Detail


Protein	Unconventional myosin-VIIa
Gene	MYO7A
Status	Reviewed
Source	Colorectal tumor; Plasma; Serum (HCC)
Years	2013-2015

Site	Identified Peptides	Year(Publication ID)
1237	TFVnGTR	2013(38); 2014(22);
1237	RTFVnGTR	2015(8);

Sequence

1	11	21	31	41	51	61	71	81	91
MVILQQGDHV	WMDLRLGQEF	DVPIGAVVKL	CDSGQVQVVD	DEDNEHWISP	QNATHIKPMH	PTSVHGVEDM	IRLGDLNEAG	ILRNLLIRYR	DHLIYTYTGS
101	111	121	131	141	151	161	171	181	191
ILVAVNPYQL	LSIYSPEHIR	QYTNKKIGEM	PPHIFAIADN	CYFNMKRNSR	DQCCIISGES	GAGKTESTKL	ILQFLAAISG	QHSWIEQQVL	EATPILEAFG
201	211	221	231	241	251	261	271	281	291
NAKTIRNDNS	SRFGKYIDIH	FNKRGAIEGA	KIEQYLLEKS	RVCRQALDER	NYHVFYCMLE	GMSEDQKKKL	GLGQASDYNY	LAMGNCITCE	GRVDSQEYAN
301	311	321	331	341	351	361	371	381	391
IRSAMKVLMF	TDTENWEISK	LLAAILHLGN	LQYEARTFEN	LDACEVLFSP	SLATAASLLE	VNPPDLMSCL	TSRTLITRGE	TVSTPLSREQ	ALDVRDAFVK
401	411	421	431	441	451	461	471	481	491
GIYGRLFVWI	VDKINAAIYK	PPSQDVKNSR	RSIGLLDIFG	FENFAVNSFE	QLCINFANEH	LQQFFVRHVF	KLEQEEYDLE	SIDWLHIEFT	DNQDALDMIA
501	511	521	531	541	551	561	571	581	591
NKPMNIISLI	DEESKFPKGT	DTTMLHKLNS	QHKLNANYIP	PKNNHETQFG	INHFAGIVYY	ETQGFLEKNR	DTLHGDIIQL	VHSSRNKFIK	QIFQADVAMG
601	611	621	631	641	651	661	671	681	691
AETRKRSPTL	SSQFKRSLEL	LMRTLGACQP	FFVRCIKPNE	FKKPMLFDRH	LCVRQLRYSG	MMETIRIRRA	GYPIRYSFVE	FVERYRVLLP	GVKPAYKQGD
701	711	721	731	741	751	761	771	781	791
LRGTCQRMAE	AVLGTHDDWQ	IGKTKIFLKD	HHDMLLEVER	DKAITDRVIL	LQKVIRGFKD	RSNFLKLKNA	ATLIQRHWRG	HNCRKNYGLM	RLGFLRLQAL
801	811	821	831	841	851	861	871	881	891
HRSRKLHQQY	RLARQRIIQF	QARCRAYLVR	KAFRHRLWAV	LTVQAYARGM	IARRLHQRLR	AEYLWRLEAE	KMRLAEEEKL	RKEMSAKKAK	EEAERKHQER
901	911	921	931	941	951	961	971	981	991
LAQLAREDAE	RELKEKEAAR	RKKELLEQME	RARHEPVNHS	DMVDKMFGFL	GTSGGLPGQE	GQAPSGFEDL	ERGRREMVEE	DLDAALPLPD	EDEEDLSEYK
1001	1011	1021	1031	1041	1051	1061	1071	1081	1091
FAKFAATYFQ	GTTTHSYTRR	PLKQPLLYHD	DEGDQLAALA	VWITILRFMG	DLPEPKYHTA	MSDGSEKIPV	MTKIYETLGK	KTYKRELQAL	QGEGEAQLPE
1101	1111	1121	1131	1141	1151	1161	1171	1181	1191
GQKKSSVRHK	LVHLTLKKKS	KLTEEVTKRL	HDGESTVQGN	SMLEDRPTSN	LEKLHFIIGN	GILRPALRDE	IYCQISKQLT	HNPSKSSYAR	GWILVSLCVG
1201	1211	1221	1231	1241	1251	1261	1271	1281	1291
CFAPSEKFVK	YLRNFIHGGP	PGYAPYCEER	LRRTFVNGTR	TQPPSWLELQ	ATKSKKPIML	PVTFMDGTTK	TLLTDSATTA	KELCNALADK	ISLKDRFGFS
1301	1311	1321	1331	1341	1351	1361	1371	1381	1391
LYIALFDKVS	SLGSGSDHVM	DAISQCEQYA	KEQGAQERNA	PWRLFFRKEV	FTPWHSPSED	NVATNLIYQQ	VVRGVKFGEY	RCEKEDDLAE	LASQQYFVDY
1401	1411	1421	1431	1441	1451	1461	1471	1481	1491
GSEMILERLL	NLVPTYIPDR	EITPLKTLEK	WAQLAIAAHK	KGIYAQRRTD	AQKVKEDVVS	YARFKWPLLF	SRFYEAYKFS	GPSLPKNDVI	VAVNWTGVYF
1501	1511	1521	1531	1541	1551	1561	1571	1581	1591
VDEQEQVLLE	LSFPEIMAVS	SSRECRVWLS	LGCSDLGCAA	PHSGWAGLTP	AGPCSPCWSC	RGAKTTAPSF	TLATIKGDEY	TFTSSNAEDI	RDLVVTFLEG
1601	1611	1621	1631	1641	1651	1661	1671	1681	1691
LRKRSKYVVA	LQDNPNPAGE	ESGFLSFAKG	DLIILDHDTG	EQVMNSGWAN	GINERTKQRG	DFPTDSVYVM	PTVTMPPREI	VALVTMTPDQ	RQDVVRLLQL
1701	1711	1721	1731	1741	1751	1761	1771	1781	1791
RTAEPEVRAK	PYTLEEFSYD	YFRPPPKHTL	SRVMVSKARG	KDRLWSHTRE	PLKQALLKKL	LGSEELSQEA	CLAFIAVLKY	MGDYPSKRTR	SVNELTDQIF
1801	1811	1821	1831	1841	1851	1861	1871	1881	1891
EGPLKAEPLK	DEAYVQILKQ	LTDNHIRYSE	ERGWELLWLC	TGLFPPSNIL	LPHVQRFLQS	RKHCPLAIDC	LQRLQKALRN	GSRKYPPHLV	EVEAIQHKTT
1901	1911	1921	1931	1941	1951	1961	1971	1981	1991
QIFHKVYFPD	DTDEAFEVES	STKAKDFCQN	IATRLLLKSS	EGFSLFVKIA	DKVLSVPEND	FFFDFVRHLT	DWIKKARPIK	DGIVPSLTYQ	VFFMKKLWTT
2001	2011	2021	2031	2041	2051	2061	2071	2081	2091
TVPGKDPMAD	SIFHYYQELP	KYLRGYHKCT	REEVLQLGAL	IYRVKFEEDK	SYFPSIPKLL	RELVPQDLIR	QVSPDDWKRS	IVAYFNKHAG	KSKEEAKLAF
2101	2111	2121	2131	2141	2151	2161	2171	2181	2191
LKLIFKWPTF	GSAFFEVKQT	TEPNFPEILL	IAINKYGVSL	IDPKTKDILT	THPFTKISNW	SSGNTYFHIT	IGNLVRGSKL	LCETSLGYKM	DDLLTSYISQ
2201	2211
MLTAMSKQRG	SRSGK

Reference

ID	Publication
8	Ma C, Zhang Q, Qu JY, Zhao XY, Li X, Liu YP, Wang PG: A precise approach in large scale core-fucosylated glycoprotein identification with low- and high-normalized collision energy. Journal of Proteomics 2015, 114:61-70.
22	Nicastri A, Gaspari M, Sacco R, Elia L, Gabriele C, Romano R, Rizzuto A, Cuda G: N-Glycoprotein Analysis Discovers New Up-Regulated Glycoproteins in Colorectal Cancer Tissue. Journal of Proteome Research 2014, 13:4932-4941.
38	Kaji H, Ocho M, Togayachi A, Kuno A, Sogabe M, Ohkura T, Nozaki H, Angata T, Chiba Y, Ozaki H, et al: Glycoproteomic Discovery of Serological Biomarker Candidates for HCV/HBV Infection-Associated Liver Fibrosis and Hepatocellular Carcinoma. Journal of Proteome Research 2013, 12:2630-2640.

UniProtKB-Q13402

Glycosites

Sequence

Reference