); 2013(45); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished); |
| 589 | NIPVKWTEDnITSSVLF | 2014(33); |
| 597 | WTEDNITSSVIFnR | 2014(32); 2014(32); |
| 597 | WTEDNITSSVLFnR | 2012(48); 2013(45); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished);2015(unpublished); |
| 607 | GITLnSSNPSGNAFLK | 2014(33); |
| 607 | EGITInSSNPSGNAFIK | 2014(32); |
| 607 | EGITLnSSNPSGNAFLK | 2005( 81); 2007(64); 2009(48); 2012(45); 2013(14); 2014(15); 2014(22); 2014(33); 2014(unpublished);2015(unpublished);2015(unpublished);2015(unpublished);2015;2015;2007;2007;2007;2007; |
| 607 | SEKEGITLnSSNPSGNAFLK | 2013(45); 2014(33); 2015(unpublished);2015(unpublished);2015(unpublished); |
| 678 | VALnLTK | 2007(14); 2014(22); 2014(33); 2014(unpublished);2015(unpublished);2015;2015;2015;2007;2007; |
| 678 | VALnLTKY | 2014(33); |
| 678 | KVALnLTKY | 2014(33); |
| 678 | DYKVALnLTKY | 2014(33); |
| 678 | AQLLDYKVALnLTK | 2014(33); |
| 763 | EALNnASSLF | 2014(33); |
| 763 | EALNnASSLFE | 2014(33); |
| 763 | nASSLFEQWLNGTVSLPVNL | 2015(6); |
| 763 | NnASSLFEQWLNGTVSLPVNL | 2014(33); |
| 763 | EALNnASSLFEQWLNGTVSLPVNLR | 2009(64); 2014(33); |
| 773 | LnGTVSLPVNLR | 2014(33); |
| 773 | QWLnGTVSLPVNLR | 2014(33); |
| 773 | NASSLFEQWLnGTVSLPVNL | 2015(6); |
| 773 | NNASSLFEQWLnGTVSLPVNL | 2014(33); |
| 773 | EALNNASSLFEQWLnGTVSLPVNLR | 2009(64); 2014(33); |
| 801 | nYTLEQY | 2014(33); |
| 801 | ISWnYTLE | 2014(33); |
| 801 | nYTLEQYQKTSL | 2014(33); |
| 801 | GMQNSGNEISWnY | 2014(33); |
| 801 | YGMQNSGNEISWnYTIEQYQK | 2014(32); |
| 801 | YGMQNSGNEISWnYTLEQYQK | 2007(48); 2012(33); 2014(unpublished);2015(unpublished);2015;2007;2007; |
| 828 | nVTLLSR | 2007(45); 2013(14); 2014(33); 2014(unpublished);2015(unpublished);2015;2015;2007;2007; |
| 828 | ASVKnVTLL | 2014(33); |
| 828 | GLASVKnVTLL | 2014(33); |
| 828 | GLASVKnVTLLSR | 2014(33); |
| 828 | LLYGLASVKnVTLLSR | 2014(33); |
| 828 | EKLLYGLASVKnVTLLSR | 2014(33); |
| 1 | 11 | 21 | 31 | 41 | 51 | 61 | 71 | 81 | 91 |
| MNFAEREGSK | RYCIQTKHVA | ILCAVVVGVG | LIVGLAVGLT | RSCDSSGDGG | PGTAPAPSHL | PSSTASPSGP | PAQDQDICPA | SEDESGQWKN | FRLPDFVNPV |
| 101 | 111 | 121 | 131 | 141 | 151 | 161 | 171 | 181 | 191 |
| HYDLHVKPLL | EEDTYTGTVS | ISINLSAPTR | YLWLHLRETR | ITRLPELKRP | SGDQVQVRRC | FEYKKQEYVV | VEAEEELTPS | SGDGLYLLTM | EFAGWLNGSL |
| 201 | 211 | 221 | 231 | 241 | 251 | 261 | 271 | 281 | 291 |
| VGFYRTTYTE | NGQVKSIVAT | DHEPTDARKS | FPCFDEPNKK | ATYTISITHP | KEYGALSNMP | VAKEESVDDK | WTRTTFEKSV | PMSTYLVCFA | VHQFDSVKRI |
| 301 | 311 | 321 | 331 | 341 | 351 | 361 | 371 | 381 | 391 |
| SNSGKPLTIY | VQPEQKHTAE | YAANITKSVF | DYFEEYFAMN | YSLPKLDKIA | IPDFGTGAME | NWGLITYRET | NLLYDPKESA | SSNQQRVATV | VAHELVHQWF |
| 401 | 411 | 421 | 431 | 441 | 451 | 461 | 471 | 481 | 491 |
| GNIVTMDWWE | DLWLNEGFAS | FFEFLGVNHA | ETDWQMRDQM | LLEDVLPVQE | DDSLMSSHPI | IVTVTTPDEI | TSVFDGISYS | KGSSILRMLE | DWIKPENFQK |
| 501 | 511 | 521 | 531 | 541 | 551 | 561 | 571 | 581 | 591 |
| GCQMYLEKYQ | FKNAKTSDFW | AALEEASRLP | VKEVMDTWTR | QMGYPVLNVN | GVKNITQKRF | LLDPRANPSQ | PPSDLGYTWN | IPVKWTEDNI | TSSVLFNRSE |
| 601 | 611 | 621 | 631 | 641 | 651 | 661 | 671 | 681 | 691 |
| KEGITLNSSN | PSGNAFLKIN | PDHIGFYRVN | YEVATWDSIA | TALSLNHKTF | SSADRASLID | DAFALARAQL | LDYKVALNLT | KYLKREENFL | PWQRVISAVT |
| 701 | 711 | 721 | 731 | 741 | 751 | 761 | 771 | 781 | 791 |
| YIISMFEDDK | ELYPMIEEYF | QGQVKPIADS | LGWNDAGDHV | TKLLRSSVLG | FACKMGDREA | LNNASSLFEQ | WLNGTVSLPV | NLRLLVYRYG | MQNSGNEISW |
| 801 | 811 | 821 | 831 | 841 | 851 | 861 | 871 | 881 | 891 |
| NYTLEQYQKT | SLAQEKEKLL | YGLASVKNVT | LLSRYLDLLK | DTNLIKTQDV | FTVIRYISYN | SYGKNMAWNW | IQLNWDYLVN | RYTLNNRNLG | RIVTIAEPFN |
| 901 | 911 | 921 | 931 | 941 | 951 | ||||
| TELQLWQMES | FFAKYPQAGA | GEKPREQVLE | TVKNNIEWLK | QHRNTIREWF | FNLLESG |
| ID | Publication |
|---|---|
| 6 | Kim DS, Hahn Y: The acquisition of novel N-glycosylation sites in conserved proteins during human evolution. Bmc Bioinformatics 2015, 16. |
| 9 | Smeekens JM, Chen WX, Wu RH: Mass Spectrometric Analysis of the Cell Surface N-Glycoproteome by Combining Metabolic Labeling and Click Chemistry. Journal of the American Society for Mass Spectrometry 2015, 26:604-614. |
| 13 | Yang W, Laeyendecker O, Wendel SK, Zhang B, Sun S, Zhou J-Y, Ao M, Moore RD, Jackson JB, Zhang H: Glycoproteomic Study Reveals Altered Plasma Proteins Associated with HIV Elite Suppressors. Theranostics 2014, 4:1153. |
| 14 | Liu Y, Chen J, Sethi A, Li QK, Chen L, Collins B, Gillet LC, Wollscheid B, Zhang H, Aebersold R: Glycoproteomic analysis of prostate cancer tissues by SWATH mass spectrometry discovers N-acylethanolamine acid amidase and protein tyrosine kinase 7 as signatures for tumor aggressiveness. Molecular & Cellular Proteomics 2014, 13:1753-1768. |
| 15 | Chen R, Seebun D, Ye M, Zou H, Figeys D: Site-specific characterization of cell membrane N-glycosylation with integrated hydrophilic interaction chromatography solid phase extraction and LC-MS/MS. Journal of Proteomics 2014, 103:194-203. |
| 22 | Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941. |
| 32 | Zhang Z, Sun Z, Zhu J, Liu J, Huang G, Ye M, Zou H: High-Throughput Determination of the Site-Specific N-Sialoglycan Occupancy Rates by Differential Oxidation of Glycoproteins Followed with Quantitative Glycoproteomics Analysis. Analytical Chemistry 2014, 86:9830-9837. |
| 33 | Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721. |
| 37 | Boersema PJ, Geiger T, Wisniewski JR, Mann M: Quantification of the N-glycosylated Secretome by Super-SILAC During Breast Cancer Progression and in Human Blood Samples. Molecular & Cellular Proteomics 2013, 12:158-171. |
| 45 | Zhou H, Froehlich JW, Briscoe AC, Lee RS: The GlycoFilter: A Simple and Comprehensive Sample Preparation Platform for Proteomics, N-Glycomics and Glycosylation Site Assignment. Molecular & Cellular Proteomics 2013, 12:2981-2991. |
| 48 | Danzer C, Eckhardt K, Schmidt A, Fankhauser N, Ribrioux S, Wollscheid B, Mueller L, Schiess R, Zuellig R, Lehmann R, et al: Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic beta-Cells and Human Islets. Journal of Proteome Research 2012, 11:1598-1608. |
| 64 | Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, Wang L, Zou H: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res 2009, 8:651-661. |