Detail


Protein	Tight junction protein ZO-1
Gene	TJP1
Status	Reviewed
Source	Liver; OVCAR-3 cell line (Ovarian cancer)
Years	2014-2015

Site	Identified Peptides	Year(Publication ID)
892	nQTYPPYSPQAQPQPIHR	2015(1);
892	SSEPVREDSSGMHHEnQTYPPYSPQAQPQPIHR	2014(33);
1391	nQSNFSSYSSK	2015(1);
1394	NQSnFSSYSSK	2015(1);
1511	nGTEQTQK	2015(1);

Sequence

1	11	21	31	41	51	61	71	81	91
MSARAAAAKS	TAMEETAIWE	QHTVTLHRAP	GFGFGIAISG	GRDNPHFQSG	ETSIVISDVL	KGGPAEGQLQ	ENDRVAMVNG	VSMDNVEHAF	AVQQLRKSGK
101	111	121	131	141	151	161	171	181	191
NAKITIRRKK	KVQIPVSRPD	PEPVSDNEED	SYDEEIHDPR	SGRSGVVNRR	SEKIWPRDRS	ASRERSLSPR	SDRRSVASSQ	PAKPTKVTLV	KSRKNEEYGL
201	211	221	231	241	251	261	271	281	291
RLASHIFVKE	ISQDSLAARD	GNIQEGDVVL	KINGTVTENM	SLTDAKTLIE	RSKGKLKMVV	QRDERATLLN	VPDLSDSIHS	ANASERDDIS	EIQSLASDHS
301	311	321	331	341	351	361	371	381	391
GRSHDRPPRR	SRSRSPDQRS	EPSDHSRHSP	QQPSNGSLRS	RDEERISKPG	AVSTPVKHAD	DHTPKTVEEV	TVERNEKQTP	SLPEPKPVYA	QVGQPDVDLP
401	411	421	431	441	451	461	471	481	491
VSPSDGVLPN	STHEDGILRP	SMKLVKFRKG	DSVGLRLAGG	NDVGIFVAGV	LEDSPAAKEG	LEEGDQILRV	NNVDFTNIIR	EEAVLFLLDL	PKGEEVTILA
501	511	521	531	541	551	561	571	581	591
QKKKDVYRRI	VESDVGDSFY	IRTHFEYEKE	SPYGLSFNKG	EVFRVVDTLY	NGKLGSWLAI	RIGKNHKEVE	RGIIPNKNRA	EQLASVQYTL	PKTAGGDRAD
601	611	621	631	641	651	661	671	681	691
FWRFRGLRSS	KRNLRKSRED	LSAQPVQTKF	PAYERVVLRE	AGFLRPVTIF	GPIADVAREK	LAREEPDIYQ	IAKSEPRDAG	TDQRSSGIIR	LHTIKQIIDQ
701	711	721	731	741	751	761	771	781	791
DKHALLDVTP	NAVDRLNYAQ	WYPIVVFLNP	DSKQGVKTMR	MRLCPESRKS	ARKLYERSHK	LRKNNHHLFT	TTINLNSMND	GWYGALKEAI	QQQQNQLVWV
801	811	821	831	841	851	861	871	881	891
SEGKADGATS	DDLDLHDDRL	SYLSAPGSEY	SMYSTDSRHT	SDYEDTDTEG	GAYTDQELDE	TLNDEVGTPP	ESAITRSSEP	VREDSSGMHH	ENQTYPPYSP
901	911	921	931	941	951	961	971	981	991
QAQPQPIHRI	DSPGFKPASQ	QKAEASSPVP	YLSPETNPAS	STSAVNHNVN	LTNVRLEEPT	PAPSTSYSPQ	ADSLRTPSTE	AAHIMLRDQE	PSLSSHVDPT
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
KVYRKDPYPE	EMMRQNHVLK	QPAVSHPGHR	PDKEPNLTYE	PQLPYVEKQA	SRDLEQPTYR	YESSSYTDQF	SRNYEHRLRY	EDRVPMYEEQ	WSYYDDKQPY
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
PSRPPFDNQH	SQDLDSRQHP	EESSERGYFP	RFEEPAPLSY	DSRPRYEQAP	RASALRHEEQ	PAPGYDTHGR	LRPEAQPHPS	AGPKPAESKQ	YFEQYSRSYE
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
QVPPQGFTSR	AGHFEPLHGA	AAVPPLIPSS	QHKPEALPSN	TKPLPPPPTQ	TEEEEDPAMK	PQSVLTRVKM	FENKRSASLE	TKKDVNDTGS	FKPPEVASKP
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
SGAPIIGPKP	TSQNQFSEHD	KTLYRIPEPQ	KPQLKPPEDI	VRSNHYDPEE	DEEYYRKQLS	YFDRRSFENK	PPAHIAASHL	SEPAKPAHSQ	NQSNFSSYSS
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
KGKPPEADGV	DRSFGEKRYE	PIQATPPPPP	LPSQYAQPSQ	PVTSASLHIH	SKGAHGEGNS	VSLDFQNSLV	SKPDPPPSQN	KPATFRPPNR	EDTAQAAFYP
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
QKSFPDKAPV	NGTEQTQKTV	TPAYNRFTPK	PYTSSARPFE	RKFESPKFNH	NLLPSETAHK	PDLSSKTPTS	PKTLVKSHSL	AQPPEFDSGV	ETFSIHAEKP
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
KYQINNISTV	PKAIPVSPSA	VEEDEDEDGH	TVVATARGIF	NSNGGVLSSI	ETGVSIIIPQ	GAIPEGVEQE	IYFKVCRDNS	ILPPLDKEKG	ETLLSPLVMC
1701	1711	1721	1731	1741
GPHGLKFLKP	VELRLPHCDP	KTWQNKCLPG	DPNYLVGANC	VSVLIDHF

Reference

ID	Publication
1	Sun S, Shah P, Eshghi ST, Yang W, Trikannad N, Yang S, Chen L, Aiyetan P, Hoti N, Zhang Z, et al: Comprehensive analysis of protein glycosylation by solid-phase extraction of N-linked glycans and glycosite-containing peptides. Nat Biotech 2015, advance online publication.
33	Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F, Zou H: Comprehensive Mapping of Protein N-Glycosylation in Human Liver by Combining Hydrophilic Interaction Chromatography and Hydrazide Chemistry. Journal of Proteome Research 2014, 13:1713-1721.

UniProtKB-Q07157

Glycosites

Sequence

Reference